The invention discloses a method for rolling and molding a low-oxygen content aero titanium alloy precision sheet. The low-oxygen content aero titanium alloy precision sheet is obtained by rolling twice by using a twenty high rolling mill. The method comprises the following steps of: rolling by using the twenty high rolling mill, degreasing, recrystallization annealing, cold rolling with the twenty high rolling mill again, degreasing, stress relief annealing, stretcher leveling, longitudinal cutting / transverse cutting, inspecting, packaging, and the like, wherein aero titanium alloy plates, such as TC4, TA15 and the like, with the thickness of 1-5 mm, are used as raw materials. The thickness tolerance of the titanium alloy precision sheet is + / -0.005 mm, the camber is 0.3-1 mm / 1m, the surface quality is No.2B, the surface smoothness is up to 1-2 I-Unit, the grain size is up to 5-6 grades, the surface has no surface contamination layer (such as an oxygen-enriched layer, an alpha layer and the like), the internal stress is distributed uniformly, no anisotropy exists, and the subsequent plastic forming feature is favorable. The invention has the advantages of easy production method, low cost, high product quality and high production efficiency.