The invention belongs to the technical field of daily chemical products and specifically relates to a clothes-washing gel bead and a preparation method thereof. The clothes-washing gel bead provided by the invention contains the following components by weight percent: 30-75% of fatty alcohol-polyoxyethylene ether, 5-15% of glycerinum, 10-20% of propylene glycol, 8-15% of potassium laurate, 5-20% of fatty acid methyl ester ethoxylate, 5-15% of deionized water, 1-5% of acrylic acid-acrylate copolymer, 1-5% of organic silicon compound, 1-5% of essence, 0.2-0.8% of complex enzyme, 0.1-0.6% of microcapsule essence, 0.1-0.5% of silver ion compound, 0.1-0.5% of glutamic acid N,N-tetrasodium acetoacetate, 0.01-0.2% of preservative, 0.001-0.005% of pigment and 0.05-0.2% of citric acid. The clothes-washing gel bead provided by the invention is efficient and safe, has long-lasting fragrance, is sterilizing and has a softening function.