The invention relates to a pigeon 
nest sterilization spray for boiler pigeon breeding and a preparation method thereof, and relates to the technical field of boiler pigeon breeding. The pigeon 
nest sterilization spray for boiler pigeon breeding is prepared from the following raw materials: leaf of 
magnolia officinalis, zingiber oil, leaf of Chinese ilex, folium perillae, sweet potato 
vine, 
coal ash, folium 
forsythia, 
hydrogenated palm oil, medical stone, rice 
wine lees, ardealite 
powder, ethyl 
alcohol, 
sesbania gum, an emulsifier, Chinese honeylocust fruit, compound calamine 
lotion and water. The preparation method comprises the following steps of: 
mashing plant traditional Chinese medicines, adding the mashed traditional Chinese medicines into the water to soak, heating to boil down, adding the rice 
wine lees and the ethyl 
alcohol, and filtering to obtain filtrate a; 
grinding the 
coal ash, the medical stone and the ardealite 
powder into 
powder, and after sufficiently mixing the powder with the compound calamine 
lotion, obtaining a material b; sufficiently mixing the zingiber oil and the 
hydrogenated palm oil to obtain a material c; heating the filtrate a, then adding the material b and the material c into the filtrate a, sufficiently stirring, and adding the 
sesbania gum and the emulsifier. The pigeon 
nest sterilization spray for boiler pigeon breeding, which is disclosed by the invention, is good in sterilization effect, high in response speed, high in 
efficacy, good in adhesion, long in 
efficacy acting time and good in prevention and 
treatment effect on various boiler pigeon diseases.