The invention discloses a medical hyperbaric oxygen chamber therapy system, which comprises a hyperbaric oxygen chamber, and an oxygen supply system, an air supply system and a waste oxygen exhaust system which are connected with the hyperbaric oxygen chamber, and also comprises a computer monitoring and control system, wherein the computer monitoring and control system comprises a controller and a computer terminal which is connected with the controller and controls the controller, and the controller is respectively connected with the hyperbaric oxygen chamber, the oxygen supply system, the waste oxygen exhaust system and the air supply system. The oxygen supply system, the air supply system and the waste oxygen exhaust system of the hyperbaric oxygen chamber are controlled by the computer monitoring and control system, and oxygen pressure, air pressure, pressurization rate, exhaust rate, temperature and other parameters in the hyperbaric oxygen chamber are precisely monitored, so that the hyperbaric oxygen environment in which a patient is positioned smoothly changes, and does not suddenly change, and thus the possibility of generating barotrauma is reduced, and an oxygen concentration sensor controls intake and outtake pneumatic diaphragm valves to regulate the environment in the chamber based on actual pressure and temperature so as to achieve the best therapeutic effect.