The invention provides an atmospheric dielectric barrier discharge plasma sterilization device. The device comprises sensors (a temperature sensor, an air pressure sensor and a wind power sensor), an analysis circuit, a power supply control circuit, a plasma generation device and the like. The device adopts the principles of dielectric barrier discharge, preionization and self-inductance, so that the needed power supply voltage can be effectively reduced, the device volume is decreased, and the actual use of the sterilization device is convenient. And above all, breakdown voltage is reduced to more easily ionize gas, that is, plasma is more easily generated under the atmospheric condition, so that the density of the plasma is increased, and the sterilization efficiency of the device is improved. As thin needle tubing is adopted, the jet speed of the plasma is quickened, and the sterilization range of the plasma sterilization device is improved. In addition, the appearance design is more humanized, so that more convenience is brought to the actual operation; and for materials, heat-resistant and insulative engineering plastics with antibacterial effect after the plasma injection treatment are adopted.