The invention provides a TiO 2 Microwave-based ceramic substrate material and its preparation method and application, it is composed of two crystal phases, the ceramic main crystal phase is rutile TiO 2 , the second crystal phase is MgTi 2 O 5 ; Ordinary oxide ZrO 2 , Nb 2 O 5 , SnO 2 Enter TiO as a dopant 2 A solid solution is formed in the crystal lattice; MnCO 3 , CoO, CuO, ZnO, Al 2 O 3 As a dopant in ceramics, it plays a role in improving the quality factor of ceramics. The general chemical formula is Ti 1‑x A x O 2 +yMgO+zB, its preparation method includes batching, ball milling, granulation, molding, sintering, and the TiO prepared by the method of the present invention 2 The microwave-based ceramic substrate material has a high Q×f value (20000~40000), high dielectric constant (80~95) and serialized dielectric constant temperature coefficient (‑550~‑900) through laboratory research and testing. The composite ceramic of the invention is suitable for making substrate materials of microwave capacitors, and can also be used for making materials of adjustable microwave devices such as microstrip filters.