The invention discloses a method for wastewater zero discharging of the leather industry. The method is characterized by comprising the following steps of 1, cow leather preprocessing, 2, softening processing, 3, oxidation aeration processing, 4, sedimentation, and 5, filtering and oil removal. According to the softening processing in the leather manufacturing process, fur is prevented from being degraded by a chemical reducing agent, and COD and BOD loads in a depilation waste liquid are reduced. According to the oxidation aeration processing, the load impact resistance is large; the physical technology is utilized for reducing the dosage of harmful chemical substances and lowering the suspended matter content in wastewater, a solid-liquid separator is used for solid-liquid separation, and the amount of metal ions is decreased; according to the step of filtering and oil removal, oil components are removed, the processing efficiency is high, it is ensured that water flows out stably, the water quality is reliable, resources are saved, and the environment is protected.