The invention provides a low-thermal-conductivity refractory material, a low-thermal-conductivity refractory brick, a preparation method of the low-thermal-conductivity refractory brick and application, and belongs to the technical field of refractory materials. The low-thermal-conductivity refractory material is prepared from the following raw materials: magnesia particles, magnesia fine powder, magnesium aluminate spinel particles, light spinel particles, calcined spinel micro powder and a binding agent. The low-thermal-conductivity refractory brick prepared by taking the low-thermal-conductivity refractory material as a raw material is stable in high-temperature performance, resistant to corrosion of alkali metals, volatile salts and the like, and suitable for a severe environment of a rotary cement kiln or a rotary lime kiln. Meanwhile, the low-heat-conduction refractory brick avoids the problem of Cr<6+> public nuisance pollution of magnesite-chrome bricks, has the characteristics of high strength, low heat conduction, wear resistance, high-temperature load resistance and the like, can meet the requirements of high-temperature strength and mechanical flexibility in use of a cement rotary kiln or a lime rotary kiln, can effectively reduce the dead weight of a rotary kiln and the temperature of a barrel body, reduces te energy and equipment consumption, and improves the service life of the brick for the rotary kiln.