The invention relates to a manufacturing technique of bone protein peptide calcium, comprising the following steps: (1) beast and bird bone is made into minced bone which is used as hydrolyzing substrate; (2) pH value is adjusted to 5-7, ossein enzyme is firstly used, common proteinase is then used for hydrolyzing, and temperature is risen for killing enzyme; (3) bone protein hydrolyzing liquid is filtered, the filtered liquid is dried after membrane filtration, and bone protein peptide powder can be obtained; filter residue is dissolved by adding acid, then the solution is filtered and dried, and bone calcium phosphate powder can be obtained; at last, the bone protein peptide powder and the bone calcium phosphate powder are mixed to obtain the bone protein peptide calcium powder. The invention has the following advantages: firstly, the absorption for a human body is easy, and the calcium-phosphorus ratio is 2 to 1 which is reasonable, and the bone protein peptide calcium is favorable calcium enriching product; secondly, the nutrition is abundant, in the bone protein peptide calcium of the product, the content of total protein is 10.38 percent, the content of the bone protein peptide is 8.56 percent, the content of the calcium is 6.16 percent, and the content of the phosphorus is 2.73 percent.