31results about How to "Solve industrialization problems" patented technology

The invention relates to a bone china with high resistance to heat shocks and a manufacture method thereof. The raw material components of the bone china stock and the weight percentages are: 9 to 12 of quartz, 7 to 10 of feldspar, 11 to 14 of greensand, 4 to 7 of Longyan clay, 5 to 8 of china clay, 4 to 7 of kibushi clay, 42 to 46 of bone coal and 7 to 10 of bentonite; the raw material components and the weight percentages of glaze material are: 5 to 8 of the quartz, 2 to 5 of the bentonite, 3 to 6 of Suzhou clay, 50 to 53 of model one fused block and 34 to 37 of model two fused block; the bone china has the resistance to heat shocks that no crack occurs during the heat change in the water with the temperature of 200 to 20 DEG C for once. The manufacture steps are as follows: preparing stock paste, preparing glaze paste, roller forming, grouting and forming, biscuit firing, glazing, glaze firing and decorating firing. The enamel layer of the invention has the advantages of large elasticity, good toughness and mechanical property. The raw material ingredients have no lead and zero radioactivity, which are green. The manufacture method is scientific and reasonable, and the product has the resistance to heat shocks that no crack occurs during the heat change in the water with the temperature of 200 to 20 DEG C at one time.

The invention discloses a method for preparing alpha-androstanol, comprising the following steps: liquid fermentation is carried out on tuber bacterial strain to obtain zymotic fluid or mycelium containing the alpha-androstanol. The invention also discloses a method for detecting content of the alpha-androstanol in the zymotic fluid or the mycelium. In the invention, tuber liquid fermentation is adopted to produce alpha-androstanol, compared with chemosynthesis, the method of the invention has the advantages of low cost, short cycle, easy operation controllable quality and capability of preventing chemical residue, etc.

The invention discloses a sulfur-substituted podophyllum derivative and a bioconversion, separation and purification method thereof. The sulfur-substituted podophyllum derivative with antitumor activity, shown as Formula (I) or (II), is obtained by modifying the molecular structure of podophyllotoxin or 4'-demethylepipodophyllotoxin through a bioconversion method. Preliminary study on in-vitro tumor cytotoxicity shows that the sulfur-substituted podophyllum derivative disclosed by the invention has stronger inhabitation action on the growth of tumor cells such as BGC823, HepG2, A549 and the like, and thus can be used as an antitumor compound to achieve a potential drug development value. According to the invention, the podophyllotoxin and the 4'-demethylepipodophyllotoxin are converted into the sulfur-substituted podophyllum derivative by using a bioconversion method, and therefore, the sulfur-substituted podophyllum derivative has the advantages of low cost and E-factor, simplicity in operation, easiness for culturing, controllable quality, capability of effectively preventing chemical residuals and the like.

The invention discloses a method for transforming podophyllotoxin into 4-(2,3,5,6-tetramethylpyrazine-1-group)-4'-demethylepipodophyllotoxin, comprising the following steps of: (1) adding podophyllotoxin into a liquid fermentation medium, and carrying out biotransformation by inoculating second-class liquid seeds of humic soil fungi; (2) separating and purifying the product from the Step (1), followed by adding into the liquid fermentation medium, carrying out biotransformation by inoculating second-class liquid seeds of podophyllum taxa endophytes; then continuously carrying out biotransformation by adding ligustrazine, and collecting the transformation product. The invention also discloses a method for purifying 4-(2,3,5,6-tetramethylpyrazine-1-group)-4'-demethylepipodophyllotoxin from the above product and a method for detecting the content of 4-(2,3,5,6-tetramethylpyrazine-1-group)-4'-demethylepipodophyllotoxin. According to the invention, the molecular structure of podophyllotoxin is modified by the biotransformation method, which has advantages of mild reaction condition, low E-factor, quality controllability and simple separation process.

The invention relates to ganoderma spore powder refined polysaccharide with significant auxiliary anti-tumor activity and a preparation method and application thereof, and belongs to the field of medicinal-fungus extraction and separation and the field of drug and food application development. The refined polysaccharide is mainly prepared from heteropolysaccharide composed of mannose, glucose, galactose and fucose according to the molar ratio of 1: (40-50): (4-5.5): (1.5-2), the purity of the refined polysaccharide is greater than 80%, and the weight-average molecular weight is 160-200 KD. Thepreparation method of the ganoderma spore powder refined polysaccharide includes the steps of using hot water for dynamic extraction, removing residues by combining sedimentation and rough filtration, conducting refined filtration and clarification, removing impurities through ultrafiltration-membrane concentration, and drying through spray or airing through alcohol precipitation. The preparationmethod of the ganoderma spore powder refined polysaccharide is environmentally friendly and smart, saves energy, can solve industrialized difficulties and has significant scale advantages, prepared products meet the requirements, about the safety, availability, controllability and stability, in a drug and medicine quality controlling system. The ganoderma spore powder refined polysaccharide has significant functional activity at the auxiliary anti-tumor aspect and can be used for developing tumor prevention and treating drugs, and development of food and healthcare products in related fieldscan be carried out.

The invention discloses a medium for cultivating male stone pine and its application. The medium is composed of raw material components in the following proportions: MS medium: sucrose: carrageenan: carrot puree: peptone: banana puree: activated carbon=1L : 23~27g: 5~7g: 18~22g: 1.8~2.2g: 90~110g: 0.8~1.2g, wherein each liter of MS medium contains 6-BA 1.8~2.2mg, NAA 0.8~1.2mg and KT 0.15~0.25mg. The culture medium of the specific composition distribution method of the present invention can realize the rapid propagation of male stone pine seedlings in one step.

The invention discloses preparation, purification and content detection methods for cerebroside, which belong to the field of cerebroside preparation. The method for preparing the cerebroside comprises the step that: biological fermentation is carried out on tuber strains to obtain mycelium containing the cerebroside. In the method, the culture conditions and the culture medium composition in each step of liquid fermentation are optimized and screened, and the yield of the cerebroside is improved to the furthest degree. The invention also discloses a method for separating and purifying the cerebroside from the mycelium and detecting the content of the cerebroside. Tuber liquid is used for producing the cerebroside through fermentation. Compared with the existing cerebroside production method, the method has the advantages that the cost is low, the period is short, the operation is simple, the quality is controllable, the separation process is simple, and the like.

The invention specifically discloses a milk replacer for squabs and a preparation method for the milk replacer, and solves the problem of restrictions of lactation of conventional 1 to 10-day aged squabs to squab intensification and industrialization. The milk replacer for the squabs is prepared from the following air-dried solid raw materials in parts by weight: 250 to 300 parts of egg powder, 150 to 200 parts of fish meal, 150 to 200 parts of soybean meal, 100 to 150 parts of whole milk powder, 80 to 100 parts of vegetable oil, 50 to 80 parts of corn gluten meal, 40 to 80 parts of lactic acid powder, 6 to 8 parts of calcium hydrogen phosphate, 2 to 3 parts of edible salt, 0.8 to 1 part of composite trace element, 0.6 to 1 part of composite vitamin and 0.1 to 0.2 part of an antioxidant. The prepared milk replacer is nutritionally balanced, high in palatability and easy to digest and absorb and accords with gastrointestinal digestion characteristics of the squabs, and has the advantages of convenience in storage and preparation and capability of meeting squab intensive-feeding production requirements, and requirements of 1 to 10-day aged squabs on nutrition are met.