The invention belongs to the technical field of active
peptide preparation, and particularly relates to an active
collagen peptide with an immunoregulation function and a preparation method and application thereof. The active
collagen peptide with an immunoregulation function is prepared by using a method of performing composite enzymolysis and separating and collecting specified collection liquid by using a
chromatographic column, and a new thought is provided for improving the
immunity; the prepared active
collagen peptide can significantly improve the proliferative activity, phagocytic ability and NO
secretion amount of RAW264.7 cells and change the
cell morphology, has an important regulation effect on immune balance
recovery of
immunosuppression model mice, and can regulate the problem of low
immunologic function of mice induced by
cyclophosphamide, regulate immune balance and improve the body
immunity.