54results about How to "Long-lasting protection" patented technology

Vaccines that target one or more antigens to a cell surface receptor improve the antigen-specific humoral and cellular immune response. Antigen(s) linked to a domain that binds to a cell surface receptor are internalized, carrying antigen(s) into an intracellular compartment where the antigen(s) are digested into peptides and loaded onto MHC molecules. T cells specific for the peptide antigens are activated, leading to an enhanced immune response. The vaccine may comprise antigen(s) linked to a domain that binds at least one receptor or a DNA plasmid encoding antigen(s) linked to a domain that binds at least one receptor. A preferred embodiment of the invention targets HIV-1 env antigen to the CD40 receptor, resulting in delivery of antigen to CD40 positive cells, and selective activation of the CD40 receptor on cells presenting HIV-1 env antigens to T cells.

A system and method for production of a printed product individualized for the customer, which offers the customer a selection of information content, depending on the variable payment (price) and the profile of interests thereof. Based on the price decision of the customer, a customer-specific relationship of optionally edited information content to customer-specific advertisement is generated. A dynamic matching of the profile of interests is carried out by feedback. The form of the printed product is determined by the selection of the information and the advertisements and the combination thereof according to the customer-specific relationship and profile of interests by means of an inventive layout. The printed product produced is suitable for traditional processing by print media, customer-specific in price, quality and quantity, achieves the interests of the advertisers with targeted advertising and the interests of the producers of the printed product with regard to achievable margins by providing a highly-attractive customer-specific product.

The invention discloses an aerogel waterproof and heat-insulating coating as well as a preparation method thereof. The coating with fireproof and heat-insulating properties is prepared by adding aerogel powder and ceramic powder which are subjected to hydrophilic modification as well as adding aids and fillers according to different formula proportions, and the coating is prepared by utilizing theproperty characteristic of a three-dimensional network structure of the aerogel, so that the defect that the existing coating is only fireproof and is not heat-insulating is solved and the coating has the heat-insulating characteristic. Meanwhile, nanometer ceramic powder is added in the coating, the nanometer ceramic powder in the coating is heated to be ceramic, one expanded ceramic film is formed on the surface of a base material, one air layer is arranged between the film and the base material, contact between flame and the surface of a vehicle metal material product is isolated, and heatis prevented from being transmitted to the surface of the metal by depending on the low heat-conducting coefficient characteristic of the aerogel in the coating. Through fireproof and heat-insulatingsynergistic effect, good barrier effect on heat and flame is guaranteed to be achieved no matter normal use of the metal part in the vehicle or occurrence of extreme fire accidents, and the fireproofproperty of the coating is enhanced.

The invention relates to a waterborne fluorine silicone resin modified acrylic acid concrete protective coating. The concrete protective coating comprises 10-20 parts of a fluorine emulsion, 20-40 parts of a silicone resin emulsion, 10-20 parts of a soap-free pure acrylic emulsion, 5-10 parts of sericit, 5-15 parts of talcum powder, 5-1 parts of ground calcium carbonate, 0.5-1.0 part of a dispersing agent, 0.05-0.2 part of a pHregulator, 0.3-0.5 part of a defoaming agent, 1.0-2.5 parts of propylene glycol, 0.5-2 parts of an antifungus and anti-mildew agent, 0.5-1.0 part of a thickening agent, 1.0-2.5 parts of a film-forming agent, 1.0-5.0 parts of a water repellent agent, 0.3-0.5 part of a flatting agent, 0.1-0.3 part of a tank bactericide and 30-45 parts of deionized water. The waterborne fluorine silicone resin modified acrylic acid concrete protective coating has the beneficial effects of weatherability, alkali resistance, washability, air permeability and mildew resistance. The concrete protective coating has a long-term protective effect for the concrete.

The invention proposes a novel foam forming machine and a foam forming method. The machine comprises a frame; the frame is provided with a feeding system, a mold mounting mechanism, a steam heating system, a cooling water system, a demolding mechanism and an electric automatic control system; the mold mounting mechanism includes a fixed template and a movable template; the movable template and the fixed template are arranged on the same one horizontal line; an oil cylinder drives the movable template to move left and right on the frame to form an opening/closing structure with the fixed template; the movable template and the fixed template are respectively communicated with the steam heating system and the cooling water system; and the demolding mechanism is behind the fixed template. The foam forming machine can adapt to molds with different sizes, and the movable template is connected with a composite material plate and a stainless steel plate layer, so that the equipment use performance at high temperature is improved; and the foam forming machine has the advantages of low mold investment, generality of semi-automatic and full-automatic mechanical molds, convenience to change the molds, high production flexibility and low manual dependence.

The invention discloses an application of tetrahydrobenzene difenoconazole to preparation of an agricultural fungicide or fungicide composition and a preparation method of the tetrahydrobenzene difenoconazole, and further discloses an application of a 4-((-(2-chlorine-4-(4-chlorophenoxy) phenyl)-4-methyl-1, 3-dioxolane-2-base) methyl)-4H-1, 2, 4-triazole (tetrahydrobenzene) compound to agricultural fungicide. The structural formula of the compound is as shown in the specification. According to the application, 35-40% of tailings serving as hazardous organic waste solids in the production process of agricultural fungicide difenoconazole are changed into useful pesticides, emission of the hazardous organic waste solids is greatly decreased, and environmental protection pressure of production enterprises is relieved. According to the preparation method, the yield of the difenoconazole can be increased, and cost is reduced.

The invention discloses a soil restoration agent with a heavy metal pollution treatment function and a fertilizing function and a preparation process of the soil restoration agent. The soil restoration agent is mainly prepared from the following raw materials in parts by weight: 260 to 310 parts of organic fertilizer, 25 to 31 parts of microbial agent, 0.03 to 0.07 part of difenoconazole, 0.05 to 0.1 part of pyrethrum, 0.03 to 0.09 part of rotenone, 0.04 to 0.08 part of chlorothalonil and 0.02 to 0.06 part of lactobacillus plantarum. The organic fertilizer is used as a main raw material, the microbial agent, insecticidal and sterilized vegetable drug and chemicals capable of alleviating the harm of soil heavy metal are added, so that not only can the fertilizer effect of the soil be improved, but also the soil restoration agent can enter the soil deeply to improve the heavy metal pollution and prevent the disease and insect pests.

The invention discloses a recombinant protein containing an SARS virus N antigen and a baculovirus displaying an N protein. The recombinant protein SP-N-TM is formed by connecting an N- end of the N protein of an SARS virus with a signal peptide SP of a baculovirus envelope protein GP64, and connecting a C- end with a transmembrane domain TM of the baculovirus envelope protein GP64. The recombinant baculovirus having the surface displaying the SARS antigen N protein is the recombinant baculovirus obtained by the steps of inserting a cording gene of the SP-N-TM into a donor plasmid, carrying out homologous recombination with a genome of a shuttle vector Bacmid through transposition to obtain a recombinant baculovirus genome, then transfecting a bombyx mori cell with the recombinant baculovirus genome, and packaging in the cell to obtain the recombinant baculovirus. The recombinant baculovirus allows an N protein gene of the SARS virus to be fused with a bombyx mori baculovirus envelope protein GP64 gene, realizes display of the N protein on the surface of a viral capsid, and has good immunogenicity and large application value.

The present invention relates to a microparticle. The microparticle includes one or more recombinant outer membrane vesicles, at least some of which display a fusion protein, where the fusion protein comprises at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides, and a polymeric coating over the one or more recombinant outer membrane vesicles. The present invention further relates to a method of eliciting an immune response in a mammal and a method of making encapsulated outer membrane vesicles displaying a fusion protein.

The invention discloses a method for preparing a modified polymethyl methacrylate anticorrosive coating on a magnesium alloy surface. The method comprises the steps of treating the magnesium alloy surface; mixing a tetraethyl orthosilicate solution with a gamma-methacryloxy propyl trimethoxyl silane solution, adding a catalyst, and heating to form sol; adding an ethanol solution in which zirconium oxychloride is dissolved into the sol, continuously heating, dropwise adding a sodium hydroxide alkaline solution, and controlling the reaction rate to form SiO2-ZrO2 hybrid sol; adding methyl methacrylate in which AIBN is dissolved, N-N-dimethylformamide and a cerous nitrate aqueous solution, and heating in the water bath environment to prepare modified PMMA-SiO2-ZrO2 hybrid sol; and smearing the PMMA-SiO2-ZrO2 hybrid sol on the surface of a magnesium alloy surface base material through rotation, drying, keeping the temperature, and cooling to prepare the modified polymethyl methacrylate anticorrosive coating on the magnesium alloy surface. According to the method, different catalysts and chemical additives are added, so that the corrosion resistance of a sol gel film on the magnesium alloy surface is improved.

The invention discloses a dryer with an oil removing and collecting energy-saving device, which comprises the oil removing and collecting energy-saving device. The oil removing and collecting energy-saving device comprises a box body. The box body is divided into two left and right independent spaces through a sealing diaphragm; the left part of the box body is used as a waste gas passage; the right part of the box body is used as a fresh air passage; a waste gas inlet is arranged in the box body and below the waste gas passage; a waste gas discharge outlet is arranged in the box body and above the waste gas passage; a filter screen, a lower oil removing and collecting device, a heat pipe and an upper oil removing and collecting device are sequentially arranged in the waste gas passage from bottom to top; the heat pipe passes through the sealing diaphragm to enter the fresh air passage; a fresh air inlet is arranged in the box body and above the fresh air passage; a fresh air outlet is arranged in the box body and below the fresh air passage; the heat pipe is arranged in the fresh air passage; the waste gas inlet of the oil removing and collecting energy-saving device is communicated with a waste gas port of the dryer; and the fresh air outlet of the oil removing and collecting energy-saving device is communicated with an air inlet of the dryer. Due to the adoption of the technical scheme, the adverse impact of oil substances in waste gas on a heat exchange surface is solved.

The invention belongs to the technical field of compound pesticides and particularly relates to antifungal composition comprising fenpyrazamine and difenoconazole. The fenpyrazamine and the difenoconazole are taken as the effective ingredients and account for 1%-80% by weight of the composition, and the weight ratio of the fenpyrazamine to the difenoconazole is 50:1-1:10. The composition can be prepared in one of the forms including an emulsifiable concentrate, wettable powder, a suspension, granules, a microemulsion, an emulsion in water and water dispersible granules. The antifungal composition is used for controlling crop diseases and has the characteristics of broad antifungal spectrum, high efficiency, low toxicity, low residues, obvious synergistic effect, reduction of use cost and the like.

The invention discloses a foamed glass insulation board for buildings, and a preparation method thereof. The foamed glass insulation board comprises an unfired foam glass insulation board base body, which comprises, by weight, 20-30 parts of glass powder; 20-45 parts of cement; 2-5 parts of a nanoscale inorganic porous material; 4-8 parts of polypropylene chopped fibers; 5-10 parts of a water-soluble polyester resin; 5-10 parts of water-soluble acrylic resin; and the balance of water, wherein the cement can be subjected to polymerization reaction with the glass powder, the nanoscale inorganicporous material is used as a foaming enhancer, and the water-soluble polyester resin and the water-soluble acrylic resin are subjected to cross-linking reaction in the foaming process of polymerization of the glass powder and the cement, so that the compactness and the mechanical strength of the baking-free foamed glass insulation board matrix are improved. According to the invention, on the premise of having excellent heat preservation and fireproof performance, the foamed glass insulation board is low in manufacturing cost and light in weight, high-temperature sintering is not needed in thepreparation process, energy consumption is greatly reduced, and the building material conforms to the technical development direction of energy conservation and low-carbon management of building materials.

A method for preventing contamination of a teat during administration of a sealant comprises the steps of introducing/delivering a sterilising agent into the teat and subsequently delivering the sealant into the teat. A sealant injector 1, has a nozzle 3, with a removable protective cap 2. A sterilising agent 4 such as a bacteriocin is provided between the nozzle 3 and the contents of the sealant injector 1.

The invention discloses an oil removal and collection apparatus with the function of energy saving. The apparatus is characterized in that: the apparatus comprises a casing, the casing is divided into two relatively independent spaces by a seal separator, the left space is an exhaust gas channel, and the right space is a fresh air channel; the casing is provided with an exhaust gas inlet at the lower side of the exhaust gas channel, the upper side of the exhaust gas channel is provided with an exhaust gas outlet, a filter screen, a lower oil removal and collection apparatus, heat tubes, and an upper oil removal and collection apparatus are successively arranged in the exhaust gas channel from the bottom to the top, and the heat tubes enter the fresh air channel through traversing the sealseparator; and the casing is provided with a fresh air inlet at the upper side of the fresh air channel, the lower side of the fresh air channel is provided with a fresh air outlet, and the heat tubes are arranged in the fresh air channel. Above technical scheme allows the negative influence of oily substances in the exhaust gas to heat exchange surfaces to be solved.

The invention discloses a soil remediation agent with the heavy metal pollution treatment and fertilization effects and a preparation method thereof.The soil remediation agent is mainly prepared from, by mass, 260-310 parts of organic fertilizer, 25-31 parts of a microbial agent, 0.03-0.07 part of difenoconazole, 0.05-0.1 part of pyrethrum, 0.03-0.09 part of derris, 0.04-0.08 part of chlorothalonil and 0.02-0.06 part of lactobacillus plantarum.According to the soil remediation agent, the organic fertilizer serves as a main raw material, the microbial agent capable of reducing heavy metal in soil and the plant pesticides and chemicals capable of killing pests and bacteria are added, and thus the soil remediation agent can improve the fertilizer effect of soil and can also penetrate deep into soil to relieve heavy metal pollution and prevent and treat pest and disease damage.

Vaccines that target one or more antigens to a cell surface receptor improve the antigen-specific humoral and cellular immune response. Antigen(s) linked to a domain that binds to a cell surface receptor are internalized, carrying antigen(s) into an intracellular compartment where the antigen(s) are digested into peptides and loaded onto MHC molecules. T cells specific for the peptide antigens are activated, leading to an enhanced immune response. The vaccine may comprise antigen(s) linked to a domain that binds at least one receptor or a DNA plasmid encoding antigen(s) linked to a domain that binds at least one receptor. A preferred embodiment of the invention targets HIV-1 env antigen to the CD40 receptor, resulting in delivery of antigen to CD40 positive cells, and selective activation of the CD40 receptor on cells presenting HIV-1 env antigens to T cells.

The invention belongs to the technical field of negative oxygen ion exterior wall coating and provides waterborne forest negative oxygen ion exterior wall coating and a preparation method thereof in order to solve the technical problem that the existing exterior wall coating cannot sustainably release negative oxygen ions. The exterior wall coating comprises the following raw materials in parts byweight: 0.1-0.3 part of hydroxyethyl cellulose, 0.1-0.3 parts of a pH regulator, 0.5-1.0 part of a dispersing agent, 15.0-20.0 parts of titanium dioxide, 5.0-10.0 parts of ultrafine ground calcium carbonate, 3.0-5.0 parts of a water repellent agent, 1.0-2.0 parts of a negative oxygen ion additive, 0.2-1.0 part of a mildew preventive, 0.5-1.0 part of a preservative, 35-45.0 parts of pure acrylic emulsion, 0.3-0.5 parts of an associated thickening agent, 1.0-2.0 parts of a film forming additive, 1.5-3.0 parts of a defoaming agent and 13.0-25.0 parts of deionized water. The preparation method comprises the following steps: preparation of hydroxyethyl cellulose liquid, preparation of defoaming liquid, preparation of negative oxygen ion mixed solution and exterior wall coating. The exterior wall coating provided by the invention has the characteristics of sustainably releasing negative oxygen ions and removing peculiar smell of the coating.

The invention discloses a steamed non-fired foamed ceramic insulation board for a building. The steamed non-fired foamed ceramic insulation board comprises a non-fired foamed ceramic insulation boardmatrix formed by adopting a foaming process. The non-fired foamed ceramic insulation board matrix comprises the following raw materials in parts by weight: 10-25 parts of ceramic powder, 35 to 55 parts of cement, 2-5 parts of a nanoscale inorganic porous material, 4-8 parts of polypropylene chopped fibers, 5 to 10 parts of water-soluble polyester resin and 5 to 10 parts of water-soluble acrylic resin, with the balance being water. According to the invention, the cement can undergo a polymerization reaction with the ceramic powder, and the water-soluble polyester resin and the water-soluble acrylic resin undergo a cross-linking reaction in the foaming process of polymerization of the ceramic powder and the cement, so the compactness and the mechanical strength of the non-fired foamed ceramic insulation board substrate are improved; on the premise of having excellent heat preservation and fireproof performance, the board is low in manufacturing cost and light in weight; and meanwhile, high-temperature sintering is not needed in the preparation process of the board, so energy consumption is greatly reduced, and the board conforms to the technical development direction of energy conservation and low-carbon management of building materials.