47results about How to "Has a long-lasting effect" patented technology

The invention discloses an anthocyanin phospholipids compound and a preparation method thereof, comprises an anthocyanin phospholipids compound and a preparation method thereof, and belongs to the field of medicaments and health-care products. The components of the anthocyanin phospholipids compound comprise anthocyanin and phospholipids, wherein the weight ratio of the anthocyanin to the phospholipids is 1:1-20; and the preparation method adopts an organic solvent with a small dielectric constant for dissolving a mixture of the anthocyanin and the phospholipids and prepares the anthocyanin phospholipids compound through solvent evaporation and other technical processes. The anthocyanin phospholipids compound has the advantages of lipid solubility, easy absorption, high bioavailability, emulation formulation, and the like.

The invention relates to the technical field of pharmaceutical preparation, in particular to a percutaneous absorption patch containing gestodene and (or) estrogen, and also discloses the preparation method. The patch style medicine of the invention can be released by constant rate for a long time.

The invention provides a method for producing a long-acting compound fertilizer by utilizing waste resources. The raw materials comprise the following components by weight percent: 48% of yellow phosphorus slag, 32% of waste edible mushroom bag material, 14% of humic acid and 6% of caustic soda. The method comprises the following steps: 1) grinding the yellow phosphorus slag with a ball mill to 200 meshes; 2) grinding the waste edible mushroom bag material to 100 meshes; 3) mixing humic acid and caustic soda, adding clean water of which the addition amount is twice the mixed total amount in the mixture, stirring, heating to 95 DEG C to obtain paste for later use; 4) stirring the materials evenly; 5) placing the mixed materials in a granulating disc to granulate; 6) screening the particles, re-granulating the particles of which the particle size is more than 4.5mm; and 7) drying the particles to obtain the finished product. The method uses the waste resources as raw materials; as the yellow phosphorus slag contains active silica, the photosynthesis and bacteria resistance of the crop can be effectively increased and the nitrogen and phosphorus nutrients can be fully utilized; and as the waste edible mushroom bag material contains rich organic matters and various nutrient elements, the produced compound fertilizer has high fertilizer efficiency, the soil can be improved effectively, the cost is low and the long-acting compound fertilizer provided by the invention is a low-investment long-acting compound fertilizer.

The invention relates to a single tower cable-stayed bridge with an unsymmetrical plane broken line arranged bridge deck and a building method thereof, which belong to the cable-stayed bridge with the unsymmetrical plane broken line arranged bridge deck and the building method thereof. The single tower cable-stayed bridge with the unsymmetrical plane broken line arranged bridge deck comprises an unsymmetrical pyramid-type bridge tower and bridge piers, wherein the bridge piers are arranged at the two ends of the bridge; two ends of a long bridge deck and a short bridge deck are fixedly connected with the unsymmetrical pyramid-type bridge tower and the bridge piers, respectively; two ends of inhaul cables are respectively connected with tower columns of the unsymmetrical pyramid-type bridge tower and the bridge deck; the two sides of the long bridge deck or the short bridge deck are fixedly connected with arc damping cables, respectively. According to the invention, the single tower cable-stayed bridge with the unsymmetrical plane broken line arranged bridge deck can be used for hydraulic wading cable-stayed bridge structural designs; the technology of the single tower cable-stayed bridge is simple and convenient; the broken line angle of the single tower cable-stayed bridge can be set at 0-30 degrees according to needs; as the damping cables are arranged, the seismic capability of the cable-stayed bridge is improved, bridge deck slab displacement is also effectively limited, the stability of the bridge deck in use is improved, and an inhaul cable protecting method has a long-acting effect.

The invention relates to a carbidopa-levedopa sustained-release dropping pill for the treatment of Parkinson's disease and a preparation method thereof. The invention aims to solve the insufficiencies of an oral preparation, and provides a carbidopa-levedopa sustained-release dropping pill, which has advantages of high bioavailability, rapid effectiveness, long action time, low frequency of drug taking, convenient administration, little toxic or side effect, convenient storage and transportation, and suitability for oral administration, and the preparation method thereof.

The invention relates to an antibacterial algae adhesion coating for concrete. The antibacterial algae-resistant coating for the concrete is prepared from sodium silicate, potassium silicate, a surfactant, OIT, Diuron, a polymer emulsion, a defoaming agent, a coalescing agent, superfine cement powder, an early strength agent and a water reducing agent. The antibacterial and algae-resistant coating for the concrete acts on the surface of the concrete in an over-spraying construction mode, and a compact crystal structure is generated on the surface of the concrete, so that a compact nano protective layer is formed, the smoothness is high, and the adhesion of molds and algae can be effectively inhibited, so that the concrete has the characteristics of resisting common germs, molds and algae, inhibiting drug-resistant germs, resisting bacteria and algae and the like. The efficient and lasting functions are realized.

The present invention discloses a compound feed additive for improving piglet production performance and relates to the technical field of breeding. The compound feed additive is prepared by fermenting traditional Chinese medicine superfine powder with probiotics; and the traditional Chinese medicine superfine powder comprises the following traditional Chinese medicines in parts by weight: 15-25 parts of radix astragali, 15-25 parts of haws, 12-18 parts of fried bighead atractylodes rhizome, 12-18 parts of dried orange peels, 15-20 parts of cortex magnoliae officinalis, 15-20 parts of fringedpink and 10-15 parts of honey-fried licorice root. The present invention also provides a preparation method and an application of the compound feed additive. The used compound feed additive can greatly improve immunity and resistance of bred animals, reduces incidence, thus improves production performance, is also a pure natural preparation, has no tolerance, has a long-acting effect, is stable inquality and low in cost, can replace uses of anti-microorganism drug feed additives and chemically synthesized growth promoters, and is safer and more environment-friendly.

The invention relates to a preparation method of a novel goat sperm in-vitro agonist. The method is characterized by comprising the following steps: (1) cleaning adult goat testes; (2) cutting the tunica albuginea of the testes; (3) using tweezers to clamp out tissues for washing; (4) adding a DMEM basic culture solution after digestion; (5) performing filtering and centrifuging, adding a buffer solution, and performing centrifuging; (6) adding a DMEM basic culture solution, taking cell suspension, performing centrifuging, and collecting cells; (7) adding PBS, performing centrifuging, and then adding a DMEM basic culture solution for culture; (8) carrying out cell passage, performing culturing for 8 hours, and performing storing to obtain a basic liquid I; (9) adding bill goat serum (EGS), calcium ionophore (IA), caffeine, pentoxifylline (PF), 17alpha-20beta-dihydroxyprogesterone (DHP) and heparin into a DMEM basic culture solution, and performing full and uniform mixing to obtain basic liquid II; and (10) uniformly mixing the basic liquid I with the basic liquid II according to a ratio of 5:1 to obtain the novel goat sperm in-vitro agonist. The agonist has the advantages of good application effect, low cost and easy processing and production.

The invention relates to a preparation method of an agonist for improving fish sperm motility. The method comprises the following steps: (1) taking the fish gonads in a development stage V; (2) separating interstitial cells of the fish gonad; (3) adding an HHBS cell culture solution; (4) adding 3mL of hyaluronidase into a centrifugal tube, adding 5 mL of the cell culture solution after concussion,and obtaining a supernatant by centrifugation; (5) filtering the supernatant with a cell sieve; (6) respectively adding DMSO, glutathione and cysteine to the filtered cell supernatant, blowing, beating, uniformly mixing, and carrying out cryopreservation at the temperature of -20 DEG C so as to obtain the product. The method has the advantages of good application effect, low cost and easiness inprocessing and production.

The invention relates to a preparation method of a biomass long-acting heavy metal passivator, and belongs to the technical field of soil remediation. The method comprises the following steps: firstly, taking sugarcanes rich in sugar as a raw material, performing juice squeezing to obtain sugarcane juice, and concentrating the sugarcane juice to obtain concentrated syrup; mixing corn starch with the concentrated syrup to obtain a biomass sugar adhesive; then, sintering rice husks as a raw material, and mixing the rice husk ash with calcium carbonate for reaction to obtain a prefabricated passivator; mixing the biomass sugar adhesive with bacillus subtilis to obtain bacteria-containing adhesive; and finally, bonding the prefabricated passivator by utilizing the bacteria-containing adhesive,granulating the prefabricated passivator, and performing drying to obtain the biomass long-acting heavy metal passivator. The passivator prepared by the method has the advantages of good passivatingeffect and long passivating time, and has a promising application prospect.

The invention belongs to the technical field of macrolide antibiotic preparation, and particularly relates to non-irritating clarithromycin freeze-dried powder and a preparation method thereof. The clarithromycin freeze-dried powder injection is composed of a clarithromycin liposome and a freeze-drying protective agent, and 18-30 g of the freeze-drying protective agent is added into every 100 mL of a liposome solution; 100 mL of the liposome solution is prepared from the following raw materials: 2.0 g of clarithromycin, 1.8 to 2.2 g of cholesterol sodium sulfate, 6.0 to 6.4 g of lecithin, 0.5to 0.6 g of citric acid, 8 to 20 g of sucrose, 8 to 15 g of glucose and the balance of a phosphate buffer solution. According to the non-irritating clarithromycin freeze-dried powder disclosed by theinvention, the clarithromycin liposome is prepared by adopting the components of the cholesterol sodium sulfate, the lecithin, the citric acid and the clarithromycin, so that the particle size of theliposome can be reduced, the surface charge of the liposome can be increased, the liposome is stable, and the encapsulation efficiency of the liposome is high.

The invention relates to a long-acting compound anthelmintic liquid preparation as well as a preparation method and application thereof, and belongs to the field of veterinary drug preparations. The compound preparation is mainlycomposed of anti-parasitic active ingredients, namely milbemycin oxime, benzimidazoles and juvenile hormone ingredients, and comprises, in percent by mass, 0.5%-1% of milbemycin oxime, 5%-10% of benzimidazoles, 3%-5% of juvenile hormone, 0.1%-5% of macromolecule suspending agent, 0.1%-5% of wetting agent, 0.01%-1% of antioxidant and the balance of a dispersion medium.According to the invention, anti-parasitic drugs are combined for use, the insect-resistant spectrum is expanded, and a comprehensive and efficient in-vivo and in-vitro simultaneous-expelling effect is achieved.

The invention discloses a polluted drainage basin water and soil comprehensive treatment method, which comprises the following steps: planting suitable crop plants in red soil, absorbing iron components in the red soil through the crop plants, crushing the crop plants, mixing the crushed crop plants with sludge, granulating, and carrying out anaerobic pyrolysis at a suitable temperature to obtain bulk phase loaded zero-valent iron biochar and sludge biochar composite particles; a good effect is achieved on water and soil comprehensive treatment of the polluted drainage basin.

The invention relates to a contraceptive, in particular to an intelligent compound gestodene vaginal ring preparation with a memory effect. A vaginal ring consists of a controlled release membrane, a gestodene/ethinyloestradiol-containing carrier and a shape memory material, and can slowly release a contraceptive at constant speed within 21 days. By implementing the preparation, the remarkable contraception effect can be achieved, the inconvenience caused by the oral administration of the contraceptive is avoided, and the appliance of the administration is improved.

The invention relates to a dihydrocodeine tartrate sustained-release dropping pill for treatment of moderate pain and a preparation method thereof. The invention aims to solve the defects of an oral preparation, and provides the dihydrocodeine tartrate sustained-release dropping pill, which has advantages of high bioavailability, rapid effectiveness, long action time, low frequency of drug taking, convenient administration, little toxic or side effect, convenient storage and transportation, and suitability for oral administration, and the preparation method thereof.