47results about How to "Increase the cost of experiments" patented technology

The invention discloses a method for reconstructing a digital rock core and pore network model based on a random fractal theory. The method comprises the following steps of based on the multiple fractal features of a porous medium, performing fractal representing on a capillary pressure curve obtained by the conventional mercury intrusion method, inferring fractal expressions of random distribution density function, average value and variance by a random distribution theory, and combining the random theory and the multiple fractal theory to construct a digital rock core, so as to rapidly construct a three-dimensional micro-network model. The method has the advantages that the cost is low and is reduced; the capillary pressure curve is measured by the mercury intrusion method, the full-section rock core is used in experiment, and a micro-pore structure is fully displayed. According to the method, the computing method is simple and convenient, and the advanced method is adopted; the micro-pore structure of reservoir rock is complicated and irregular, and an extremely complicated system cannot be accurately described by the traditional classical theory, so after the method combines the multiple fractal theory and the random distribution theory, the micro-pore structure can be accurately represented, and the method is easily implemented by programming.

The invention discloses a coal and rock bore hydraulic fracture experimental apparatus, which comprises a sample device system, a confining pressure system, a fracture system, a sealing system and a monitoring system, wherein the sample device system comprises a sample cylinder, the bottom in the sample cylinder is provided with a screen drum of which the bottom is provided with a water outlet pipe, a sample is accommodated in the sample cylinder above the screen drum, and a simulated bore is formed in the sample; the confining pressure system comprises an air filling subsystem and a water filling subsystem; the fracture system comprises a fracture high-pressure water pump of which a water outlet is communicated with the simulated bore through a fracture pipeline; the sealing system comprises a sample cylinder sealing device and an experimental cylinder sealing device; and the monitoring system comprises an acoustic emission sensor arranged on an external wall of the sample cylinder. By the coal and rock bore hydraulic fracture experimental apparatus, a simulated experiment can be performed in a laboratory to investigate the change rules of crack initiation, expansion and extension in the hydraulic fracture process of a coal mine underground coal seam bore, and know a crack extending direction so as to guide field fracture; therefore, the fracture effect is greatly improved.

The invention relates to a butyl phthalide tablet and a preparation method thereof. The butyl phthalide tablet is composed of butyl phthalide solid powders and other medical troche auxiliary materials; wherein, the butyl phthalide solid powders are composed of the components with the following weight percentage: 9 percent to 30 percent of butyl phthalide, 0.01 percent to 1.2 percent of emulsifiers and 70 percent to 90 percent of cyclodextrin or cyclodextrin ramification. The troche which is made with the invention has favorable forming, stable product quality and high dissolution rate.

The invention provides a method for inverting a low permeability reservoir non-darcy flow rule by utilizing pressure monitoring data. The method comprises the following steps: measuring a bottom hole pressure value of an oil well in a period of shut-in time so as to obtain a relational value between a pressure difference and a time difference; presetting a relation between seepage velocity and pressure gradient and expressing by using a specific function; establishing and considering a mathematical model of a dynamic permeability change relationship in a default function, setting initial values of model parameters, and solving a relationship between a theoretical bottom hole pressure difference and the time difference according to a numerical model; comparing the relations between the bottom hole pressure difference and the time difference obtained by theoretical solution and actual measurement, and if the two relations meet error requirements, taking set reservoir parameters and the coefficient in the specific function as parameters obtained by interpretation during theoretical calculation; substituting the coefficient into the preset specific function, and drawing a permeability rule curve; normalizing the permeability rule curve of each well in the same block, and finally obtaining the in-situ low permeability non-darcy flow rule curve under the reservoir scale.

The present invention provides a method used for synthesizing p methoxyacetophenone with phenol. The method comprises the following steps: an acylating agent and the phenol react to prepare phenyl acetate with a catalyst; the phenyl acetate is recomposed and separated to prepare acetyl phenol; the acetyl phenol is used for preparing the p methoxyacetophenone through methoxylation. Compared with the traditional synthetic method of the p methoxyacetophenone, the method has the characteristics of low price in producing the raw materials, mild experimental conditions, less by-products in the experiment and high yield of the product.

The invention discloses a refrigeration equipment rotor compressor load excitation recognition method under the time-varying working condition. The method is characterized in that vibration testing is performed on a refrigeration equipment rotor compressor exhaust muffler opening under the time-varying condition, an actual measurement acceleration response time history signal of the rotor compressor exhaust muffler opening is obtained, and an acceleration expected response matrix is constructed; a finite element method is used for constructing a refrigeration equipment rotor compressor virtual model machine model, the virtual model machine model is applied to analyzing acceleration response of an exhaust muffler opening of the refrigeration equipment rotor compressor under the effect of white noise loads, and a transfer function matrix is obtained. Back calculation is performed on the result of vibration testing of the rotor compressor exhaust muffler opening measured point under the time-varying condition to perform load excitation of the refrigeration equipment rotor compressor under the time-varying condition, and an iterative method is adopted for eliminating errors. Refrigeration equipment rotor compressor load excitation recognition analysis under the time-varying condition is achieved, and the basis is provided for the compressor-pipeline system vibration analysis and pipeline structure reliability design, estimation and the like.

The invention discloses a 2D simulation experiment method for the flowing state of soil particles in the vibrating compaction process. The 2D simulation experiment method comprises the steps of: preparing a wooden box with a transparent front wall and detachably adjustable left and right walls; preparing a group of aluminum rods with different diameters; marking different colors on the end surfaces of the aluminum rods according to the different diameters; mixing the aluminum rods according to a certain proportion; wrapping the surfaces of the aluminum rods by using gauze and fine sand to simulate an internal friction angle; simulating cohesive force by using butter or slow-drying weak-viscosity glue; manufacturing a small loading device; paving the aluminum rods in a paper box; measuring and calculating the porosity before the experiment; starting a compaction experiment; measuring and calculating the porosity after the compaction; comparing the front and rear porosities; determining the compaction effect; observing a picture obtained by a high-speed camera; and analyzing a microscopic motion mechanism. The method can conveniently and detailedly simulate the flowing state of the soil particles in the vibrating compaction process, provides convenience for explaining the vibrating compaction mechanism from a microscopic angle, and provides a visual and effective experimental means for researching the relation between microscopic motion and macroscopic parameters in the vibrating compaction process.

The invention discloses a method to screen and culture barley transfer-gene plant with non-antibiotic of agricillin dielectric conductance in plant transfer-gene technical domain, which comprises the following steps: leading reported gene into receptor barley cell through agricillin dielectric conductance; utilizing mannose to replace antibiotic as chosen agent; screening the reverting receptor cell; adjusting the genetic reforming process of barley through phosphomannose isomerase; further-screening transfer-gene barley with chlorophenol red colouration method and PCR method; getting the end product. The barley cultivating strain conversion rate can reach 12% with agricillin dielectric conductance and can reach 100% with chlorophenol red colouration method.

The invention discloses application of a CTLA4 gene and PD1 gene humanized mouse model, and relates to the field of animal gene engineering and gene genetic modification. The CTLA4 and PD1 immune checkpoint humanized model with the BALB/c background is constructed and obtained, the model can reproduce toxic reactions of CTLA4 antibody drugs, PD1 antibody drugs and combined drugs, the problem thatother rodent mice cannot be subjected to toxicity evaluation is solved, meanwhile, the model is not as high as primate in experimental cost, and the model fills the market blank of PD1 and CTLA4 antibody safety evaluation of the rodents. The model constructed by adopting the model construction method can be used for evaluating the effectiveness of the targeted drug, screening and developing the targeted drug, evaluating the anti-tumor efficacy of the targeted drug in combination with other drugs, or researching the toxicology of the targeted drug.

The invention discloses a method for quantitative forecasting of lake basin landforms based on flow field representation. The method comprises the steps that major sand control geological factors are determined; according to structural characteristics of a research area, a basin is recovered according to a stratum burial history; a dynamic simulation system of a basin deposition sand body system is established based on basin recovery, and influences of material sources, hydrodynamic condition parameters and structural characteristic parameters on sand body distribution evolution are analyzed; according to different particle carrying modes, deposition substances are divided into cohesive silt and non-cohesive silt, and simulation representation of deposition compositions can be achieved; through simulation representations of the deposition compositions, three deposition conditions including deposition, denudation and no keeping after passing of the analyzed deposition substances are judged, and a deposition amount of the deposition substances is computed; quantitative representation of the deposition basin can be achieved; and based on simulation, the thickness of the deposition substances is overlaid to a bottom shape and finally projected to a horizontal plane, so the quantitative forecasting of the lake basin landforms can be achieved. The method has the advantages that different deposition environments can be simulated and analyzed, and the cost is low.

The invention relates to the field of metallurgical casting, in particular to a phase field simulation method for predicting nano alpha twin crystal precipitation and microscopic structure evolution in titanium alloy in a local stress state, which comprises the following steps: S1, acquiring information such as Gibbs free energy density and interface energy of two phases and phase change strain tensors of different alpha variants in a beta-to-alpha solid phase change process of the titanium alloy; s2, establishing a phase field kinetic model, and solving a phase field control equation to obtain a sequence parameter result value; s3, in the phase transformation process under a certain supercooling degree, changing the stress load orientation and size, and obtaining different microstructure morphology information; and s4, performing visualization processing on corresponding microstructure evolution results under different input conditions, and clarifying an influence rule of a local stress state on a nano alpha twin crystal nucleation and evolution process. According to the method, the beta-to-alpha conversion process in the titanium alloy can be reproduced, and a visual prediction method is provided for the microstructure form and the evolution process of the titanium alloy under the thermal-mechanical coupling effect.

The invention provides a metal processing mold having automatic feeding and discharging functions. The metal processing mold comprises a lower pressing die, a screw rod, a bearing seat, a male die, awork clamping board, a servo motor, a rotating shaft, an electric telescopic rod and an electromagnet, wherein the screw rod is arranged in the lower pressing die; the bearing seat is mounted on the screw rod; the male die is fixed to the upper end surface of the bearing seat, and is arranged on the upper end surface of the lower pressing die; the work clamping board is assembled on the upper endsurface of the male die, and through the design, a fine adjustment function is realized; the servo motor is fixed to the front end of the lower pressing die; the rotating shaft is mounted at the upperend of the servo motor; the electric telescopic rod is fixed at the right end of the rotating shaft; the electromagnet is mounted at the right end of the electric telescopic rod; and the electric telescopic rod and the electromagnet are arranged above the lower pressing die, and through the design, automatic feeding and automatic discharging can be performed. According to the metal processing mold disclosed by the invention, the fine adjustment function is realized, the automatic feeding and discharging functions are realized, and the metal processing mold is high in practicality, good in safety and high in reliability.

Hydrogen peroxide eliminates the DTT interference method of nucleic acid constant temperature amplification and detection of mercury ions. The recognition sequence containing the mismatch site and the primer and template that triggers nucleic acid constant temperature amplification is mixed at a concentration of 100nM in equal volumes, and the recognition sequence is combined with the target to be detected. Mercury ions in mercury-containing solution can then form a stable hybrid structure that can be recognized by polymerase; mix the stable hybrid structure with hydrogen peroxide solution, amplification substrate, DNA polymerase KF, SYBR GreenⅠ, and amplification reaction buffer Under the action of polymerase, the amplification reaction is triggered to generate double-stranded DNA; SYBR Green I can specifically bind to double-stranded DNA molecules and emit fluorescent signals at the same time; the amplified sequence is characterized by melting curve and agarose gel electrophoresis , it is confirmed that hydrogen peroxide eliminates the interference of DTT, and the invention eliminates the interference of DTT on the detection of trace mercury ions, has good system compatibility, is easy to operate, and does not depend on complex equipment.

The invention belongs to the technical field of reactor simulation experiments, and particularly relates to an experimental model for a sodium-cooled pool type fast reactor natural circulation experiment. The experimental model comprises a cylindrical shell formed by sequentially connecting an upper sealing head, an upper cylinder body, a lower cylinder body and a lower sealing head from top to bottom in a sealed mode, the upper sealing head and the upper cylinder body form a hot pool, and the lower cylinder body and the lower sealing head form a cold pool. The experimental model also comprises a simulated reactor core located in the center of the shell, a central measuring column simulation part located above the simulated reactor core, a large grid plate header simulation part located below the simulated reactor core, a DR type heat exchanger simulation part arranged in the hot pool, a DL type heat exchanger simulation part arranged in the cold pool, and an M-type heat exchanger simulation part arranged between the hot pool and the cold pool in a penetrating manner. Working media in the cold pool can be powered by an external circulating pump to sequentially enter the large grid plate header simulation part and the simulation reactor core to enter the hot pool, and then return to the cold pool again after exchanging heat with the M-type heat exchanger simulation part.