The invention discloses a cough and asthma relieving traditional Chinese medicine mixture and a preparation method of the mixture. The mixture comprises 10-16g semen armeniacae amarae, 12-20g pummelopeel, 10-18g radix angelicae, 10-18g tangerine peel, 8-15g poria cocos, 10-16g prepared pinellia ternata, 6-10g liquorice, 6-10g radix peucedani, 15-22g radix clematidis, 6-12g platycodon grandiflorum, 12-20g Chinese angelica, 12-20g semen raphani, 2-2.8g fructus gleditsiae, 12-20g rhizoma paridis, 8-15g bombyx batryticatus, 8-15g allium macrostemon, 8-15g honey snakegourd peel, 12-20g spina gleditsiae and 12-20g dandelion. The preparation method of the mixture comprises the steps of distilling mixed coarse powder of the pummelo peel, the radix angelicae, the tangerine peel, the radix peucedani and the Chinese angelica to extract volatile oil, heating, boiling and extracting filtration residue after distilling and the other raw materials for twice, merging and adding distilling filtrate and boiling and extracting filtrate into sucrose, taking supernate, concentrating the supernate to 1000mL, and adding hydroxybenzene ethyl ester and the volatile oil to form the finished product. The mixture has the advantages of stable and definite curative effect, low price, no toxic or side effects on a human body and obvious treatment effect.