40 results about "Pentoxyfylline" patented technology

Complex compounds or adducts of xanthine derivatives, for example propentofylline or pentoxyfylline, or phenazone derivatives, for example phenazone, propylphenazone and aminophenazone, and acesulfame-H, in which the components are present in a molar ratio of 1:1 or 1:2, have a pleasantly sweet taste and are suitable for numerous applications, for example in pharmaceuticals. The compounds can be prepared from the dissolved components by simple reaction.

The invention belongs to the field of medicine, and in particular relates to an anti-scar silicone gel patch and a preparation method thereof. The anti-scar silicone gel patch includes a silicone gel patch and a plastic film; the silicone gel patch includes a silicone gel layer and a textile layer; by weight percentage, the silicone gel layer contains 10-14% Tamoxifen, 6‑10% pentoxifylline, and 75‑85% silicone polymer. Applying tamoxifen and pentoxifylline to silicone gel to make anti-scar silicone gel patch has obvious effect on reducing scar tissue formation. Compared with the lack of any one component, the combined use of the three can play a synergistic effect, can significantly inhibit the proliferation of skin scar cells, and effectively remove scar marks.

The invention relates to the technical field of pharmaceutical preparations, and specifically discloses a pentoxifylline injection and a preparation method thereof. The preparation method is as follows: adding the osmotic pressure regulator in the recipe amount to the water for injection with a total volume of 40-60%, stirring and dissolving, adjusting the pH to 6.5-7.5, then adding the pentoxifylline in the recipe amount, stirring and dissolving, Add water for injection to make up the total amount, adjust the pH to 6.5-7.5, filter through the multi-stage polyethersulfone filter element with decreasing pore size in turn, fill and sterilize to obtain pentoxifylline injection. Compared with the prior art, the present invention achieves the purpose of ensuring product quality stability without adding a stabilizer, and the prescription is simpler. It does not increase, the pH value is stable, the color of the solution is always a colorless and clear solution, and the production cost is also reduced, which is convenient for industrialized production and has high promotion value.

The invention relates to the field of analytical chemistry, in particular to a method for detecting related substances of 6-chloro-2-hexanone. The detection method is determined by gas chromatography, and the chromatographic conditions are as follows: the stationary liquid of the capillary chromatographic column: polyethylene glycol or modified polyethylene glycol; The temperature was raised to 220‑240 °C at a rate of 1 min and maintained for 5‑10 min. The detection method provided by the invention has good sensitivity, accuracy, precision, reproducibility, recovery rate and stability, and the detection result is accurate and reliable. The quality stability of the base and the safety of clinical medication are guaranteed.

The invention provides an artificial propagation technology for schizothorax grahami, and belongs to the technical field of freshwater fish propagation. The artificial propagation technology comprises the steps of parent fish domestication, parent fish selection, spawning induction, artificial insemination, roe incubation and fry breeding, and the spawning induction adopts pentoxifylline, caffeine and calcium dobesilate as spawning induction assistants; meanwhile a compound feed used in the artificial propagation technology is further provided, the compound feed contains resistant starch which is prepared in an acid environment and has a substitution degree of 0.18-0.21. The artificial propagation technology is stable and controllable in process, low in production cost, high in parent fish domestication success rate, small in production damage, high in fertilization rate and hatching rate, low in fry malformation rate and high in drug utilization rate; and the compound feed has the advantages of excellent swelling degree and slow release property, high digestion conversion rate and high biological effective utilization rate, and can improve the gonad maturation and reproductive capacity of parent fish, improve the quality of seminal fluid and egg granules and reduce the embryonic development malformation rate.

The invention discloses a vasoborpyrrole derivative bonded with a blood vessel blocking agent, which is formed by covalently bonding a near-infrared photosensitizer fenpyrrole and a blood vessel blocking agent 2,5-pentoxifylline. Simultaneously, the present invention also discloses a nano-diagnosis reagent obtained by self-assembly of the derivative and the electron-rich amphiphilic polymer methoxy-poly(ethylene glycol)-poly(2-diisopropylamino)methyl methacrylate And its application in type I photodynamic synergistic angioblocking therapy in tumor treatment. The structure of the target product of the present invention is clear, the synthesis process is simple, and the diagnostic and therapeutic reagent based on the target product has both type I photodynamic and pH-responsive vascular blocker release properties. Accurately reach the tumor site, block tumor blood vessels and kill tumor cells, effectively preventing tumor recurrence and metastasis.