29 results about "Aminophenazone" patented technology

The present invention discloses a class of nitrogen heterocycle-substituted hexa-dentate aminophenoxy rare earth complexes (I), a preparation method thereof, and an application thereof in the highly active catalytic ring-opening polymerization of lactones. The preparation method comprises the following steps: reacting a neutral ligand with a metal raw material compound in an organic medium, then adding an alcohol for reaction, and obtaining the target compound through filtration, concentration, and recrystallization. The nitrogen heterocycle-substituted hexa-dentate aminophenoxy rare earth complex of the present invention is a highly efficient catalyst for the ring-opening polymerization of lactones, and can be used for catalyzing the polymerization reaction of lactones such as lactide, and catalyzing the one-pot copolymerization of lactide and ε-caprolactone to obtain a multi-block copolymer. The nitrogen heterocycle-substituted hexa-dentate aminophenoxy rare earth complex of the present invention has good tolerance to impurities, has very high catalytic activity, and can obtain high molecular weight polyester materials. A has a structure shown in formula (II), (III), (IV) or (V); B has a structure shown in formula (VI) or (VII).

The invention relates to the technical field of enzyme-linked immunosorbent assay, and discloses a quality control serum diluent as well as a preparation method and application thereof, and the quality control serum diluent is prepared from the following raw materials: boric acid, borax, sodium caseinate, liquid gelatin, aminopyrine, an osmotic pressure stabilizer and bovine serum. The quality control serum diluent prepared by adopting the formula has no potential interfering substances (such as formaldehyde and thiomersalate), has excellent thermal stability and long-term stability, is applied to quality control serum dilution, is beneficial to improving the detection accuracy, ensures that the characteristics of the diluent meet the requirements when the diluent is used every time, and provides stable reference data for the detection process.

The invention relates to a preparation method and application of a CoNi alloy nanoparticle doped double-shell hollow carbon material, and belongs to the field of nano material preparation technology and electromagnetic wave absorption application. 3-aminophenol and formaldehyde are subjected to a condensation polymerization reaction to synthesize phenolic resin balls, the phenolic resin balls are placed in 3-aminophenol and formaldehyde again to react, and the double-shell hollow phenolic structure is obtained. And adding the double-shell hollow phenolic aldehyde structure into cobalt nitrate hexahydrate (Co (NO3) 2.6 H2O) and 2-methylimidazole for low-temperature reaction, then adding a solution of (Ni (NO3) 2.6 H2O) for reaction at high temperature and high pressure, and drying to obtain the CoNi alloy nanoparticle doped double-shell hollow carbon material. According to the preparation method disclosed by the invention, the double-shell structure is taken as a main template, and the CoNi alloy nanoparticles are used as active components to be doped in the double-shell hollow structure in situ, so that the cascade synthesis of the microstructure of the nano material is greatly enriched, and the obtained CoNi alloy nanoparticle doped double-shell hollow carbon material has excellent electromagnetic wave absorption performance.

Compositions and methods for inhibiting and retarding polymerization of monomeric compositions are described that use a naphthoquinone and an oxygenated aminophenol. When present in a monomer-containing composition, the combination of naphthoquinone and oxygen-containing aminophenol provides an unexpectedly beneficial anti-polymerization agent effect, thereby inhibiting the formation of unwanted fouling polymers. The anti-polymerization agent combination can be added to a hydrocarbon composition, such as petroleum, that can include a polymerizable component, such as styrene, wherein the hydrocarbon composition is purified or processed, such as under distillation.

The invention discloses a synthesis method of p-aminophenol derivatives, which comprises the following steps: dissolving a compound A in a mixed solvent of acetonitrile and water, cooling to 0-5 DEG C, then adding an organic and inorganic acid catalyst, reacting at room temperature, distilling to remove the solvent, and then adding citric acid to continuously react to obtain a compound B; the initial raw materials are simple and easy to obtain and easy to purchase and store on a large scale, and the synthesized p-aminophenol compound is high in purity and can meet the requirements of most industrial applications on product purity.

The invention discloses a colorimetric detection method for cMyBP-C protein based on nano-enzyme activity, preparation of a bismuth selenide / nano-gold composite material and application of the bismuth selenide / nano-gold composite material in protein detection. The method comprises the following steps: performing ultrasonic stripping on a bismuth selenide block to obtain a few-layer bismuth selenide dispersion liquid; and then sequentially adding a sodium borohydride aqueous solution and a chloroauric acid aqueous solution under a stirring condition, and carrying out in-situ reduction to form gold nanoparticles loaded on the surface of bismuth selenide. The composite material has the capability of catalyzing reduction of p-nitrophenol into p-aminophenol, and the color of the solution is changed from yellow to colorless. After the cMyBP-C antibody is modified on the surface of the composite material, the catalytic activity is inhibited; after a to-be-detected sample is added, the antibody and the protein are specifically combined to cause dissociation, and the catalytic activity is recovered. The cMyBP-C protein is quantitatively detected by observing the color change of the solution or monitoring the reduction of the ultraviolet absorbance at 400 nm.

The present application relates to a hybridoma cell strain secreting a chlorinated nitrogen aminophenazone monoclonal antibody and its application, and belongs to the technical field of immune detection. The hybridoma cell strain secreting a chlorinated nitrogen aminophenazone monoclonal antibody was preserved in the China General Microbiological Culture Collection Center on April 24, 2026, and the address of the preservation is No. 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No. 46821. The monoclonal antibody secreted by the hybridoma cell strain of the present application has good detection sensitivity (IC 50 Value is 0.27 ng / mL) to chlorinated nitrogen aminophenazone, and can be used for the residual detection of chlorinated nitrogen aminophenazone.

The invention discloses a chlorine-free etching agent for a photovoltaic printing tungsten steel mesh and a preparation method and application of the chlorine-free etching agent for the photovoltaic printing tungsten steel mesh, and the chlorine-free etching agent for the photovoltaic printing tungsten steel mesh comprises the following components in percentage by weight: 0-2.5% of o-aminophenol sulfonic acid; 0 to 3% of diphenyl sulfonyl-4, 4 '-difluoro-3, 3'-disodium disulfonate; 0 to 1.2 percent of 2, 5-bis (methylsulfonyl)-1, 4-phenylenediamine; 0.5 to 2% of 2, 5-dimethyl phenyl thiourea; 0.2 to 3% of 5-(difluoromethoxy)-2-sulfydryl-1H-benzimidazole, and the balance of water; 0 to 2% of a hydroxyl-terminated vinyl pyrrolidone-styrene copolymer; 33-70% of an acidic etching main agent; the acidic etching main agent is a mixture of nitric acid, hydrofluoric acid and phosphoric acid. According to the etching solution, through the synergistic effect of all the components, the effect that the diameter of the tungsten steel mesh is accurately etched from 10 micrometers to 6 micrometers at the normal temperature is achieved, and the smoothness and brightness of the surface of the etched tungsten steel mesh are considered.

This invention discloses a ZnCdS / APF composite photocatalyst, its preparation method, and its application, belonging to the field of photocatalysis technology. The composite photocatalyst uses a ZnCdS solid solution as the light-absorbing core and aminophenol-formaldehyde resin (APF) as the interface modification layer. The two are polymerized in situ to form a tight heterojunction. This invention uses zinc acetate, cadmium acetate, and thioacetamide as precursors to synthesize ZnCdS via ethylenediamine-assisted hydrothermal synthesis; then, using 3-aminophenol and formaldehyde as monomers, APF is grown in situ on the ZnCdS surface under ammonia catalysis, followed by washing and drying to obtain the final product. This preparation process is mild, requires no precious metals, and is easily scalable. The composite photocatalyst achieves a photocatalytic hydrogen peroxide production rate of up to 5318 μmol g under visible light irradiation and an oxygen atmosphere. ‑1 h ‑1 Compared to pure ZnCdS (2983 μmol g), ‑1 h ‑1 The photocatalyst exhibits a 78.3% improvement in light absorption capacity, carrier separation efficiency, and photoelectrochemical performance, all significantly superior to the pure-phase material. Characterization results, including SEM, UV-vis DRS, Mott-Schottky, EIS, and transient photocurrent response, confirm the synergistic enhancement effect of APF on ZnCdS. This composite photocatalyst shows broad application prospects in the green synthesis of H2O2.

The invention belongs to the technical field of organic synthesis, and particularly relates to an alkyl aminophenol compound and a synthesis method thereof. Aiming at the problems of harsh conditions, insufficient selectivity and the like of the existing arylamine C-N bond breaking method, the invention provides a novel method for synthesizing the p-alkyl aminophenol compound by oxidizing aromatic amine through PhI (OAc) 2 to selectively break a C (aryl)-N bond under a mild condition. According to the method, a series of p-alkyl aminophenol compounds with potential biological activity can be synthesized within 3 hours at the yield of 56-82%, and the method is suitable for preparation of derivatives such as indole ethylaminophenol and adamantane methylaminophenol.

The invention belongs to the technical field of drug research, and particularly relates to a polyvinyl alcohol modified carbon dot and application. The polyvinyl alcohol modified carbon dots are prepared according to the following steps: taking p-aminophenol and ethidene diamine as precursors, and carrying out hydrothermal reaction to obtain p-aminophenol-ethidene diamine carbon dots; and performing surface modification on the p-aminophenol-ethylenediamine carbon dots by using polyethylene glycol to obtain the p-aminophenol-ethylenediamine carbon dots. The polyvinyl alcohol modified carbon dots have good anti-oxidation and anti-inflammatory effects, and can be used for preparing drugs for treating renal ischemia reperfusion injury.

The invention discloses a method for detecting polyvinyl chloride micro-plastic through photoelectrochemistry. Specifically, the invention develops a polyvinyl chloride micro-plastic photoelectrochemical aptamer sensor, and establishes a detection method based on the sensor, the method comprises the following steps: forming a double-chain compound by a thrombin aptamer P1 and a polyvinyl chloride aptamer P2, releasing P1 after the P2 recognizes PVC, splitting P1 under the action of exonuclease I, and detecting the PVC by virtue of the split P1. At the moment, free thrombin in the system degrades the p-aminophenol modified polypeptide to generate AP, a Bi < 3 + > / Bi < 2 + > MMCT process is triggered, enhanced photocurrent is output, AP regeneration is promoted through DI-mediated EDRR, the photocurrent is further amplified, and the sensitivity of a photoelectrochemical (PEC) sensor for detecting PVC is remarkably improved. The detection method is easy to operate, high in response speed, good in selectivity and high in sensitivity, and has good accuracy in detection of actual samples (such as cosmetics as lipsticks and liquid foundation).

The invention discloses a copper ion detection fluorescent probe LCY as well as a preparation method and application thereof, the copper ion detection fluorescent probe LCY takes benzothiazole-2-acetonitrile as a fluorophore, and the structure of the copper ion detection fluorescent probe LCY is shown in the specification. The fluorescent probe LCY with the m-aminophenol derivative as a parent is prepared through condensation of the m-aminophenol derivative and benzothiazole-2-acetonitrile, and the probe is novel in structure, has specific selection on copper ions, is short in response time and high in sensitivity, has selectivity on glyphosate, can effectively detect glyphosate residues and has good application prospects. More importantly, the preparation method of the probe is simple, and the obtained product is solid powder, easy to store and good in stability. # imgabs0 #

The invention discloses a phenolic amine adduct in the technical field of epoxy curing agent preparation and a preparation method thereof. The method comprises the following steps: 1) mixing an aminophenol compound, a solvent, and a chain extender at 80-120° C. for reaction for 4-8 hours, and then adding a capping agent and mixing to obtain an intermediate; and 2) dropwise adding the intermediate to a raw amine, and reacting at 60-90° C. for 2-8 hours to obtain the phenolic amine adduct. The method aims to obtain an amine curing agent having a phenolic hydroxyl group in its structure. Compared with the phenalkamine technology based on the Mannich reaction, the method does not require the use of toxic aldehydes and ketones, nor does it require a complex dehydration process. The synthesis process is simple and efficient, and the raw material conversion rate is high. The product has the advantages of fast curing speed, low-temperature curing capability, and no oil surface whitening in a high-humidity environment as an epoxy resin curing agent. By selecting specific raw materials, a water-based product can also be prepared, and has a wide range of uses.

The invention relates to a p-aminophenol electrochemical sensor, a preparation method and application. The invention discloses a one-week WSe2 and Se / Ti < 3 > C < 2 > T < x > MXenes nano material compound modified glassy carbon electrode and a preparation method thereof. The glassy carbon electrode sensor has the advantages of convenience in operation, low cost, high detection speed and real-time monitoring. The p-aminophenol can be accurately detected, the linear range of detection is wide, the detection limit is low, and the anti-interference performance is high.

The invention discloses a preparation method of a low-viscosity aminophenol polyglycidyl derivative, which comprises the following steps: (1) under the condition that the reaction temperature is not higher than 25 DEG C and in the presence of a catalyst, enabling aminophenol and epoxy chloropropane to be subjected to full ring-opening reaction by utilizing a water-soluble polar cosolvent; (2) adding water accounting for 0.5-10% of the mass of the epichlorohydrin at the temperature not higher than 60 DEG C, adding alkali metal hydroxide in batches, and carrying out dehydrochlorination reaction; (3) dissolving the crude product obtained in the step (2) in a water-insoluble solvent, and washing with a low-concentration alkali metal hydroxide aqueous solution at 30-100 DEG C; and (4) washing with a low-concentration sodium dihydrogen phosphate solution, and carrying out reduced pressure distillation on a solvent layer to remove the solvent, thereby obtaining the aminophenol polyglycidyl derivative. Through the mode, the aminophenol polyglycidyl derivative with close to three functionality degrees can be synthesized.

The present disclosure provides indane bis-o-aminophenol compounds capable of producing soluble polyimides, functional polyimides, and poly-o-hydroxyamides.

The invention discloses an organic gas adsorption gel for a dust-free workshop. The preparation method comprises the following steps: weighing the following preparation raw materials in parts by mass: 60-80 parts of bis (3-aminophenyl) polydimethylsiloxane; 10 to 30 parts of an acid ester compound; 1 to 10 parts of 2, 2 '-azo-2-methyl propionitrile; 1-5 parts of styrene and derivatives thereof; 0.1 to 0.5 part of divinyl benzene; 1 to 50 parts of ultrapure water; a three-dimensional cross-linked flexible network is formed through in-situ free radical polymerization; the structure has the non-polar adsorption capacity of a polysiloxane main chain and the specific effect of an amino / phenolic hydroxyl functional group on polar VOCs, various organic gases such as benzene, methylbenzene and formaldehyde can be efficiently captured, and byproducts are not released; the preparation process comprises the steps of ultrasonic dispersion, vacuum defoaming, gradient heating polymerization and solvent replacement, the specific surface area of the obtained gel is 280-420 m / g, the pore diameter is 3.5-8.2 nm, the gel can be directly coated and used in an ISO Class 1-5 level dust-free workshop, and the gel has the characteristics of high adsorption broad spectrum, structural stability, greenness and recyclability.

The present invention provides a polymerization method of 1,3-dioxolan-4-one compounds, comprising the following steps: carrying out a polymerization reaction on the 1,3-dioxolan-4-one compounds under the catalysis of an imidazole-substituted aminophenoxy zinc complex catalyst. The imidazole-substituted aminophenoxy zinc complex catalyst has the structure shown in formula (I), and its preparation method comprises the following steps: directly reacting a neutral ligand with a metal raw material compound in an organic medium, and then obtaining the target compound through filtration, concentration, and recrystallization steps. The 1,3-dioxolan-4-one compounds have the structure shown in formula (II). Compared with the prior art, the polymerization method provided by the present invention enables the 1,3-dioxolan-4-one compounds to efficiently achieve homopolymerization and random copolymerization with lactide.

The application discloses a kind of dimethylene pyridine bridged double aminophenol alkali metal complex and its preparation method and application in high activity catalytic lactone ring-opening polymerization.The preparation method includes the following steps: dimethylene pyridine bridged double aminophenol ligand is reacted with metal hydride in organic medium, then is filtered, concentrated, and the target dimethylene pyridine bridged double aminophenol alkali metal complex is obtained by recrystallization step.The dimethylene pyridine bridged double aminophenol alkali metal complex of the application is a kind of high-efficiency lactone ring-opening polymerization catalyst, and can be used for the polymerization reaction of high activity catalytic lactide etc.The dimethylene pyridine bridged double aminophenol alkali metal complex of the application has very obvious advantages: raw material is easy to obtain, synthesis route is simple, has high catalytic activity, can obtain high molecular weight polyester material, meets the needs of industrial department.The structural formula is as shown below:

The invention belongs to the technical field of environmental adsorption materials, and particularly relates to a preparation method and application of a mineral nanofiber and graphene compounded three-dimensional aerogel material. The three-dimensional aerogel material takes sepiolite, graphene oxide and sodium alginate as raw materials, and the preparation method comprises the following steps: performing amino functionalization on the sepiolite, performing condensation reaction on the sepiolite and a graphene oxide single-layer suspension to obtain a compound, and then adding sodium alginate for coating to form aerogel. According to the method, sepiolite is uniformly dispersed between graphene oxide sheet layers, the defects that sepiolite fibers are prone to agglomeration and entanglement and graphene oxide is prone to stacking and aggregation are overcome, adsorption active sites on the surfaces of sepiolite and graphene oxide can be fully exposed, meanwhile, sodium alginate is introduced to prepare the aerogel, and the adsorption activity of the sepiolite and graphene oxide is improved. The problem that a traditional adsorption material is difficult to recycle is solved. The three-dimensional aerogel material prepared by the method has the characteristics of rich surface active sites, looseness, porosity, easiness in recovery and the like, has excellent adsorption performance on triamterene and tetracycline, and has wide application prospects in the field of removal of novel pollutants, especially drug molecule pollutants.

The application discloses a kind of Co@CN nano materials, Co@CN nano materials are prepared using the following method: gelatin is weighed and dissolved in deionized water, heated and uniformly dispersed, to obtain solution A;2-methylimidazole and cobalt nitrate hexahydrate are weighed and dissolved in deionized water respectively, to obtain solution B and solution C respectively;Solution B and solution C are sequentially added to solution A, heated in water bath and stirred, to make the solution uniformly mixed, to obtain uniform purple gel after cooling;The purple gel is freeze-dried, and the solid material after freeze-drying is placed in a tube furnace, nitrogen is introduced and calcined, to obtain Co@CN.The application also discloses the application of the above Co@CN nano material in quantitative detection of 3-aminophenol (3AP), the application can quickly and quantitatively detect 3AP in environmental samples, and is convenient to operate, high in detection accuracy, and has good recovery rate, thereby solving the problem of complicated operation steps and high cost in the quantitative detection of 3AP in environmental samples by high performance liquid chromatography.

The application discloses an ion pair type pyridine bridged double aminophenoxyl alkali metal complex (I), a preparation method thereof and application of the ion pair type pyridine bridged double aminophenoxyl alkali metal complex in high-activity and high-selectivity catalysis of lactone ring-opening polymerization. The preparation method comprises the following steps: reacting a neutral ligand with a metal hydride and a quaternary ammonium salt in an organic medium, filtering, concentrating and recrystallizing to obtain the target ion pair type alkali metal complex. The ion pair type pyridine bridged double aminophenoxyl alkali metal complex is a high-efficiency lactone ring-opening polymerization catalyst, and especially, racemic lactide can be obtained to have high stereoregularity polylactide. The ion pair type pyridine bridged double aminophenoxyl alkali metal complex has the following obvious advantages: raw materials are easy to obtain, a synthesis route is simple, the ion pair type pyridine bridged double aminophenoxyl alkali metal complex has high catalytic activity and stereoselectivity for lactone polymerization, and high-regularity and high-molecular-weight polyester materials are obtained.

This invention relates to a method for synthesizing hydroquinone, a pharmaceutical and chemical intermediate. The invention comprises the following steps: (1) hydrolysis of p-chloronitrobenzene in an alkaline solution, adjusting the pH to 5-6 with acid to obtain p-nitrophenol; (2) reduction of p-nitrophenol and hydrogen under catalytic conditions to obtain p-aminophenol; (3) diazotization of a dilute acid solution of p-aminophenol with sodium nitrite; the reaction solution reacts with a dilute acid solution used for hydrolysis to obtain hydroquinone; after the reaction, solvent extraction is performed, followed by concentration, centrifugation, and drying. The reactions are carried out in a microreactor system. Compared with existing hydroquinone production processes, this invention uses continuous flow technology for continuous production, greatly improving production efficiency and saving production costs. It solves the problems of high levels of waste, low selectivity, and high purification costs associated with traditional batch processes. Furthermore, the continuous flow production process has a lower scale-up effect, easier process control, and is suitable for industrial production.

The present invention discloses a method for preparing a carbon-encapsulated porous hard carbon / Si composite negative electrode material, which belongs to the technical field of new energy materials. The present invention allows carbon nanospheres, hexadecyltrimethylammonium bromide, ammonia water, m-aminophenol and formaldehyde to act together on the porous hard carbon / Si composite material, which can effectively alleviate the volume expansion of the silicon-based material and shorten the transmission distance of lithium ions, thereby improving the cycle stability of the electrode plate. The use of the carbon-encapsulated porous hard carbon / Si composite negative electrode material of the present invention significantly increases the cycle stability of the lithium-ion battery, and the capacity does not significantly decay during high current charging and discharging, while also showing excellent rate performance.

The invention discloses a fluorescent probe for detecting hypochlorous acid as well as a preparation method and a use method of the fluorescent probe. The probe takes isophorone as a fluorescent mother group and 4-aminophenol as a recognition group of hypochlorous acid, and can detect the concentration level of hypochlorous acid in a water phase with high selectivity and high sensitivity. The probe shows orange fluorescence, under the condition that hypochlorous acid exists, hypochlorous acid and 4-aminophenol on probe molecules are subjected to a specific oxidation-hydrolysis reaction, an amino isophorone product is generated, the ICT effect of the molecules is enhanced, the emission wavelength of the probe molecules is subjected to red shift, and red fluorescence is emitted. According to the scheme, the probe obtains'ratio 'type fluorescence response on hypochlorous acid, and high-sensitivity and specific detection on hypochlorous acid is realized.

The invention provides a preparation method of a fluorescent probe and application of the fluorescent probe in detection of cysteine (Cys). According to the method, aminophenol and coumarin-6-sulfonyl chloride react to obtain an organic molecule with a simple and stable structure, and the organic molecule has a structure # imgabs0 # shown in the specification. The organic molecule is used as a probe, and quantitative detection of Cys can be realized by establishing a linear relationship between fluorescence intensity and cysteine concentration by using a fluorospectro photometer.

The invention provides a preparation method of a flame-retardant polymeric membrane material, which comprises the following steps: firstly, taking aminophenol and a halogenating reagent as raw materials, and synthesizing a phenoxy aniline monomer derivative with different substituent groups on an aniline ring through nucleophilic substitution reaction; then mixing the 3, 3 ', 4, 4'-biphenyl tetracarboxylic dianhydride with a phenoxy aniline monomer derivative with a halogen substituent on an aniline ring in an organic solvent, and carrying out condensation polymerization to form an intermediate prepolymer solution; then adding a dehydrating agent into the prepolymer solution for chemical cyclization treatment to obtain a mixed solution; and carrying out vacuum filtration and standing defoaming on the mixed solution, coating with a scraper, and carrying out high-temperature heat treatment to obtain the polymeric membrane material. The polymeric membrane material prepared by the method has excellent flame retardance and heat resistance, has the advantages of simple polymerization process, low cost, easiness in large-scale production and the like, and has a good application prospect in the fields of electronic equipment, aerospace insulation protection and the like.

The application discloses a synthesis method of 8-hydroxyquinoline, and relates to the technical fields of pesticides and organic synthesis. The method is characterized in that 8-hydroxyquinoline is prepared from o-amino phenol and propylene aldehyde as main raw materials, o-nitrophenol as an oxidant and hydrochloric acid as a catalyst. The method is suitable for industrial production of 8-hydroxyquinoline. The reaction of o-amino phenol and propylene aldehyde is realized through static mixing continuous reaction, the utilization rate of propylene aldehyde is improved, the generation of three wastes is reduced, and the method is environment-friendly. The 8-hydroxyquinoline is prepared through oxidation of an intermediate by o-nitrophenol, o-amino phenol is obtained at the same time, propylene aldehyde is continuously added to synthesize 8-hydroxyquinoline, the side reaction of excessive propylene aldehyde and the intermediate is avoided, the yield of 8-hydroxyquinoline is improved, the generation of polymers is reduced, the utilization rate of propylene aldehyde is high in the whole process, and the yield of 8-hydroxyquinoline is high.