44results about How to "Avoid performance differences" patented technology

The present invention provides a tamsulosin hydrochloride sustained-release capsule. The tamsulosin hydrochloride sustained-release capsule of the present invention can avoid the sudden release of the drug tablets and the performance differences generated from the gastric emptying differences, display minor food effect or do not display food effect, and obtain the stable curve of the plasma drug concentration and longer action time simultaneously, so as to reduce the occurrence of cardiovascular side effects, greatly improve the safety, effectiveness and compliance of the medication for the patients. The tamsulosin hydrochloride sustained-release capsule of the present invention can ensure the sustained and regular release of the main ingredient tamsulosin hydrochloride after the oral administration, and the present invention is characterized by convenient administration, durable function, stable efficacy, fewer side effects and so on.

The invention discloses a hollow-out unit body suitable for the metal 3D printing technology. The hollow-out unit body comprises a main structure and an extension structure. The main structure comprises a dodecahedron structure formed by main rib strips serving as the edges. The extension structure comprises extension rib strips extending outwards from the directions of the body diagonals of a dodecahedron. The included angle between each main rib strip and the projection plane is theta, and theta is larger than or equal to 30 degrees but smaller than or equal to 90 degrees. The invention further discloses a metal part comprising the hollow-out unit body. The hollow-out unit body is of a self-supporting structure and suitable for metal 3D printing forming process conditions. Weight reduction of the unit body structure exceeds 90% maximally. A hollow-out weight reduction structure formed by the unit bodies through size changing, direction changing, density changing and other array modes is good in isotropy and high in weight reduction ratio, and the reliability of the part is improved.

The present invention provides a method for preparing an ion-imprinted polymer based on functional monomers of ribonucleotides, which is characterized by comprising: dissolving inorganic salts of template ions in double distilled water, then adding ribonucleotides, at 450-550 rpm Stir for 1~2h, add aminophenylboronic acid to the above solution, use 50-100mmol / L sodium hydroxide to adjust the pH of the solution to 8-10, pass nitrogen and deoxygenate, add nano-silica and 0.05~0.2mol / L permeate. Ammonium sulfate solution, nitrogen blowing for 20-40min, continuous magnetic stirring reaction for 10-14h, after the reaction is over, centrifuge to collect the product, use 50-100mmol / L sulfhydryl-containing compound to elute the template ion, then use double distilled water to wash, centrifuge The product was collected and dried at 60-80°C to obtain an ion-imprinted polymer based on ribonucleotide functional monomer. In the preparation process of the present invention, ribonucleotides with good affinity for metal ions are selected as functional monomers, and the selectivity of ion imprinting can be further improved through the synergistic effect of the imprinting monomer and the imprinting cavity.

The invention provides a large-diameter thick walled pipe postweld heat treatment method. By adopting the large-diameter thick walled pipe postweld heat treatment method provided by the invention, insulating temperature is determined according to a hardness range of a base material in the postweld heat treatment process, simultaneous heating of an inner wall and an outer wall is adopted, a heatingwidth is determined according to a formula, a power of a heater is determined according to a formula, and thus the heat treatment quality of a weld crater is effectively ensured, a temperature difference between the inner wall and the outer wall of the weld crater in postweld heat treatment is lowered to meet the standard requirement or a higher standard to avoid the phenomenon of base material overburning or difference between the weld crater properties of the inner wall and the outer wall caused by a temperature deviation, weld crater heat treatment can be ensured to mold at a time at the same time to avoid the phenomenon of heat treatment again, the heat treatment effect is improved, and the economic benefit is very considerable.

The invention discloses a method for manufacturing a high-strength, toughness and layered tear-resistant steel plate with a thickness of 50-80 mm. The continuous casting slab with the same composition as the steel plate is heated to 1210-1250° C., and the heating time is controlled at 1.1-1.2 min / mm. The casting slab temperature is ≥1150°C, the starting rolling temperature in the recrystallization zone is ≥1050°C, rolling 6-7 passes, the intermediate slab is waiting for temperature, the starting rolling temperature in the non-recrystallization zone is controlled at 800-830°C, and the final rolling temperature is controlled at 800~830℃, rolling 8~9 passes, after rolling, the steel plate is cooled by laminar flow in the strong cooling zone and the intermediate cooling zone at the cooling rate of 6.5~13℃ / S and 2.0~6.0℃ / S respectively, ACC system The roll speed is 0.6~0.8m / s, and the grain size of the steel plate produced is 10.5~12 grades; the comprehensive properties of the steel plate are: yield strength ≥ 420MPa, ‑40°C longitudinal impact energy ≥ 200J, Z-direction performance sectional reduction rate ≥ 65%. The present invention obtains high-strength steel plates by precisely controlling rolling, and then reasonably opens the water groups in the strong cooling zone and the intermediate cooling zone to control the cooling rate, effectively refine the grain and structure of the steel, and reduce core defects.

The invention belongs to the technical field of steel materials, and discloses a production method of a high-quality thick steel plate. The production method comprises the steps that the procedure ofhigh-temperature rolling and the procedure of low-temperature rolling are conducted in a non-recrystallization area in the rolling process, wherein the procedure of high-temperature rolling comprise afirst finish rolling stage, and in the first finish rolling state, a low-speed high-pressure rolling process is adopted, the initial rolling temperature is 900-930 DEG C, a required cumulative rolling rate is equal to or greater than 15%, and the maximum single-pass rolling rate is equal to or greater than 12%; the procedure of low-temperature rolling comprises a second finish rolling stage, andin the second finish rolling stage, a low-temperature high-pressure rolling process is adopted, the initial rolling temperature of a steel plate is 780-820 DEG C, and the finish rolling temperature is760-780 DEG C; and steel is discharged after being rolled and then rapidly enters water to be cooled. By adoption of the production method of the high-quality thick steel plate, the performance of the high-strength and high-tenacity thick steel plate produced through a continuously cast plate is improved, and meanwhile, the technical problems of slow rolling rhythm and low efficiency are solved.

The invention provides a real-time neurofeedback device, system, method and computer storage medium, and relates to the technical field of neurofeedback. The real-time neurofeedback device includes an acquisition module, a decoding module, an encoding module, and a feedback modulation module. After the acquisition module, the decoding module, an encoding module, and the feedback modulation module are electrically connected in sequence, the feedback modulation module is connected to the acquisition module. The modules are connected to form a closed-loop, dynamic real-time neurofeedback device. The present invention solves the problems existing in the applicability, effectiveness and accuracy of the existing neurofeedback technology, realizes self-adaptive, dynamic and precise control of the amplitude and phase of the specific EEG rhythm, and avoids the Differences in effect due to factors such as experience.

The invention discloses a laminar flow cooling U type control method used for hot rolling strip steel. According to the method, strip steel is cooled in five sections, wherein the first section is the head part with cooling length of HL1, the cooling temperature of the first section is cooling temperature T1 of the head part; the second section is a head part buffering region with cooling length of HL2, the cooling temperature of the second section is cooling temperature T2 of the head part buffering region; the third section is the middle part with cooling length of ML, the cooling temperature of the third section is coiling temperature CT; the fourth section is a tail buffering region with cooling length of TT1, the cooling temperature of the fourth section is the cooling temperature T3 of the tail buffering region; and the fifth section is a tail part with cooling length of TT2, and the cooling temperature of the fifth section is the cooling temperature T4 of the tail part. The invention also discloses a laminar flow cooling U type control system used for the hot rolling strip steel. The control method and system can effectively eliminate performance differences between the head and tail parts and the middle part of the strip steel.