This utility model discloses a chemical safety sampling device, including a sampling tube installed on the side of a tank and a protective box covering the sampling tube. A solenoid valve is installed on the sampling tube, and the protective box has a door. One side of the door is hinged to the protective box, and the other side of the door is connected to the protective box via an electromagnetic lock. A start switch is installed on the surface of the protective box. The start switch, electromagnetic lock, and solenoid valve are all connected to a PLC controller. This utility model, by setting a protective box outside the sampling tube and placing the sampling container inside the protective box for sampling, can effectively avoid safety accidents caused by splashing chemical cleaning solutions.