The invention discloses a device for 
coupling acetone-butyl 
alcohol fermentation and separation. The device consists of a 
fermentation tank, an extraction 
tower, a heater and a condenser, wherein the extraction 
tower is arranged at the upper part of the 
fermentation tank and is communicated with the fermentation tank; the heater is arranged at the upper part of the extraction 
tower; and the condenser is communicated with the top part of the extraction tower. 
Acetone-butyl 
alcohol fermentation liquor in a conventional fermentation tank is added into the fermentation tank of the 
coupling device or is directly used for performing 
acetone-butyl 
alcohol fermentation in the fermentation tank of the 
coupling device; an extracting agent with a high 
boiling point is filled in the extraction tower; the 
acetone, the butyl alcohol and the 
ethanol generated through the fermentation are extracted into the extracting agent, and move upwards under the driving of the concentration difference and 
density difference between the generated acetone, butyl alcohol and 
ethanol and the extracting agent; and the heater is used for heating the extracting agent at the inner upper part of the extraction tower so that the acetone, the butyl alcohol and the 
ethanol dissolved in the extracting agent are distilled out continuously. According to the method provided by the invention, not only can the 
product inhibition of the acetone-butyl alcohol fermentation be effectively eliminated, the product yield and the 
raw material utilization ratio of the acetone-butyl alcohol fermentation be improved, but also the production 
energy consumption and cost can be effectively reduced.