33 results about "Acetohydroxamic acid" patented technology

This invention discloses a sustained-release nitrogen fertilizer containing secondary and trace elements. The sustained-release nitrogen fertilizer is composed of: urea 10-96 parts, ammonium sulfate 0.1-78.8 parts, attapulgite powder 0-8 parts, ammonium chloride 0.1-78.8 parts, magnesium sulfate 0.05-2.0 parts, borax 0.01-1 part, copper sulfate 0.01-0.2 part, manganese sulfate 0.01-0.6 part, ferrous sulfate 0.01-1 part, zinc sulfate 0.01-1 part, acetohydroxamic acid 0.01-0.02 part, composite amino acids 0.01-1 part, and dicyandiamide 0.01-0.2 part. The sustained-release nitrogen fertilizer is prepared by: mixing the above components, adding into a disc granulator, spraying an appropriate amount of water, granulating and drying. The sustained-release nitrogen fertilizer has such advantages as long effective period and high effective utilization rate (above 45%). Crops applied with the sustained-release nitrogen fertilizer have such advantages as high stress resistance and high yield.

During the preparation of acetohydroxamic acid, hydroxylamine chloride and methyl acetate are first mixed in a reactor, and solid alkali catalyst to neutralize hydrochloric acid carried by hdyroxylamine chloride and alcohol in the same volume as methyl acetate as solvent are then added, so that a synthetic reaction is effected to produce acetohydroxamic acid. The artificially prepared acetohydroxamic acid has a purity has high as 80% and may be re-compounded into 5% product suitable for use as feed additive. The product may find its wide use in stockbreeding, agriculture, medicine and environment protection.

The invention relates to a compound deodorant for livestock and poultry houses, and belongs to the technical field of livestock and poultry breeding management. An adopted technical scheme of the compound deodorant for the livestock and poultry houses comprises the following ingredients in mass percentage: 60-73% of acetohydroxamic acid, 2-8% of microbial bacterium dry-powder, 20-32% of tea residues and 4-10% of mineral powder. The compound deodorant for the livestock and poultry houses has the following beneficial effects: (1), the compound deodorant provided by the invention is simple, scientific and rational in formula, and has multiple coordination functions of regulating internal environment of digestive tracts of the livestock and the poultry, improving feed utilization rate as well as enhancing immunity of the livestock and the poultry; and the compound deodorant solves odor pollution problems of the farms in a highly effective way; and (2), the compound deodorant is simple in preparation method, low in cost and convenient to use; thus, economic benefits of the breeding industry are improved by the compound deodorant.

The invention discloses a fattening pig feed additive prepared from the following raw materials in parts by weight: 10-20 parts of astragalus polysaccharide; 5-10 parts of fucoidan; 3-6 parts of tea saponin; 1-3 parts of acetohydroxamic acid; 3-6 parts of tangerine peel; 5-10 parts of chamomile; 6-12 parts of fried atractylodes; 0.1-0.5 parts of beta-complex detoxifying enzyme; and 3-5 parts of 5-nitroguaiacol sodium salt. The fattening pig feed additive has the effects of strengthening spleen and appetizing, expelling evil spirits and solidifying roots, the ratio is reasonable, the cost is low, the effect is good, and the weight increase effect is significant, the feed addictive improves the production performance, increases economic benefits, and can also improve the body's immunity.

The invention relates to a feed additive for producing selenium-rich beef. The feed additive is characterized by being prepared from the following substances in parts by weight: 15-25 parts of 30% enveloped mercaptamine, 8-12 parts of dihydropyridine, 130-150 parts of cardamine violifolia, 110-130 parts of honeysuckle, 90-110 parts of roots of Chinese pulsatilla, 70-90 parts of medicated leaven, 70-90 parts of malt, 70-90 parts of semen raphanin, 70-90 parts of fructus aurantii, 70-90 parts of fructus quisqualis, 30-50 parts of acetohydroxamic acid, 50-60 parts of commercially available selenium yeast which contains 2000mg/kg of selenium, 50-60 parts of commercially available bacillus subtillis and 50-70 parts of medical stones. The feed additive for producing selenium-rich beef has the advantages of preventing various diseases of cattle, providing safe, nutritious and healthy food for the citizens, being the best food and way for selenium supplementation of the citizens, and having important practical significance.

The invention relates to a preparation method of a special biological selenium-rich nutrition solution for plants, wherein the components of the formula comprises (by weight): 0.3-1.3% of cystine, 0.5-1.5% of a methionine-copper complex, 0.7-1.7% of Clostridium butyricum, 1-2% of a common yam rhizome extract, 1.2-2.1% of an amino acid-iron complex, 1.3-2.2% of a Sterculia lychnophora Hance extraction liquid, 1.9-2.9% of folic acid, 2.5-3.5% of Saccharomyces cerevisiae, 2.9-3.9% of a Fritillaria ussuriensis Maxim extract, 2.3-3.3% of acetohydroxamic acid, 2.7-3.7% of sorbitol, 2.8-3.8% of a fructus momordicae extract, 1.1-2.1% of Bifidobacterium bifidum, 0.5-1.5% of Trisodium hydrogen diphosphate, 0.1-1% of Glycerol, 0.8-1.8% of a Cassia nomame extract, 0.2-1% of Avocado oil, 0.9-1.9% of Macrocystis pyrifera powder, 2.7-3.7% of probiotics, 1.7-2.7% of yeast selenium, and 71.9-52.4% of water. According to the present invention, the special biological selenium-rich nutrition solution canwell supplement nutrition elements required in plant growth, strengthening and enlarge seedlings, promote the robust growth of plants, enhance the stress resistance, the cold resistance and the disease resistance of plants, achieve the strong stems and the green leaves of plants, fundamentally reduce the occurrence of diseases, balance the plant nutrition, ensure the healthy growth of plants, andprolong the flowering period of plants.

The invention provides a buffalo calf lick brick and a preparation method thereof, and belongs to the field of feeds. The buffalo calf lick brick is prepared from the following raw materials in partsby weight: 200 to 400 parts of hydroxymethyl cellulose, 250 to 450 parts of bentonite, 2800 to 3200 parts of feed salt, 400 to 500 parts of urea, 100 to 130 parts of anhydrous calcium hydrophosphate,120 to 150 parts of mineral additives, 400 to 600 parts of composite vitamins, 0.2 to 1 part of acetohydroxamic acid, 1 to 3 parts of lactoferrin, 1 to 5 parts of rumen bypass protein, 1 to 5 parts ofalgal polysaccharide, 1 to 5 parts of yeast cell wall polysaccharide and 20 to 50 parts of plant extracts. The buffalo calf lick block is rich in nutrition and capable of maintaining electrolyte balance of calf bodies, preventing and treating mineral nutrient deficiency, promoting growth, improving feed conversion, improving resistance and preventing and treating ticks.

The invention relates to a medicinal health agent for preventing and treating canine/feline magnesium ammonium phosphate stones, which is characterized in that the agent is prepared by evenly mixing the following effective components in ratio by weight or unit: 100 to 500 mg of acetohydroxamic acid, 1,000 to 4,000 mg of methenamine and 4,000 IU of vitamin A. The medicinal health agent for preventing and treating canine/feline magnesium ammonium phosphate stones is added as a unit for each kilogram of canine/feline feed. The agent utilizes the characteristic of inhibiting urease activity through acetohydroxamic acid to reduce the ammonia concentration and pH of urine and prevent the formation of infectious urinary stones or inhibit the growth thereof, utilizes the methenamine to kill pathogens and maintain urine acidity so as to destroy the conditions of crystal formation, and utilizes the vitamin A to maintain the integrity of urinary-tract epithelium so as to realize the activity of crystallization inhibitors and inhibit crystallization. The agent is reasonable in compatibility, jointly uses medicaments from different angles to eliminate the inducing factors of stones, and plays adefinite role in preventing magnesium ammonium phosphate stones after the agent is added to canine/feline diets. The agent has the advantages of simple preparation, remarkable effects and wide application range.

The invention relates to a synthetic method for acetohydroxamic acid. The method synthesizes the acetohydroxamic acid with hydroxylamine sulfate and ethyl acetate as raw materials and with an ethanol solution of sodium ethoxide as a catalyst. Compared with a traditional synthetic method (e.g., using sodium hydroxide as the catalyst), the synthetic method provided by the invention has the advantages of simple and convenient process, easily-available raw materials which are bulk chemical materials, low cost, high yield and facilitation to industrial popularization.

The invention discloses a naproxen copper complex with a function of inhibiting the urease activity and a preparing method thereof, and belongs to the technical field of complex synthesis and medicinal chemistry. According to the naproxen copper complex, naproxen and 1,3-propane diamine serve as ligands, a copper ion serves as a center ion, and through a solvent evaporation method, a mononuclear-structure naproxen copper complex is prepared. The naproxen copper complex has the good biological activity, it discovers after detection that IC50 values of the naproxen copper complex and positive control medicine acetohydroxamic acid (N-glycolamide) are 1.69 micromole/L and 6.26 micromole/L respectively with respect to urease inhibition, it indicates that an effect of the complex for inhibitingthe urease activity is better than an effect of acetohydroxamic acid, the inhibition ratio of the complex for the urease activity is 72.6%, and the naproxen copper complex is a good urease inhibitor.

The invention relates to a preparation capable of reducing concentration of ammonia gas in a livestock housing and a preparing method of the preparation. The preparation comprises components in percentage by weight as follows: 3%-10% of yucca schidigera extracts, 2%-10% of acetohydroxamic acid, 1%-5% of isobutyric acid, 1%-5% of origanum oil, 5%-15% of calcium superphosphate and the balance of montmorillonite. The preparation is scientific in formula, efficient, safe, environment-friendly, low in cost and simple to prepare. The preparation reduces ammonia gas by restraining and killing putrefying bacteria and restraining urease activity and can absorb ammonia gas in the livestock housing. The concentration of ammonia gas in the livestock housing can be greatly reduced by using the preparation.

The present invention belongs to the technical field of feeds and particularly relates to a low defecation nitrogen environment protection type special feed for fattening pigs. The special feed comprises a Bangji S-AALN functional package and the Bangji S-AALN functional package comprises the following components of threonine, methionine, tryptophan, valine, insoluble fibers, acetohydroxamic acid,modified zeolite and tributyrin. The feed comprises the following ingredients of corns, bran, rice bran meal, corn germ meal, soybean oil, 70% lysine, high temperature resistant phytase, compound vitamins, compound trace elements, the Bangji S-AALN functional package, etc. By using a combination of the amino acids to replace a part of common protein raw materials, the feed provides micropowder type insoluble fibers not damaging intestinal tracts, reduces concentrations of toxic amines and nitrogen in feces in the intestinal tracts, improves an intestinal health condition of the pigs in the fattening period and is reasonable in nutrition. Each of the ingredients has a joint function. The environment protection type special feed balances supply and demand of the amino acids, reduces the toxic amines and is low in defecation nitrogen in the fattening period, reduces a feed-to-meat ratio of the pigs and improves economic efficiencies.

This invention provides that Ropinirole (4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one) possess potent urease inhibitory potential (in vitro) with 97.3% inhibition and IC₅₀=11.7+0.46 μM, when compared to the standard inhibitors i.e. acetohydroxamic acid (IC₅₀=41.5+1.50 μM), and thiourea (IC₅₀=21.0+0.50 μM).

The invention relates to a feed additive for producing selenium-rich beef. The feed additive is characterized by being prepared by mixing the following substances in parts by weight: 15-25 parts of 30% coated cysteamine hydrochloride, 8-12 parts of dihydropyridine, 130-150 parts of cardamine violifolia, 110-130 parts of flos lonicerae, 90-110 parts of stevia rebaudiana, 70-90 parts of rhizoma gynurae, 70-90 parts of fructus hordei germinatus, 7-9 parts of laifeng crossostephium leaf extract, 70-90 parts of fructus aurantii, 70-90 parts of fructus quisqualis, 30-50 parts of acetohydroxamic acid, 50-60 parts of commercially available selenium yeast containing 2,000mg/kg of selenium, 50-60 parts of commercially available bacillus subtilis and 50-70 parts of medical stone. The feed additive for producing the selenium-rich beef can prevent various diseases of cattle and provide safe and nutritional healthy food for citizens, and is optimal food and way for selenium supplement of the whole people, thereby having an important practical significance.

The invention relates to the field of animal husbandry additive preparation, in particular to a synthesis method of a urease inhibitor acetohydroxamic acid. The method comprises the following steps: reacting hydroxylamine hydrochloride with ethyl acetate in an alkaline solvent system, and performing extraction by using an organic solvent after the reaction is finished, with the chemical equation being CH3COOC2H5 + NH2OH.HCl -> CH3CONHOH. The synthesis method can realize industrial mass production of the acetohydroxamic acid, and can ensure a high yield and high purity of the acetohydroxamic acid. The solvents used in the production process can be recycled, and the preparation method is green and economical.

The invention relates to a growing and fattening pig feed additive as well as a preparation method and application thereof, and belongs to the field of feed. The additive comprises the following raw materials: a composite detoxifying agent, an enzyme preparation, camphor tree seed powder, plant essential oil, tea saponin, acetohydroxamic acid, activated carbon and a carrier. The additive can promote the growth of growing and fattening pigs and increase the feed intake and the feed conversion efficiency, and also can adjust the immune function of livestock and poultry, adjust the intestinal microecological balance and enhance the disease resistance; and in addition, the additive can reduce the discharge quantity of nitrogen and phosphorus and dissipating quantity of ammonia gas in excrementof the growing the fattening pigs, and reduce pollution to the environment by the excrement. During preparation, the raw materials are mixed according to the proportion, the operation is simple and rapid and the condition controllability is high. After the additive is added into growing and fattening pig feed, the quality of the growing and fattening pigs can be improved, digestion and absorptionof nutritional materials by the growing and fattening pigs are promoted, the nutrient utilization rate is increased and discharge of manure of a pig field is reduced.

The invention discloses application of farnesene in preparation of a plant-derived urease inhibitor, and belongs to the technical field of urease inhibitors. The compound can effectively inhibit the activity of concanavalin urease and soil urease, and the effect of the compound can be equivalent to that of a commercial urease inhibitor acetohydroxamic acid. The urease inhibiting substance provided by the invention is derived from plants, has the characteristic of'green 'of a natural product, is high in biological safety, simple and stable in chemical structure and remarkable in urease inhibiting effect, can solve the problems of high toxicity, easiness in degradation and poor stability of a conventional chemically synthesized urease inhibitor, and has a wide application prospect. Meanwhile, a new thought is provided for creating a biological and ecological technology for efficiently inhibiting rapid hydrolysis of farmland urea and improving the utilization rate of urea nitrogen fertilizer, and good application value and development prospects are achieved.

This invention provides that (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid (captopril) possess potent in vitro urease inhibitory potential with 95.00% inhibition and IC₅₀=16.6±1.52 μM, when compared to the standard inhibitor i.e. acetohydroxamic acid (IC₅₀=41.5±1.50 μM).