The invention discloses a
triamcinolone acetonide acetate injection and a preparation method thereof. The injection is prepared from 10.0g of
triamcinolone acetonide acetate,
sodium chloride which is 5.00-20 percent of the injection in a weight-to-volume ratio,
sodium merthiolate which is 0.005-0.01 percent of the injection in a volume ratio, HS-15 which is 1.00-15 percent of the injection in a volume ratio,
sodium carboxymethylcellulose which is 10.00-30 percent of the injection in a volume ratio and the balance of water for injecting. The preparation method comprises the following steps: putting
triamcinolone acetonide acetate, sodium merthiolate, sodium
chloride and
sodium carboxymethylcellulose in a
beaker according to the prescription, adding partial water for injecting, uniformly stirring, adding
activated carbon, uniformly stirring, and filtering to obtain a solution (1); weighing a proper amount of water for injecting at 30-40 DEG C, adding HS-15 which is 1.00-15 percent of the injection in a volume ratio, and uniformly stirring to obtain a solution (2); mixing the solution (1) and the solution (2), uniformly stirring, adding the water for injecting to total amount, regulating the pH value of the mixture to be 5.5-7.0 by using
acetic acid, filtering and filling and sealing. By adopting a brand-new prescription and process, a produced product has stable quality, and the safety of clinical administration can be remarkably improved.