50results about How to "No residual risk" patented technology

The invention relates to an alga extract product with an antibacterial function, an antibacterial agent including the alga extract product, a composition, and a preparation method of the composition, and belongs to the technical field of antibacterial detergents. The composition contains the algal antibacterial agent, a surfactant, an antioxidant and water, and especially the algal antibacterial agent is selected from an alga extract product-anionic surfactant complex. The invention also discloses the preparation method and a use of the composition. Above detergents provided by the invention have the characteristics of no pollution to environment, safety and mildness to people, greenness and environmental protection, and facilitation of the safety of environment and human life.

The invention discloses a preparation method of high-efficiency cyhalothrin nano-pesticide, belonging to the technical field of preparation of agricultural chemicals. The preparation method is characterized in that an amphiphilic copolymer is adopted and is self-assembled in an aqueous solution to form a nano-sized micelle with an obvious core-shell structure; the nano-pesticide is obtained by physical actions of an organic solvent and polyvinyl alcohol. The preparation method disclosed by the invention is simple and convenient; raw materials are easily obtained; a used solvent is water, so the pollution is small and the cost is low; the used amphiphilic copolymer has good environmental compatibility, biodegradation and no residual risks; in addition, a degraded product can be absorbed and utilized by crops; the nano-pesticide has the advantages of relatively small and relatively uniform particle size, relatively good permeability and certain slow release effect; the lasting period of pyrethroid pesticides is prolonged, and the using dose of the pesticide is reduced.

The invention relates to ganoderma spore powder refined polysaccharide with significant auxiliary anti-tumor activity and a preparation method and application thereof, and belongs to the field of medicinal-fungus extraction and separation and the field of drug and food application development. The refined polysaccharide is mainly prepared from heteropolysaccharide composed of mannose, glucose, galactose and fucose according to the molar ratio of 1: (40-50): (4-5.5): (1.5-2), the purity of the refined polysaccharide is greater than 80%, and the weight-average molecular weight is 160-200 KD. Thepreparation method of the ganoderma spore powder refined polysaccharide includes the steps of using hot water for dynamic extraction, removing residues by combining sedimentation and rough filtration, conducting refined filtration and clarification, removing impurities through ultrafiltration-membrane concentration, and drying through spray or airing through alcohol precipitation. The preparationmethod of the ganoderma spore powder refined polysaccharide is environmentally friendly and smart, saves energy, can solve industrialized difficulties and has significant scale advantages, prepared products meet the requirements, about the safety, availability, controllability and stability, in a drug and medicine quality controlling system. The ganoderma spore powder refined polysaccharide has significant functional activity at the auxiliary anti-tumor aspect and can be used for developing tumor prevention and treating drugs, and development of food and healthcare products in related fieldscan be carried out.

The invention discloses a full-soluble edible mushroom protein and a preparation method thereof. The full-soluble edible mushroom protein is prepared by the following steps: unmodified edible mushroom protein is expanded under an alkaline condition, and then acid is added to adjust the edible mushroom protein to be neutral. According to the preparation method, the primary structure of the protein is not changed, the nutritional value of the protein can be reserved to the maximum extent, the obtained edible mushroom protein is free of exogenous additive components, the acceptance degree of consumers is improved to the maximum extent, reasonable utilization of edible mushroom byproducts is achieved, and resource waste and environmental pollution are effectively avoided.

The invention relates to a making method of instant fresh stretched noodles, and belongs to the technical field of food making. A technical problem to be solved is providing the making method of the instant fresh stretched noodles. The method can guarantee unique mouthfeel and chewiness of present fresh stretched noodles, and also can meet people's fast easing demands, so the noodles can be immediately stretched and eaten without tedious dough kneading when people want to eat the stretched noodles. A technical scheme adopted in the invention to realize the above purposes is characterized in that the method comprises the following steps: uniformly mixing flour, edible salt, eggs and water, and kneading until smoothness to form dough; fermenting the dough, kneading once every 10-15min in the fermentation process, kneading the fermented dough to form circular elongated noodles, uniformly smearing the surfaces of the elongated noodles with edible oil, putting the elongated noodles in a dough holder, sealing, putting the sealed noodles in a refrigerator, refrigerating to obtain semi-finished fresh stretched noodles, taking the semi-finished fresh stretched noodles out of the refrigerator when people want to eat the noodles, unfreezing, and stretching the unfrozen semi-finished fresh stretched noodles to form the instant fresh stretched noodles.

The invention discloses a crystal form of linagliptin and a preparation method thereof. For the crystal form, X-ray powder diffraction, expressed in 2 theta angle and using the alpha radiation of Cu-K(copper-potassium), has diffraction peaks at 23.1 plus or minus 0.2 degrees, 23.5 plus or minus 0.2 degrees, 24.6 plus or minus 0.2 degrees and 27.1 plus or minus 0.2 degrees. The preparation methodof the crystal form of the linagliptin includes the steps of preparing linagliptin solid into a suspension in a solvent and stirring, adding purified water therein after heating to 30-70 DEG C, cooling down to 0-20 DEG C and growing crystal at constant temperature for 0.5-2 hours, filtering crystal slurry, and drying to constant weight. The crystal form of the linagliptin has the advantages of good stability, high safety, and suitablility for industrial production.

The present invention provides an absorbable semi-flowing cross-linked polypeptide biological surgical bleeding-stopping substance, which comprises a gelatin and a cross-linking agent, wherein a cross-linking agent is added to a gelatin solution to make high-reactivity amino acid side chains react with each other so as to form a cross-linking structure, and iron-calcium ions are added to increase the cross-linking degree so as to finally form the three-dimensional network cross-linked macromolecular polypeptide. According to the present invention, the absorbable semi-flowing cross-linked polypeptide biological surgical bleeding-stopping substance can be safely absorbed by human tissues, has characteristics of semi-fluidity, viscosity and adhesion, can promote the coagulation process of human body through physical and chemical principles, can rapidly stop bleeding, can treat surgical bleeding in the case of no damage on tissues so as to improve the convenience and the flexibility of surgical hemostasis and improve the safety and the effectiveness of surgical hemostasis, and can achieve the satisfactory bleeding-stopping effect in the cases of multi-point bleeding, large-area errhysis, bleeding in the narrow lacuna, hidden bleeding point or difficultly distinguished bleeding point, and bleeding difficultly operated and controlled by the existing bleeding-stopping methods.

The invention discloses a degradable meninx repairing material and a preparing method thereof. The degradable meninx repairing material is prepared from a bacterial cellulose film with gaps, and the bacterial cellulose film is oxidized bacterial cellulose with C6-site hydroxyl oxidized into carboxyl. The preparing method of the degradable meninx repairing material includes the following steps that 1, the gaps are formed in the bacterial cellulose film, and the bacterial cellulose film with the gaps are obtained; 2, a group oxidizing reaction is carried out on the bacterial cellulose film with the gaps obtained in the first step, and the degradable meninx repairing material can be obtained. The meninx repairing material has the synechia preventing function and the cerebrospinal fluid leakage preventing function, and can be gradually degraded while guiding auto-defect repairing of cerebral dura mater tissue.

The invention belongs to the technical field of coatings, and discloses awater-based polyester copolymer and a preparation method and application thereof.The water-based polyester copolymer is mainly prepared from the following components: polyol, polyacid and an environmentally friendly catalyst. The polyol includes spiro diols and diols with no less than 5 carbon atoms in the main chain. The polyacid includes aromatic polyacid, sulfonic acid group-containing dibasic acid (ester), fatty acid and alicyclic acid; the environmental protection catalyst is prepared by complexing reaction of titanate, silicate and amine compound; 70-100% of the total carboxyl end groups in the water-based polyester copolymer are derived from fatty acid and/or alicyclic acid end carboxyl groups. After the water-based polyester copolymer is used in the preparation of water-based coatings, the cured coating has excellent processability, boiling water resistance and stability.

The invention discloses a primer-free blocking glue and its preparation method. Through adding PVOH product with better blocking property in PVDC latex, the blocking property is improved (<=2cc/m2.24hr), and the polymerization technique is further adjusted; finally, the primer-free PVDC latex is prepared; on the basis of guaranteeing good blocking effect, the film primer coating process is reduced, generation of organic solvent in the production process is avoided; besides, there is no risk of solvent residue.

The invention relates to use of a lentinula edodes dietary fiber extract in the pharmaceutical field, in particular to application of the lentinula edodes dietary fiber extract in preparation of preparations for treating and/or preventing liver injury-related diseases caused by high fat diet. The lentinula edodes dietary fiber extract not only can obviously contribute to the recovery of the dominant flora structure in the intestinal tract and is beneficial to the diversification of the flora, but also shows obvious treatment and/or prevention effect on the liver injury-related diseases causedby high fat diet; the lentinula edodes dietary fiber extract can effectively inhibit the expression of inflammatory factors, effectively alleviates the deterioration of inflammation, improves variousphysiological and pathological indicators related to immunity, and can be used in various fields such as medicines and health care products, thus having great economic and social values.

The invention provides hyaluronic acid composite gel for filling lacrimal ducts and a preparation process of the hyaluronic acid composite gel. The composite gel is prepared by crosslinking medium-molecular-weight sodium hyaluronate, low-molecular-weight sodium hyaluronate and recombinant collagen, wherein the mass percent of the medium molecular weight sodium hyaluronate and the mass percent of the low molecular weight sodium hyaluronate in the composite gel are both 1.2-2.0%, the mass percent of the recombinant collagen in the composite gel is 0.4-0.7%, and the balance of the composite gel is the phosphate buffer solution. According to the preparation method, crosslinking is carried out through physical means of rapid heating, heat preservation and rapid cooling. According to the composite gel disclosed by the invention, the medium-molecular-weight sodium hyaluronate, the low-molecular-weight sodium hyaluronate and the recombinant collagen are matched, so that the filling effect can be ensured, the maintaining time of the filling effect can be prolonged, the Tyndall effect can be effectively avoided, the safety is high, and skin nutrition can be repaired and supplemented; the physical crosslinking method of rapid heating-heat preservation-rapid cooling does not need a crosslinking agent and has no residual risk.

The invention relates to use of a dietary fiber extract from oudemansiellara maflbes in the field of pharmacy, in particular to use of a dietary fiber extract from the oudemansiellara maflbes in preparation of preparations for treating and/or preventing liver injury-related diseases caused by high fat diet. The dietary fiber extract from the oudemansiellara maflbes not only can significantly contribute to the repair of liver injury caused by the high fat diet, but also shows obvious therapeutic and/or preventive effects on the liver injury-related diseases; for example, the dietary fiber extract from the oudemansiellara maflbes effectively inhibits the expression of inflammatory factors, effectively alleviates the deterioration of inflammation, improves various physiological and pathological indicators related to immunity, and can be used in various fields such as medicines and health care products, thus having great economic and social values.

The invention relates to a preparing method of a carotenoid preparation. The method comprises the following steps: 1) adding carotenoid and other raw materials into purified water, stirring, dissolving and emulsifying evenly; 2) transferring the materials prepared in the step 1) into a grinding device, grinding, sampling and measuring the particle size of 0.01-2 [mu]m; and 3) carrying out spray drying on the obtained material with the particle size of 0.01-2 [mu]m in the step 2), embedding with starch, and carrying out secondary granulation, to obtain carotenoid microcapsules. In the method, residues of an organic solvent on the microcapsules are effectively avoided, and no residual risk of the solvent exists; and preparation does not need to be carried out under conditions of high temperature and high pressure, the yield is improved, the process is simple, the preparation conditions are improved, the production process is optimized, and the industrialized production of the product isfacilitated.

The invention discloses a spotted cutworm isotropic nano-fiber preparation and a preparation method thereof and belongs to the technical field of agrochemical preparation. The spotted cutworm isotropic nano-fiber preparation is polymer nano-fiber containing spotted cutworm sex pheromone. The preparation method provided by the invention is simple and convenient and is available in raw material. According to the preparation method, a used polymer has good environmental compatibility, is bio-degradable and does not have a residue risk; the prepared nano-fibers are high in mechanical strength, relatively small and uniform in particle size and relatively high in drug loading capacity, has a certain sustained release effect, prevents sprayed fields from being scoured by air flows and rainstorms,reduces the dosage of the spotted cutworm sex pheromone, prolongs the sustained release persistent period of the spotted cutworm sex pheromone, and can perform effective isotropy on the spotted cutworm at the same time. Reference for comprehensively treating the spotted cutworm is provided.

The invention discloses a dapoxetine hydrochloride monohydrate and a preparation method thereof, a composition containing the dapoxetine hydrochloride monohydrate, and uses of the composition in preparation of drugs for treatment of sexual dysfunction, wherein the dapoxetine hydrochloride monohydrate is represented by a formula I. According to the present invention, the dapoxetine hydrochloride monohydrate overcomes the disadvantages of easy moisture absorption, poor stability, high requirements on storage conditions and difficult long-term preservation of the existing crystal form or the amorphous form of dapoxetine hydrochloride, and is suitable for industrial scale-up and preparation production. The formula I is defined in the specification.

The invention discloses a glycyrrhiza glabra extract and a preparation method and application thereof. The preparation method comprises the following steps: S1, selecting roots and rhizomes of fresh glycyrrhiza glabra, then putting the selected roots and rhizomes of the fresh glycyrrhiza glabra into an ultrasonic cleaning machine, cleaning the roots and rhizomes of the fresh glycyrrhiza glabra through the ultrasonic cleaning machine, and cleaning impurities and pesticides on the surfaces of the roots and rhizomes of the fresh glycyrrhiza glabra; and S2, then taking out the cleaned roots and rhizomes of the fresh glycyrrhiza glabra, putting the roots and rhizomes into an electrothermal blowing drying box, and drying the cleaned roots and rhizomes of the fresh glycyrrhiza glabra through theelectrothermal blowing drying box. The process is simple to operate, industrial production is easy to realize, and the obtained product is clear in component, free of solvent residue risk, and safe and effective when being applied to series of cosmetic products.

The invention discloses a method for preparing phosphatidylserine without an organic solvent, which comprises the following steps: adding an enzyme-containing aqueous solution into soya bean lecithin and L-serine serving as raw materials, homogenizing and mixing for reaction, adding water into the reaction solution after the reaction is ended to dissolve the L-serine, centrifugally separating to obtain a water phase and a precipitate, washing the precipitate with water, centrifugally separating to obtain a water phase and a precipitate, and drying to obtain the phosphatidylserine. Combining water phases, concentrating through membrane filtration to recover L-serine, combining precipitates, and freeze-drying in vacuum to obtain a phosphatidylserine product. According to the method, phosphatidylserine is synthesized from soybean lecithin through an enzyme synthesis method, no organic solvent is used, the process is simple, energy consumption is low, and industrial production is easy to achieve.

The invention discloses a lactobacillus fermentum PV22 with an anti-virus capacity, and application of the lactobacillus fermentum PV22. The Lactobacillus fermentum PV22 is collected in the GuangdongMicrobial Culture Collection Center (GDMCC) on December 18th, 2020, the collection address is 5th floor, No.59 building, No.100, Xianlie Middle Road, Guangzhou, Guangdong Province, and the collectionnumber is GDMCC No.61376. The lactobacillus fermentum PV22 can obviously lower virus infectivity, obvious virus-antagonizing efficacy can be achieved in short time, in addition, an anti-virus effect is increased along with prolonging of action time, and a post-infection survival rate of a virus infection cell can be improved. Therefore, the lactobacillus fermentum (L.fermentum) PV22 can be appliedto preparation of products (such as foods, medicines, health care products and the like) used for preventing or treating virus infection, and has a huge application prospect.