89 results about "Aminophenazone" patented technology

This invention describes the coding gene and applications of a nitrobenzene nitro-reducing enzyme, comprising a protein from the following amino acid residue sequences: 1) SEQ ID No. 1 in the sequence table; 2) the amino acid residue sequence in SEQ ID No. 1 is a protein substituted, deleted or added with 1-10 amino acid residues and having the nitrobenzene nitro-reducing enzyme function. The nitrobenzene nitro-reducing enzyme and its coding gene in this invention play an important role in the production of ortho-aminophenols and their derivatives.

The invention relates to a grinding aid as well as a production process and application thereof, and belongs to the technical field of cement additives. The grinding aid is prepared from the followingraw materials, by weight: 3-7 parts of triethanolamine, 1-9 parts of acetic acid, 1-5 parts of butyltriphenylphosphonium bromide, 85-105 parts of water, 2-8 parts of sodium dodecyl benzene sulfonate,3-7 parts of p-aminophenol, 3-9 parts of acid sophorolipid, 7-13 parts of sodium alginate, 1-7 parts of aminophenol, 6-14 parts of biosurfactant and 10-14 parts of hyperdispersant. The mixing amountof the grinding aid in the cement clinker grinding process is 0.03%-0.05%, and the grinding aid has the effect of improving the cement clinker grinding efficiency so as to reduce the energy consumption in the cement clinker grinding process.

The invention, which relates to the technical fields of nano material, catalysis and chemical sensing, provides a novel copper-doped-carbon-nano-dot-based method for enzyme-ratio-free fluorescence detection of the organophosphorus pesticide. With anhydrous copper chloride, tris(hydroxymethyl) aminomethane and L-dopa as raw materials, fluorescent copper-doped carbon nano-dots with high stability and peroxidase activity are synthesized by a one-step hydrothermal method. O-phenylenediamine oxidized by hydrogen peroxide is catalyzed based on peroxidase-like activity of the copper-doped carbon nano-dots and fluorescent oxidized molecule 2,3-diaminophenazine is genreated, so that two fluorescent emission peaks of the copper-doped carbon nano-dot and 2,3-diaminophenazine are generated at the lengthes of 375 nm and 555 nm; and the ratio of the fluorescence intensities at the two wavelengths is linearly related to the concentration of the organophosphorus pesticide, thereby realizing enzyme-ratio-free fluorescence detection of the organophosphorus pesticide. The sensor is constructed simply and easily; no biological enzyme is needed; the influences of the probe concentration and environmental factor are low; and the linear range is wide and the sensitivity is high.

The invention relates to the technical field of chemical isomer analysis and measurement, in particular to a functionalized mesoporous material modified electrode and a method for measuring three aminophenol isomers at the same time thereby. The method comprises the preparation of the functionalized mesoporous material modified electrode and the operation for measuring three aminophenol isomers at the same time by using the electrode. The functionalized mesoporous material modified electrode material is simple and convenient to synthesize and low in price, and the electrode is simple and convenient to prepare and easy to update and has the advantages of good repeatability, no toxicity and no pollution to the environment; and meanwhile, the measuring method effectively reduces the interference of concomitant substances and has the advantages of good selectivity and high sensitivity.

The invention discloses a rosa roxburghii tratt beverage and a preparation method thereof, wherein the rosa roxburghii tratt beverage comprises a rosa roxburghii tratt juice, sulfur dioxide, citric acid, white granulated sugar, and water. The preparation method comprises: selecting fresh rosa roxburghii tratt fruit with a maturity of 80-90%, washing, placing into a breaker, breaking, pressurizing, and collecting a fruit juice; sealing the fruit juice into a pool, and standing for 7 days; adding gelatin and treating; filtering to obtain a rosa roxburghii tratt juice; and mixing the rosa roxburghii tratt juice, sulfur dioxide, citric acid, white granulated sugar and water according to a certain ratio, uniformly stirring, disinfecting, and packaging to obtain the rosa roxburghii tratt beverage. According to the present invention, the product has characteristics of clear and transparent color, sweet and sour taste and rich nutrition, and contains a large amount of carbohydrates, vitamins and trace elements necessary for the human body; the method has advantages of simple process and convenient large-scale production; and the experiment results show that the rosa roxburghii tratt provides protection effects for aminophenazone and nitrite-induced liver poisoning and liver cancers, provides prevention and treatment effects for lead poisoning, can be adopted as the auxiliary agent for prevention and treatment of lead poisoning, and has characteristics of good lead expelling better and no toxic-side effect.

The invention relates to a preparation method of fluorine-containing autocatalytic phthalonitrile resin. The method comprises the following steps: (1) adding fluorine-containing aminophenol, a basic catalyst, an organic solvent and 4-nitrophthalonitrile into a reactor, and reacting to obtain a fluorine-containing autocatalytic phthalonitrile monomer; and (2) putting the fluorine-containing self-catalyzed cyanophenyl monomer into an aluminum foil mold, and carrying out gradient temperature rise and curing to obtain the fluorine-containing phthalonitrile resin material. The synthesis period is short, the yield is high, the processing technology is simple, and the obtained resin can be widely applied to the fields of composite materials, aerospace, electronic packaging and the like.

The invention discloses a method for detecting acetaminophen and other chemicals in a herbal beverage. The method comprises the following steps: 1) preparing a herbal beverage sample solution; 2) preparing a series of control sample solutions; 3) making a standard curve; and 4) determining the herbal beverage sample solution. The detection method has the advantages of simplicity in operation, fastdetection speed, good precision and high sensitivity, meets high-throughput screening requirements, and fills in the gap in the detection of acetaminophen and other chemicals in the herbal beverage at present.

The invention discloses a method for detecting compound aminophenazone and barbital injection by means of high performance liquid chromatography. By virtue of the method, all effective components in the compound aminophenazone and barbital injection can be completely separated from impurity peaks, the content of each component in the injection can be determined correctly, the operation is simple and convenient without special flowing phase or chromatographic column, the equipment loss is small, the cost is low and a guarantee is provided for the injection drug safety.

The invention relates to the preparation and application of a nano-nickel/silver/copper (Ni/Ag/Cu) composite catalyst and belongs to the field of nano-catalyst preparation and catalytic research. The preparation comprises the following steps: preparing a hollow Ni/Ag/Cu composite nano-catalyst by using copper nitrate, silver nitrate and nickel nitrate as raw materials; performing reaction through the catalyst by using p-nitrophenol and absolute ethyl alcohol as the raw materials to raise the reaction temperature to 80-160 DEG C, maintaining the temperature, and reacting for 2-8h to obtain high-purity p-aminophenol. The hollow Ni/Ag/Cu composite nano-catalyst is in a spherical particle shape, is small in dosage and is high in catalytic activity and stability. A method for preparing the p-aminophenol through the nano-Ni/Ag/Cu composite catalyst is simple in process requirement and meets an industrialization requirement.

The invention belongs to the technical field of binders, and particularly relates to an environment-friendly anti-oxidation carton adhesive and a preparation method thereof. The adhesive comprises the following components: dry starch, p-aminophenol epoxy resin, hydrogen peroxide, borax, sodium dicyandiamide, dimethyl carbonate, phthalic anhydride polyester polyol, polyethylene terephthalate, triethanolamine and antioxidant. The anti-oxidant is a compound of hindered phenol, phosphite ester, and a metal ion chelating agent. The adhesive not only has high bonding strength, but also has the effects of non-discoloring, mildewing and the like when used for a long time.

The invention discloses an orange fluorescent carbon dot and application thereof in detection of peroxynitrite ions. The carbon dot (CDs) is prepared from rhodamine B and p-aminophenol as raw materials through a one-step hydrothermal synthesis method; the carbon dot is a zero-dimensional carbon nanomaterial and can emit bright orange fluorescence. The preparation method is simple and convenient, and the prepared carbon dots are good in water solubility and stable in fluorescence property. The peroxynitrite ions can be rapidly and sensitively detected by taking the carbon dots as a fluorescentprobe. When peroxynitrite ions exist, fluorescence of the carbon dots is effectively quenched by peroxynitrite. Meanwhile, the color of the CDs solution is changed into blue black from pink. Comparedwith a pure fluorescence analysis method, the analysis method for detecting the ONOO<-> has the advantages that a dual-mode output method has more advantages in practical application, and it is indicated that the analysis method has potential application prospects in discussion of the effect of the ONOO <-> in cytobiology.

The invention relates to the technical field of the analysis and determination of a geometric isomer, in particular to a method for preparing a hexadecyl functionalized mesoporous silicone modified glass carbon electrode by utilizing a constant-current deposition method and also for simultaneously determining three geometric isomers of aminophenol. The electrode is simple to produce, the price of raw materials is low, the stability is good, no toxicity exits, and the environment is not polluted; moreover, by adopting the determination method, the interference of coexisting substances can be effectively reduced, the selectivity is good, and the sensitivity is high.

The invention discloses a method for preparing p-aminophenol from nitrobenzene, which mainly comprises the following steps: carrying out hydrogen reduction reaction in a CO2/H2O system in a high-pressure reaction kettle at 100-150 DEG C for 4-7 hours by using Pt as a main active component and Mg, Cr and Ni as assistants under the conditions that the H2 pressure is 0.5-2 MPa and the CO2 pressure is 4-6 MPa; after the reaction is finished, filtering the catalyst out and drying the same for continuous use, wherein the selectivity of the p-aminophenol can reach 85% or above. According to the reaction, a CO2/H2O system is used for replacing a traditional sulfuric acid system, the problems of sulfuric acid pollution to the environment and aftertreatment are solved, meanwhile, the problem of corrosion of sulfuric acid to equipment is avoided, the catalyst with the HZSM-5 molecular sieve as the carrier can adjust the acidity of the carrier, meanwhile, the defect that the acidity of the CO2/H2O system is insufficient is overcome, and the stability of the catalyst is good.

The invention relates to an asymmetric squarylium cyanine colorimetric probe for identifying copper ions and application of the asymmetric squarylium cyanine colorimetric probe, and a preparation method of the asymmetric squarylium cyanine colorimetric probe comprises the following steps: synthesizing 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole from 1, 1, 2-trimethyl-1H-benzo [e] indole and iodoethane, synthesizing diethoxy squaric acid from squaric acid and ethanol, and synthesizing diethoxy squaric acid from 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole and 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole. The preparation method comprises the following steps: synthesizing 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole squaric acid hemicyanine from 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole, and synthesizing asymmetric double-square acid cyanine from the 3-ethyl-1, 1, 2-trimethyl-1H-benzo [e] indole squaric acid hemicyanine and 3-diethylaminophenol for selective recognition and detection of copper ions. The asymmetric squarylium cyanine chemical sensor has the beneficial effects that the asymmetric squarylium cyanine chemical sensor has the characteristics of good optical performance and high sensitivity. When the copper ions are detected and identified, the color of the solution is obviously changed, so that colorimetric detection is facilitated.

The invention discloses a detection method for relative substances in a compound aminophenazone and barbital injection. The method utilizes a high performance liquid chromatography to determine. The detection method disclosed by the invention can be used for completely separating the peaks of effective components and impurities of the compound aminophenazone and barbital injection at the same time. The invention provides an effective relative substance detection method. Meanwhile, the method can be used for effectively detecting impurities generated in products which are stored for long time or are degraded, has a wide applicable range and provides guarantees to medicine safety of the injection.

The invention discloses an indole ring substituted aminophenoxy zinc complex, a preparation method thereof and application of the indole ring substituted aminophenoxy zinc complex in catalyzing lactone ring-opening polymerization. The preparation method comprises the steps of directly reacting a neutral ligand with a metal raw material compound in an organic medium, filtering, concentrating, and recrystallizing to obtain the target compound. The indole ring substituted aminophenoxy zinc complex disclosed by the invention is an efficient lactone ring opening polymerization catalyst and can be used for catalyzing polymerization reaction of lactide and other lactones; and the method has a good effect on ring-opening polymerization of racemic lactide. The indole ring substituted aminophenoxy zinc complex has very obvious advantages that the raw materials are easy to obtain, the synthesis route is simple, the product yield is high, the catalytic activity and the three-dimensional adjustability are better, a high-impurity-specification and high-molecular-weight polyester material can be obtained under general conditions, and isotactic selectivity can be achieved by adding small organic molecules with an auxiliary coordination effect. The structural formula is shown in the description.

The invention relates to a paracetamol, aminophenazone, caffeine and chlorphenamine maleate tablet and a preparation method thereof. The tablet is prepared from the following effective active ingredients: paracetamol, aminophenazone, caffeine and chlorphenamine maleate and also comprises common auxiliaries such as filler, lubricant, a disintegrating agent and an adhesive. According to the preparation method, the defects of sticking pinch, greasy pinch and the like caused by adhesive objects in the tabletting process by screening auxiliaries in the formula, and the prepared tablet is smooth and clean in appearance.

The invention discloses a tissue adhesive as well as a preparation method and application thereof. According to the tissue adhesive, when the tissue adhesive adheres to the surface of pigskin for lessthan 8h, the adhesion strength is smaller than or equal to 55kPa, and when the surface adhesion time is more than or equal to 8h, the adhesion strength I greater than 55kPa. Due to the fact that thetissue adhesive contains amino, phenolic hydroxyl and a natural cross-linking agent, the tissue adhesive can form non-covalent and covalent bonds with groups such as the amino and the sulfydryl on thesurface of tissue, and the tissue adhesive has high adhesion strength through the synergistic effect of multiple action bonds. The preparation method of the tissue adhesive is simple in process and low in raw material cost, and the tissue adhesive is a natural source material. The tissue adhesive has good biocompatibility, is high in adhesive strength under physiological conditions, is simple, convenient and safe to use, and has a good application prospect in tissue adhesion repair.

The invention discloses a benzothiazole ring substituted aminophenoxy zinc complex, a preparation method thereof, and an application of the benzothiazole ring substituted aminophenoxy zinc complex inhigh-activity and high-selectivity catalysis of lactone ring opening polymerization. The preparation method comprises the following steps: directly reacting a neutral ligand with a metal raw materialcompound in an organic medium, filtering, concentrating, and recrystallizing to obtain the target compound. The benzothiazole ring substituted aminophenoxy zinc complex disclosed by the invention is an efficient lactone ring opening polymerization catalyst and can be used for catalyzing a polymerization reaction of lactide and other lactones; and especially for racemic lactide, polylactide with high isotacticity can be obtained. The benzothiazole ring substituted aminophenoxy zinc complex has the very obvious following advantages: the raw materials are easy to obtain, the synthesis route is simple, the product yield is high, the catalytic activity and stereoselectivity are very high, a high-regularity and high-molecular-weight polyester material can be obtained, and the requirements of industrial departments can be met. The structural formula is shown in the specification.

The invention discloses a 5-aryl-7-methoxycarbonyl dibenzo [b, e][1, 4] oxazepine-11(5H)-ketone compound and a preparation method thereof. The preparation method comprises the steps of carrying out condensation, isomerization and dehydration reaction on 3-dehydrogenated methyl shikimate and an aryl amine compound in the presence of an organic solvent and a catalyst in the microwave condition to obtain an aryl-substituted o-aminophenol intermediate; further adding o-halogen benzoic acid and an alkali neutralization catalyst in the microwave condition, cooling, pumping filtering, and carrying out recrystallization to obtain an N, N-diaryl-substituted o-aminophenol intermediate; and in the organic solvent, carrying out molecular lactonization cyclization reaction on the N, N-diaryl-substituted o-aminophenol intermediate in the presence of the catalyst and alkali to obtain the 5-aryl-7-methoxycarbonyl dibenzo [b, e][1, 4] oxazepine-11(5H)-ketone compound. The preparation method is simple, is short in the reaction time, is convenient for postprocessing and is high in the yield.

The invention provides a nickel-containing wastewater filtration system in the production process of aminophenazone. The filtration system includes a washing tower, a first-level sedimentation tank, afiltration liquid storage tank, an infusion pump and a PM filter. Washing water which contains an activated Ni catalyst is introduced from the washing tower into the first-level sedimentation tank, the obtained water overflows through an overflow pipeline of the first-level sedimentation tank into the filtration liquid storage tank after sedimentation is performed, and the obtained clear liquid is discharged outside after filtration is performed, so that nickel-containing wastewater is filtered automatically, the cleaning frequency is increased, regularization of cleaning is achieved, and itis ensured that residues at the bottom layer of the sedimentation tank can be discharged more easily than before; and secondary sedimentation tanks are not used any more, so that the labor operation of employees is reduced.

The invention discloses a preparation method of an amino phenolic resin-based pyrrole nitrogen-doped carbon electrode material. The preparation method comprises the following specific steps of: A, preparing 3-aminophenol-3-halogenated phenol-formaldehyde resin, B, carrying out low-temperature carbonization on the 3-aminophenol-3-halogenated phenol-formaldehyde resin, and C, performing low-temperature activation on the carbonized 3-aminophenol-3-halogenated phenol-formaldehyde resin. The doping of a single pyrrole nitrogen configuration in the carbon material is realized through low-temperatureheat treatment; the utilization efficiency of the nitrogen-doped active sites in pseudocapacitance reaction is improved; and meanwhile, the energy consumption during preparation of the nitrogen-dopedcarbon material is reduced, and when the nitrogen-doped carbon material is used as a supercapacitor electrode material, the amino phenolic resin-based pyrrole nitrogen-doped carbon electrode materialshows the characteristics of high capacity, typical pseudocapacitance, good rate capability and high cycling stability.

The invention relates to a preparation method of a paracetamol, aminophenazone, caffeine and chlorphenamine maleate tablet, and belongs to the technical field of pharmaceutical chemical engineering. The preparation method has a simple technology, can evenly mix paracetamol, aminophenazone, and various raw materials, and is capable of avoiding the phenomenon of mutual dissolution between paracetamol and aminophenazone. The preparation method comprises the following steps: weighing paracetamol, aminophenazone, caffeine and chlorphenamine maleate according to a certain ratio, adding the components into a mixing machine, adding microcrystalline cellulose, dextrin, and hydroxypropyl cellulose, evenly mixing; pressing the evenly-mixed materials into tablets in a dry pressing machine, then grinding the tablets into particles, adding pre-gelatinized starch, magnesium stearate, and sodium carboxyl methyl starch, evenly mixing, and pressing the mixture into tablets for a second time.

This invention describes a hydroxylamine benzene dismutase, its coding gene and applications. The hydroxylamine benzene dismutase in this invention comprises a protein from the following amino acid residue sequences: 1) SEQ ID No. 1 in the sequence table; 2) the amino acid residue sequence in SEQ ID No. 1 is a protein substituted, deleted or added with 1-10 amino acid residues and having the nitrobenzene nitro-reducing enzyme function. The hydroxylamine benzene dismutase and its coding gene in this invention play an important role in the production of ortho-aminophenols and their derivatives.