50 results about "O-Anisidine" patented technology

Provided is an electrochemical synthetic method of ortho-anisidine, which includes four steps that firstly the method needs to be accomplished in an two-chamber electrolysis bath which is separated by employing a cation-exchange membrane, a copper sheet is taken as a negative electrode, a ruthenium net is taken as a positive electrode, a saturated calomel electrode is taken as a reference electrode, the negative electrode and the reference electrode are installed inside a cathode chamber of the electrolysis bath, and the positive electrode is installed inside an anode chamber of the electrolysis bath. Secondly methanol is taken as solvent, sulphuric acid is taken as supporting electrolyte, ortho-nitroanisole is taken as electrolytic reaction substrate, the solvent and solution of the supporting electrolyte are injected into the cathode chamber and the anode chamber, and the electrolytic reaction substrate is injected into the cathode chamber. Thirdly the electrolyzation is performed under the condition of normal temperature and pressure and the condition that the negative electrode is added with a certain constant voltage relative to the reference electrode, the voltage value of the constant voltage is between -0.6 to -1.0V. Fourthly after the electrolyzation is finished, the electrolyte is post-processed to prepare the product of the ortho-anisidine with the production ratio between 19.1-53.4%. The method has the advantages of simple requirement, mild reaction conditions, easy preparation of the electrodes, low price, small pollution in the process of reaction and the like, which is a greening production line.

The invention discloses a production process for o-aminoanisole. The production process for the o-aminoanisole comprises the following steps: carrying out etherification by using methanol and sodium hydroxide as methoxyl reagents to obtain o-nitroanisole; and reducing the o-nitroanisole by sodium sulphide under the effect of a catalyst to synthesize the o-aminoanisole. According to specific reaction, main reaction is as shown in specification. In the production process for the o-aminoanisole, production raw materials are easily obtained; the production process is simple and easy; the problemsof difficulty in recycling of the catalyst and serious fire in hydrogenation reduction are solved, a certain amount of waste water is generated by reduction through sodium sulfide, and the productionprocess for the o-aminoanisole has the advantages of good product quality and high safety factors.

The invention discloses a method for determining six aromatic amine compounds in cigarette mainstream smoke by using online SPE / LC-MS / MS. It uses the Cambridge filter and an absorption bottle containing 2% formic acid solution to capture the aromatic amine compounds in the main cigarette smoke particle and gas phase matters, respectively, ultrasonically extracting the filter by 2% formic acid solution, adding interior labels into the two solutions and determining the six aromatic amine compounds by online SPE / LC-MS / MS, including o-toluidine, 2,6-dimethylaniline, o-anisidine, 1-aminonaphthalene, 2-aminonaphthalene and 4-aminobiphenyl. The method has the advantages of simplifying the sample pretreatment process and extracting with the formic acid solution to reduce the pollution. The two-dimensional in-line solid-phase extraction composed of the cationic column and the reversed-phase C18 column is used to purify the sample to be tested and the purification effect is good; each target is quantitatively analyzed using their specific internal standard, effectively reducing the matrix effect.

The invention provides a production method of oamino pheylmethyl ether, and the method comprises the following steps of: reacting ortho nitrochlorobenzene serving as a raw material with sodium methoxide for carrying out a methoxylation reaction to obtain orthonitroanisole; secondly, carrying out hydrogenation reduction on the orthonitroanisole by using methanol as a solvent in the presence of a catalyst to prepare the oamino pheylmethyl ether; and finally, carrying out dealcoholization, dehydrogenation and refining on reactants to obtain the oamino pheylmethyl ether as a finished product. The production process comprises the following steps of: preparing sodium methoxide, etherifying the ortho nitrochlorobenzene, distilling the methanol and nitroether for separation, hydrogenating the orthonitroanisole, distilling a hydrogenating solution for separating the oamino pheylmethyl ether and treating wastewater. The production method has the characteristics of simple process, short procedure, continuity in reaction, high production efficiency, good product quality, less energy consumption, concentrated purification of reaction wastewater and no emission, and is suitable for producing the oamino pheylmethyl ether by using the ortho nitrochlorobenzene as the raw material.

The invention relates to a preparation method of red base B. In the presence of an acylation reaction solvent, o-aminoanisole and formic acid are subjected to formylation reaction at 80-102°C, and o-formamide is obtained by filtration after the reaction Anisole: o-formamide anisole is added to the sulfuric acid solution, and when the temperature of the reaction system is controlled at 0-70°C, nitric acid is added to the reaction system for nitration reaction, and after the reaction is completed, it is obtained by filtration 2-methoxy-4-nitroformanilide; 2-methoxy-4-nitroformanilide is hydrolyzed at 80~120°C in the presence of sulfuric acid and water. After the reaction, Separation, adjusting the pH to 6-7 with soda ash, and then filtering to obtain the red base B. The product of the invention has high yield, low cost, good quality and few by-products, greatly reduces the waste water produced in the production process of the red base B, meets the requirements of clean production, is easy to operate, and is convenient for industrialization.

The invention discloses a method for preparing o-anisidine by catalytic hydrogenation. The method comprises the following steps of: mixing o-nitroanisole, methanol and a catalyst Raney-Ni, adding the mixture into a pressure kettle, performing replacement by hydrogen, introducing the hydrogen to maintain the pressure of between 0.5 and 2MPa, heating to the temperature of between 40 and 80 DEG C, introducing the hydrogen continuously for 3 to 10 hours, recovering the methanol, separating liquid and rectifying to obtain the o-anisidine. The method has the advantages of environment friendliness, low energy consumption, high yield and high quality of products.

A preparation method of the bacterial drug-resistant inhibitor is provided, which is that the Beta-naphthamine is utilized as raw material and reacts with the urea to gain the N-(2-naphthol)- thiourea, and then reacts with the o-amino pheylmethyl ether to gain INF271, namely, 1-(2- methoxyphenyl)-3-naphthyl-2-thiourea. (1) The Beta-naphthamine and urea are added in water and are added with the diluted acid for 1h to 5h heating and reflux and are filtered after cooling to gain 1-(naphthol-2base)-thiourea; (2) 1-(naphthol-2base)-thiourea and the o-amino pheylmethyl ether mix with the diluted acid and are heated to 100 DEG C. to 108 DEG C., and then react for 1h to 5h to gain the 1-(2- methoxyphenyl)-3-naphthyl-2-thiourea after cooling and filtering. The diluted acid applied in the reaction can be sulphuric acid, hydrochloric acid and acetic acid, etc. the priority is hydrochloric acid.

The invention discloses a quick drying type color fixing agent. The quick drying type color fixing agent is prepared from the following components in percentage by weight: 15-25 parts of 2,5-diclorobenzic acid, 10-20 parts of sorbic acid, 8-13 parts of pinacolonelidinone, 18-26 parts of o-aminoanisole, 8-15 parts of 4,2-dinitroanisole, 6-12 parts of 2-amino-3,4-dyhydroxy diphenyl ketone, 7-13 parts of triethylene tetramine, 3-15 parts of alpha-alpha-diethoxybenzophenone, 10-18 parts of cyclohexanol and 50-80 parts of distilled water. By virtue of the color fixing agent, total time of a fabric color fixing process can be shortened, the color fixing efficiency is improved and the color fixing effect is good.

The invention discloses a preparation method of environment-friendly CI disperse orange 29, which belongs to the technical field of disperse dyes. The preparation method comprises: stirring and dispersing the dye filter cake of untreated CI disperse orange 29 in water into a slurry; At ‑100°C, use sodium hydroxide and / or sodium carbonate to adjust the pH to greater than 9, and then use sulfuric acid and / or hydrochloric acid to adjust the pH to 7‑9; then filter and separate, and wash the filter cake with water until the pH is neutral; the separated environmental protection Type CI Disperse Orange 29 filter cake, through sanding, coloring, drying commercial processing of disperse dyes, the finished dye product of CI Disperse Orange 29 which is environmentally friendly can be obtained. The method of the present invention is simple and economical, and can limit the detectable anthranilic ether in the dye product of CI Disperse Orange 29 to below 150ppm, which meets the national standard; thus the dyed textile meets the EU standard.

The invention relates to a method for preparing m-chloroaniline by using meta-position oil, which belongs to the technical field of preparing m-chloroaniline, and specifically includes the steps of batching reaction, water washing, drying, three-stage vacuum distillation, crystallization, reduction, redistillation and the like. The present invention uses waste meta-oil produced by p- and o-nitrogen and industrial waste liquid sodium hydrosulfide as raw materials, utilizes methoxylation, crystallization and reduction to prepare m-chloroaniline, and generates by-products o-aminoanisole and p- Anisole, thereby realizing low cost, high output, compared with existing production technology, has obvious cost advantage, has higher economic benefit.