The invention provides a pressure sensing device with high sensitivity, which comprises a wideband light source, a circulator, a sensing head and a spectrum analyzer, wherein the sensing head is composed of a corrosion multimode fiber and an ultraviolet adhesive. The pressure sensing device with high sensitivity is characterized in that after the multimode fiber end surface is corroded, a conical cavity is obtained, the ultraviolet adhesive is penetrated in the conical cavity, and an air cavity coated by the ultraviolet adhesive is formed in the conical cavity. The circulator receives light from the wideband light source and transmits the light to the sensing head, the sensing head reflects the light back to the circulator, the light is then transmitted to the spectrum analyzer via the circulator, a similar Fabry-Perot interferometer is formed, and wavelength drift of a reflection spectrum characteristic peak is measured, and thus, the numerical value of a tested environmental parameter can be calculated. The pressure sensing device with high sensitivity is applicable to measurement on various environmental parameters, particularly, pressure measurement, and has the advantages of compact structure, simple manufacturing, high sensitivity, wide measurement range, and low cross sensitivity.