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55 results about "Metabolic efficiency" patented technology

Metabolic efficiency is the measure of how well the body utilizes fat as an energy source. Its efficiency can be improved through exercise and nutrition, specifically by: Supporting stable blood sugars by eating more lean proteins, healthy fats, fruits, and vegetables instead of high carbohydrate foods.

Fermentation medium for regulating and controlling target product of clostridium aerovorans and fermentation method of fermentation medium

The invention discloses a fermentation medium for regulating and controlling a clostridium aerovorans target product and a fermentation method of the clostridium aerovorans target product. The medium comprises a basic component and a regulating component, the basic components comprise ammonium chloride, potassium chloride, magnesium sulfate heptahydrate, sodium chloride, monopotassium phosphate, yeast powder, calcium chloride dihydrate, sodium selenite, nickel chloride hexahydrate, biotin, folic acid, pyridoxine hydrochloride, thiamine, riboflavin, nicotinic acid, D-calcium pantothenate, cobalamin, para aminobenzoic acid and lipoic acid; the adjusting component comprises sodium tungstate, ferrous sulfate and sodium molybdate, sodium tungstate and ferrous sulfate have a forward adjusting effect on increasing the yield of acetic acid, ethanol and butanol in the target product, and sodium molybdate has a reverse adjusting effect on the target product. By optimizing the proportion of trace elements in the culture medium, the clostridium metabolism efficiency is improved, synthesis of a target product is regulated and controlled, and the method is particularly suitable for industrial production of acetic acid, ethanol, butanol and the like.
Owner:NANJING SHIQI BIOCHEMICAL TECH CO LTD

Mutton sheep quantitative intelligent feeding management system based on Internet of Things

The invention relates to the technical field of intelligent animal husbandry, and discloses a mutton sheep quantitative intelligent feeding management system based on the Internet of Things. Comprising a multi-modal sensing module, an edge computing gateway, a metabolic efficiency feedback factor computing unit, an individual nutrition digital twin modeling unit, an active disturbance response verification mechanism execution unit, an intelligent feeding terminal and a group knowledge evolution module. According to the system, an individual nutrition digital twinborn modeling unit is adopted and is combined with an online reinforcement learning algorithm, and an accurate feeding decision is generated according to a metabolic efficiency feedback factor and a nutrition elasticity coefficient matrix; and an active disturbance response verification mechanism execution unit applies controllable tiny disturbance when the model is uncertain, and an elastic coefficient matrix is dynamically updated. According to the method, the physiological state of the individual is sensed in real time by using multi-modal data, dynamic closed-loop control based on metabolic efficiency is realized, the cold start problem of the new individual is solved through knowledge distillation, and the feed conversion efficiency and the culture benefit are remarkably improved.
Owner:ZHUMADIAN XIANYUAN ANIMAL HUSBANDRY CO LTD

Composition for regulating sleep rhythm homeostasis, preparation method and application thereof

The invention discloses a composition for regulating sleep rhythm homeostasis as well as a preparation method and application thereof. The composition for regulating the sleep rhythm homeostasis is prepared from the following components in percentage by weight: 5 to 18 percent of polydextrose, 9 to 15 percent of galactooligosaccharide, 1 to 10 percent of inulin, 0.4 to 2 percent of gamma-aminobutyric acid, 0.8 to 2.2 percent of L-theanine, 0.1 to 3.5 percent of magnesium citrate, 2 to 21 percent of semen ziziphi spinosae extract, 1 to 10 percent of poria cocos extract, 0.5 to 2 percent of pericarpium citri reticulatae extract, 0.3 to 1 percent of liquorice root extract and 15 to 40 percent of maltodextrin. 5-18% of coconut oil powder MCTs, and 0.5-2% of a lily extract. According to the application, a magnesium MCTs shell-core structure is delivered by maltodextrin to form a mitochondrial piezoelectric engine so as to improve prebiotics, promote flora metabolism efficiency and energy supply feedback, activate intestinal pheochromophilic cells and improve SLC6A4 gene expression so as to improve synthesis of 5-hydroxytryptamine in the brain and activate GABA energy neurons; meanwhile, through the spina date seed and poria cocos quantum dots and a pericarpium citri reticulatae and liquorice pi-pi stacking network, the blood-brain barrier penetration rate is greatly increased, and hypothalamic CRH release is adjusted.
Owner:XISHUANGBANNA SHENGZEYAO BIOENGINEERING CO LTD

Excrement weight change and panda estrus cycle correlation modeling method and system

ActiveCN120409076AAnimal reproductionSensorsProgesterone metabolismArtificial insemination
The invention provides an excrement weight change and panda oestrus cycle correlation modeling method and system, and relates to the technical field of panda breeding, and the method comprises the steps: obtaining basic monitoring data of female panda individuals; performing fiber metabolism characteristic extraction according to the daily excrement weighing value to obtain a bamboo fiber metabolism efficiency sequence; performing matrix construction according to the metabolic efficiency sequence and the serum progesterone concentration detection value to obtain a progesterone-metabolic coupling matrix; correcting according to the natural season classification label to obtain an inhibition factor; identifying according to the progesterone-metabolism coupling matrix and the inhibition factor to obtain an estrus critical state characteristic value; and performing model construction according to the metabolic efficiency sequence, the progesterone-metabolic coupling matrix, the inhibition factor and the estrus critical state characteristic value to obtain a panda estrus window dynamic prediction model. According to the method, the missing rate of artificial insemination window identification is reduced, and the breeding efficiency of endangered species is greatly improved.
Owner:CHENGDU RES BASE OF GIANT PANDA BREEDING

Linalool engineering bacterium and application of linalool engineering bacterium in fermentation production of linalool

The invention discloses a linalool engineering bacterium and an application of the linalool engineering bacterium in fermentation production of linalool, and the linalool engineering bacterium is escherichia coli and contains a plasmid pJBEI-MVA and a plasmid pET-AgGPPs-MaLIS. The microbial fermentation technology is utilized, the resource limitation is overcome, the production process is controllable, the period is short, and the green production concept is met. The optimized culture medium formula and material supplementing strategy can effectively relieve the toxicity of linalool and improve the metabolism efficiency and stability of the strain. The purification process is simple, high-purity linalool is obtained through reduced pressure distillation, and the high-end application requirements of spices, medicines and the like are met. In addition, energy consumption and process complexity are reduced, production cost is reduced, economic benefits are improved, the method is suitable for industrial production, and an efficient solution is provided for sustainable supply of linalool.
Owner:BAYECAO HEALTH IND RES INST (XIAMEN) CO LTD +1

Multi-stage fermentation method for improving activity and stability of thalli

The invention discloses a multi-stage fermentation method for improving thallus activity and stability, and particularly relates to the technical field of microbial fermentation. Dynamically dividing a fermentation period into a plurality of metabolic staging sections based on the multi-source physiological characteristic parameter set; constructing a multi-stage environment regulation and control model, taking the optimal control parameter vector of each stage as a control target, combining a real-time feedback signal set, and carrying out environment factor regulation through a model prediction control algorithm; calculating a thallus activity improvement rate and a fermentation stress anomaly index in real time, performing cross-batch correction on the multi-stage environment regulation and control model after fermentation is finished, and outputting an optimized parameter template for next fermentation calling; the dynamic self-adaptive control of the fermentation system can be realized, the thallus metabolism efficiency, the process stability and the fermentation repeatability are improved, and the method is suitable for industrial large-scale microbial fermentation production scenes.
Owner:ZHANJIANG YUEHAI AQUATIC PROD BIOLOGICAL

Biological preparation for relieving intestinal discomfort caused by alcohol as well as preparation method and application of biological preparation

The invention relates to the technical field of functional microbial preparations, in particular to a biological preparation for relieving intestinal discomfort caused by alcohol and a preparation method and application thereof.The main technical scheme is that the biological preparation is prepared from, by weight, 5-20 parts of bacillus coagulans, 10-30 parts of pediococcus pentosaceus, 5-10 parts of lactobacillus rhamnosus and 0-20 parts of saccharomycetes. 0-5 parts of bifidobacterium longum and 0-5 parts of lactococcus lactis. By constructing an alcohol metabolism-intestinal protection dual-function synergistic system, specific florae such as bacillus coagulans, pediococcus pentosaceus and lactobacillus rhamnosus are scientifically compatible with functional components such as inulin and L-cysteine, alcohol is efficiently metabolized, and a carbon source is generated; the technical problems of low metabolic efficiency, weak intestinal protection and serious gastric acid inactivation of a traditional product are comprehensively solved.
Owner:CHANGZHOU AISIKANG BIOMEDICAL CO LTD

Recombinant bacillus subtilis with high yield of surfactin as well as construction method and application of recombinant bacillus subtilis

The invention discloses recombinant bacillus subtilis with high yield of surfactin as well as a construction method and application of the recombinant bacillus subtilis, and belongs to the technical field of genetic engineering. According to the invention, non-essential genes are determined through analysis and identification, a simplified engineering strain is obtained, and the highest fermentation yield reaches 11.2 g / L; then, a PTS part sugar phosphorylase gene obtained through screening is transferred into the simplified engineering strain, the metabolism efficiency of carbohydrates is improved, transportation and utilization of the carbohydrates are optimized, a fatty acid transmembrane transporter gene is further transferred, fatty acid uptake is assisted, synthesis of surfactin is facilitated, and the yield of the surfactin is improved. The combination of the two realizes optimization of synthesis of surfactin through a composite carbon source. Compared with a simplified engineering strain, the genetically engineered bacterium obtained by the invention has the advantages that the yield of surfactin is increased by 57.1%, the yield is increased by 2.3 times compared with that of an unsimplified engineering strain EX, and the final shake-flask fermentation yield can reach 17.6 g / L. As an industrial chassis cell of high-yield lipopeptide, the cell has a good industrial application prospect.
Owner:JIANGNAN UNIV +1

Fermentation device based on multi-physics field cooperation and application thereof

The invention provides a fermentation device based on multi-physical field coordination and application thereof. The fermentation device comprises a fermentation tank unit, an annular magnetic field generation unit, a pulsed electric field generation unit and a control unit. The stable and energy-free background magnetic field is provided through the permanent magnet array, the background magnetic field and the pulsed electric field form synergy, the metabolism efficiency of microorganisms is remarkably improved, the operation cost is low, the device structure is simple, the device can be flexibly deployed, and the device is suitable for large-scale deployment and transformation on an industrial fermentation tank needing long-term and stable operation; a static background magnetic field generated by the permanent magnet is highly stable, is not influenced by fluctuation of a power grid, and is mutually independent and non-interfering with the distribution of a pulse electric field, so that the reliability and repeatability of the process are ensured.
Owner:GUANGDONG LIYAN BIOTECHNOLOGY CO LTD

Water treatment method based on resonant frequency conditioning

The invention provides a water treatment method based on resonant frequency conditioning, and relates to the technical field of water treatment.The water treatment method comprises the steps that treatment of drinking water, drinks and the like is achieved through multi-stage resonance regulation and control treatment and the synergistic effect of light, the half-width change is monitored in real time, adjustment parameters are fed back, and the particle size of water molecule clusters is changed; the stability is prolonged to 72 hours or more, a gradient frequency sequence and multispectral photograph are combined, water molecule clusters are decomposed step by step under the constant temperature condition of 20-25 DEG C, the half-width is reduced to 57-61 Hz from 80.05 Hz, the molecular activity is improved by 28.8%, cluster reunion is effectively prevented by combining low-frequency pulse curing and a trace stabilizer, and the stability is improved by adjusting the frequency and light intensity. Therefore, the molecular group water has the advantages that the metabolic efficiency is improved, cell membranes are easier to penetrate or soft mineral substances are retained, the molecular group water is suitable for people needing to take in more mineral substances, and higher bioavailability is provided for application of drinking water and industrial water.
Owner:SHANGHAI WUDI HEALTH TECHNOLOGY CO LTD +1

Vegetable planting device for soilless cultivation

The invention relates to the field of agricultural equipment, and particularly discloses a soilless cultivation vegetable planting device which comprises a water collecting tank, a planting pipe for planting vegetables is arranged on the water collecting tank, a drainage pipeline is arranged on the planting pipe, a supporting frame is arranged on the water collecting tank, and a supply assembly for providing a nutrient solution is arranged on the supporting frame. The supply assembly is communicated with the planting pipe, and a sensing assembly for sensing temperature is arranged in the planting pipe. The soilless cultivation device can automatically adjust and select the nutrient solution according to the temperature of the nutrient solution, so that the temperature balance of the nutrient solution in the planting pipe, the unmanned management effect of soilless cultivation and the automatic temperature adjusting effect are achieved, meanwhile, the liquid level height of the nutrient solution can be adjusted, the liquid level height of the nutrient solution in the planting pipe is made to meet the root requirement, and the planting efficiency is improved. The growth of vegetable roots is ensured, the metabolism efficiency of the roots is improved, the nutrient absorption efficiency of the roots is improved, and the healthy growth of vegetables is facilitated.
Owner:AN HUI XUN FA NONG YE KE JI GU FEN YOU XIAN GONG SI +1

Paliperidone metabolic efficiency evaluation system based on CYP2D6 gene and environmental factors

The invention relates to the technical field of paliperidone metabolic efficiency evaluation, in particular to a paliperidone metabolic efficiency evaluation system based on a CYP2D6 gene and environmental factors. According to the system, the obtained historical data information is preprocessed, so that more effective data information can be obtained, and a model can be trained more effectively by using the data information; meanwhile, a dynamic metabolism prediction module formed by weighting output of each network in a multi-modal feature fusion module by utilizing a gating attention mechanism is trained based on the preprocessed data, so that a gene-environment-PK / PD multi-dimensional model is obtained, various factors of the environment and the gene can be quantified, and multi-modal data are fused; the dynamic evaluation of the metabolic efficiency is further realized; according to the method, the current data information is scored by using the gene-environment-PK / PD multi-dimensional model, and the score is compared with the preset score, so that whether the model evaluation is qualified or not can be quickly judged, and the model evaluation is adjusted when the model evaluation is unqualified, thereby further improving the evaluation accuracy.
Owner:HANGZHOU XINLAN HUIZHI TECHNOLOGY CO LTD

Screening and regulating method of bacterial strain playing carbon monoxide metabolism role

The invention discloses a method for screening and regulating strains playing a carbon monoxide metabolism role, belongs to the technical field of microorganisms, and solves the problem that in the prior art, the screening effect of microorganisms playing the carbon monoxide metabolism role is not ideal enough. The method comprises the steps of enrichment and purification of strains, morphological identification of the strains, molecular biological identification and metabolism of the strains. According to the method, the modern biotechnology is fully utilized, aiming at the technical defects that the activity of carbon monoxide dehydrogenase is restricted by the concentration of trace element Cu < 2 + > and the metabolic efficiency of the strain is unstable, the optimal Cu < 2 + > concentration threshold and the metabolic efficiency are determined, the contradiction between high-concentration Cu < 2 + > toxicity inhibition and low-concentration enzyme activity insufficiency is solved, and the optimal metabolic growth condition of the strain is determined.
Owner:XIAN UNIV OF SCI & TECH

Mycelium extracted from ganoderma lucidum and preparation method of culture medium of mycelium

The invention relates to a mycelium extracted from ganoderma lucidum and a preparation method of a culture medium of the mycelium, belongs to the technical field of mycelium extraction, and aims to solve the problems that in the prior art, ganoderma lucidum mycelia grow slowly and are prone to pollution, the content of effective components is unstable, and molecular identification is difficult. The invention provides the solid culture medium prepared from the saussurea involucrata purple yellow extract, the extract is formed by combining effective components of saussurea involucrata and sodium alginate, the growth rate and metabolism efficiency of ganoderma lucidum hyphae can be improved, active substances such as polysaccharides and triterpenes are effectively enriched, and the yield of the ganoderma lucidum hyphae is increased. Meanwhile, the stress resistance and the survival rate of the mycelium under the stress conditions of oxidative stress, pathogen invasion and the like are enhanced, the pollution risk in the culture process is reduced, the biosynthesis efficiency and the extracellular secretion level of key secondary metabolites are improved, the immunocompetence and the bioavailability of the product are further improved, and the production cost is reduced. And a stable and reliable technical support is provided for large-scale and high-quality production of ganoderma lucidum.
Owner:JUNZHIYUAN (CANGZHOU) BIOTECHNOLOGY CO LTD

Small-sized aerobic fermentation equipment

PendingCN122502217AOxygen metabolismBiology
This invention relates to the field of aerobic fermentation equipment for organic waste, specifically a small-scale aerobic fermentation device, including a fermentation cylinder, aeration components, aeration plates, and porous permeation plates. The device employs a layered aeration structure, coupled with an adaptive anti-clogging unit, a vibrating aeration top cover, and a wall-mounted jet structure. This fundamentally solves the problems of easy clogging of aeration holes and uneven oxygen supply in traditional equipment. Through a combination of bottom aeration, wall-mounted oxygen supplementation, and material disturbance, oxygen supply is achieved without dead zones inside the fermentation cylinder. The sawtooth stirring blades increase the air gap between materials, significantly improving the aerobic metabolic efficiency of microorganisms and effectively shortening the fermentation cycle. Simultaneously, a hydraulic circulation component is added to pump highly active bacteria and nutrients from the bottom back into the upper material layer, achieving uniform distribution of bacteria and full utilization of nutrients. This solves the problems of large differences in the maturity of the upper and lower layers and nutrient loss in traditional fermentation, improving the fertility and uniformity of the finished organic fertilizer.
Owner:BEIJING CHUANGZHEN ENVIRONMENTAL TECH CO LTD

A wastewater co-metabolic treatment method based on MABR

PendingCN122380553ABiotechnologyBiofilm
The application relates to the sewage treatment technical field and discloses a wastewater co-metabolic treatment method based on MABR, gaseous primary substrates and air are introduced into the membrane cavity of the MABR reactor, and the gaseous primary substrates include C1-C4 hydrocarbons. The gaseous primary substrates and the air are diffused through the membrane cavity to form a microenvironment with high concentrations of gaseous primary substrates and dissolved oxygen on the outer surface of the membrane, so that the functional bacteria are enriched and grown; the gaseous primary substrates and the oxygen are diffused from the inside of the membrane cavity to the outside, which is beneficial to the utilization of the gaseous primary substrates by the functional bacteria, avoids the competition and consumption of the gaseous primary substrates by the heterotrophic bacteria in the liquid phase, ensures that the functional bacteria in the biofilm obtain stable nutrition supply, and greatly improves the co-metabolic efficiency.
Owner:CHINA THREE GORGES CORPORATION

A method for improving the stress resistance of fallen seedlings of the Oriental Wind Snail.

PendingCN122319973AFloraDigestion
This invention provides a method for improving the stress resistance of fallen larvae of the Oriental Wind Snail, relating to the field of Oriental Wind Snail farming technology. The farming process is as follows: (1) After cleaning the farming pond and exposing it to the sun, a layer of sieve cloth and sand is laid on the bottom of the pond in sequence, seawater is injected, and compound probiotic liquid is sprinkled; (2) The fallen larvae along with the attached sand are transferred to the farming pond. For the first 15 days after the transfer, they are fed compound feed, and after 15 days, they are fed compound feed and fresh feed; (3) During the farming period, an anti-stress agent is administered every 3 days. This invention guides the fallen larvae of the Oriental Wind Snail to adapt to the farming environment by controlling environmental conditions, reducing the stress impact caused by environmental changes; by using appropriate compound feed and anti-stress agents, the growth and development of the immune organs of the fallen larvae can be effectively promoted, as well as the balance of intestinal flora can be regulated, promoting the digestion and absorption of nutrients, improving metabolic efficiency, enhancing the body's immunity, thereby improving their stress resistance and effectively reducing mortality.
Owner:GENGHAI MUYANG (HAINAN) INVESTMENT CO LTD

Fermentation device for chicken feed processing protein additive

The invention discloses a chicken feed processing protein additive fermentation device which comprises a fermentation tank, a valve and a cover plate, the valve is mounted at the bottom of the fermentation tank and discharges chicken feed in the fermentation tank, and the cover plate is mounted on the outer edge of the fermentation tank through a hinge and seals the fermentation tank to achieve anaerobic fermentation of the chicken feed. A compaction mechanism is installed in the center of the cover plate, a driver is installed on the upper surface of the cover plate, the driver drives the compaction mechanism to rotate to compact chicken feed stored in the fermentation tank, a support is installed on the left side of the upper surface of the cover plate, and a pressure relief mechanism is installed at the top of the support. The feed density is effectively increased, air in gaps of the feed is thoroughly discharged, a suitable breeding environment is provided for anaerobic beneficial bacteria, the activity and metabolism efficiency of the anaerobic beneficial bacteria are remarkably improved, breeding of aerobic infectious microbes is inhibited from the source, then the palatability of the fermented feed is improved, the digestive tract disease risk of chicken flocks is reduced, and healthy growth of the chicken flocks is promoted.
Owner:JINGZHOU HEMEIHUA BIOTECHNOLOGY CO LTD

Method for detecting higher alcohols in serum and application thereof

PendingCN121385149AComponent separationTriple quadrupole mass spectrometryMetabolic kinetics
The invention belongs to the technical field of chemical analysis and detection, and particularly relates to a method for detecting higher alcohols in serum and application of the method in metabolic kinetic analysis of alcoholic beverages. In order to realize the effective separation and synchronous detection of fatty alcohol, aromatic alcohol and isomers thereof, reduce the volatile loss of higher alcohol and the use amount of a sample and reduce the serum matrix effect, the method comprises the following steps: performing pretreatment extraction and derivatization on drunk serum; high performance liquid chromatography-triple quadrupole mass spectrometry is adopted to detect higher alcohols in serum after drinking and the content of the higher alcohols. Results prove that the detection method disclosed by the invention has the advantages of low sample amount, high precision and accuracy, low matrix effect and low detection limit. The detection method disclosed by the invention is used for detecting the content of ethanol and higher alcohol in serum in the metabolic kinetics analysis of the alcoholic beverage, so that the alcoholic beverage with excellent metabolic efficiency can be screened, and data support can be provided for the evaluation of slow drunkenness, fast sobering and light hangover.
Owner:LUZHOU LAOJIAO CO LTD +1

Composite material containing functional microorganisms and iron-doped carbon quantum dots as well as preparation method and application of composite material

The invention provides a composite material containing functional microorganisms and iron-doped carbon quantum dots as well as a preparation method and application of the composite material. The composite material containing the functional microorganisms and the iron-doped carbon quantum dots comprises inner core particles and a polymer protection layer wrapping the outer surfaces of the inner core particles; the inner core particle comprises a hydrogel carrier loaded with functional microorganisms and iron-doped carbon quantum dots. By utilizing the size effect of the iron-doped carbon quantum dots and the catalytic characteristics of similar enzymes, functional microorganisms are effectively induced to carry out extracellular electron transfer, and the metabolism efficiency is improved; the external polymer protection layer enhances the adhesion of the interface and assists the long-acting slow release of the internal functional microorganisms at the same time. According to the composite material provided by the invention, the yield of active oxygen is remarkably increased through cascade catalysis of organisms and nano-enzymes, the problems that a traditional microbial agent is easy to lose, low in metabolic activity, not lasting in remediation effect and the like are solved, and an efficient and stable bioremediation material is provided for treatment of bottom mud in a water body environment.
Owner:NANJING FORESTRY UNIV

Compositions and compounds containng ketone bodies and / or ketone body precursors and one or more amino acids

Compositions and methods for administering ketone bodies to a subject include a ketone body or ketone body precursor complexed with or coupled to at least one amino acid. The compositions and methods cause one or more of: weight loss, weight maintenance, reduced blood glucose level, maintenance of blood glucose level, increased muscle and physical performance, enhanced metabolic and cellular repair, improved detoxification and gut health, targeted bioavailability, sustained release and controlled absorption, increased metabolic efficiency, enhanced cellular uptake, minimized side effects, multifunctional therapeutics, improved focus, improved energy, improved cognitive function, improved mental acuity, treatment of traumatic brain injury, treatment of diabetes, treatment of neurological disorder, treatment of cancer, treatment of inflammatory condition, appetite suppression, anti-aging effects, anti-glycation effects, treatment of epilepsy, treatment of depression, improved performance, improved muscle mass, improved motor function, increased strength, increased metabolism, increased fat loss, increased fat oxidation, improved body composition, and improved mood.
Owner:AXCESS GLOBAL SCIENCES LLC

High screening method for anti-inflammatory components of three-fruit soup based on intestinal flora metabolism model

The invention discloses a three-fruit soup anti-inflammatory component high screening method based on an intestinal flora metabolism model, and belongs to the technical field of traditional Chinese medicine active component screening. Comprising the following steps: constructing a special intestinal flora metabolism model (containing an in-vitro SHIME dynamic simulation system and an in-vivo flora humanized mouse model) of the three-fruit soup, firstly preparing a total extract of the three-fruit soup, different polar parts and a single prototype component, and co-culturing the in-vitro flora to obtain a metabolite; then locking high-activity prototype components and metabolites through a three-level anti-inflammatory activity screening system, and carrying out structure identification, anti-inflammatory mechanism verification, content and metabolic efficiency detection and in-vivo effectiveness confirmation, and carrying out repeated optimization to form a standardized method. The method solves the problems that traditional screening does not consider intestinal metabolism and results are incomplete, direct and indirect anti-inflammatory activity is considered, the screening result is precise and clinically fit, operation is controllable, repeatability is good, and the method can be used for quality control of the three-fruit soup, dosage form improvement and development of anti-inflammatory innovative drugs.
Owner:QINGDAO UNIV OF SCI & TECH

Composition for improving metabolism, preparation method and tea drink

The invention provides a composition for improving metabolism, a preparation method and a tea drink. Relates to the technical field of food. The composition for improving metabolism provided by the invention is prepared from the following raw materials: a mixed composition, a combined strain and a lactic acid bacteria fermentation product, experiments prove that the composition formed according to the formula can significantly improve the activity of proteasomes, the content and the activity are positively correlated, and the mixed composition, the combined strain and the composition of the lactic acid bacteria fermentation product all have obvious promotion effects and obvious synergistic interaction phenomena; the scheme of the invention can significantly reduce the generation rate of AGEs, and the content is in negative correlation with the metabolism efficiency of the human body, so that the scheme of the invention has the ability to improve metabolism.
Owner:SHAANXI ZHENGHUAZE TECHNOLOGY DEVELOPMENT CO LTD

An optimized control system and method for escherichia coli tyrosine production fermentation

The application provides an optimization control system and method for Escherichia coli tyrosine fermentation, and relates to the technical field of bio-chemical industry and microbial fermentation engineering. The optimization control system and method for Escherichia coli tyrosine fermentation comprises the following steps: based on the mixed raw material of carbon source and composite nitrogen source feeding, raw material component data is obtained in real time by using an online spectrum analysis technology, initial environmental parameters are associated by using a multivariate fusion analysis method, a raw material component characteristic code and an optimal starting environmental parameter set are generated, and the adaptability and stability of the fermentation starting stage are improved; a dynamic prediction model based on time series data is used to calculate the pH variation trend in real time, a parameter adaptive control algorithm is used, and the dissolved oxygen control and energy consumption output are optimized in the fermentation tank, so that the metabolic efficiency of Escherichia coli is improved; and finally, the tyrosine yield reaches 61.7 g / L.
Owner:NANJING NORMAL UNIVERSITY

A modeling method and system for correlating feces weight changes with giant panda estrus cycles

ActiveCN120409076BAnimal reproductionSensorsProgesterone metabolismGenetics
The present invention provides a modeling method and system for associating fecal weight changes with the estrus cycle of giant pandas, relating to the field of giant panda breeding technology. The method comprises the following steps: obtaining basic monitoring data of individual female giant pandas; extracting fiber metabolism characteristics based on daily fecal weight values ​​to obtain a metabolic efficiency sequence for bamboo fiber; constructing a matrix based on the metabolic efficiency sequence and serum progesterone concentration detection values ​​to obtain a progesterone-metabolic coupling matrix; modifying the matrix based on natural seasonal classification labels to obtain an inhibitory factor; identifying the estrus critical state characteristic value based on the progesterone-metabolic coupling matrix and the inhibitory factor; and constructing a model based on the metabolic efficiency sequence, progesterone-metabolic coupling matrix, inhibitory factor, and estrus critical state characteristic value to obtain a dynamic prediction model for the giant panda estrus window. The present invention reduces the miss rate of artificial insemination window identification and significantly improves the breeding efficiency of endangered species.
Owner:CHENGDU RES BASE OF GIANT PANDA BREEDING

Intelligent spiral saline-alkali soil organic fertilizer stirring fermentation method and device

The invention discloses an intelligent spiral saline-alkali soil organic fertilizer stirring and fermenting device which comprises three stirring and fermenting chambers and a spiral conveying device communicated with the three stirring and fermenting chambers which are sequentially arranged in the material flowing direction, and each stirring and fermenting chamber is provided with a feeding port and a discharging port. A temperature control device and an oxygen concentration control device are arranged in the stirring fermentation chamber, a photovoltaic power generation device for supplying power to the temperature control device and the oxygen concentration control device is arranged on the stirring fermentation chamber, and the three stirring fermentation chambers are sequentially arranged to be a heating chamber, a constant-temperature chamber and a cooling chamber in the material flowing direction; and the stirring fermentation chamber independently controls the temperature and the oxygen concentration. The temperature and oxygen concentration of each stirring fermentation chamber are independently controlled, so that the fermentation process can be better matched with the optimal metabolism efficiency of high-temperature aerobic flora, organic matter decomposition is accelerated, and the fermentation efficiency is improved.
Owner:ZHEJIANG HENGZE YUANCHENG TECHNOLOGY CO LTD

Compound oral film agent for protecting nerve cells

The invention discloses a compound oral film preparation for nerve cell protection. The compound oral film preparation comprises a nerve protection type natural product, a compound lipid compound containing phosphoric acid, vitamin or a vitamin-like compound, a nano lipid carrier, a film forming material and pharmaceutically acceptable auxiliary materials. The preparation solves the problems of low absorption and metabolism efficiency and insufficient synergistic effect caused by physicochemical property difference among multiple components, and has the characteristics of convenience in taking and high safety. In-vitro cell experiments show that the film agent can significantly promote the growth of nerve cells, has a significant nerve protection effect, is helpful for treating neurodegenerative diseases and promoting brain health, and has a great application prospect in the aspects of improving memory and attention, and preventing memory degeneration or neural tube malformation.
Owner:南京集萃剂鼎医药有限公司

Method for exciting enzymatic activity in seeds through electromagnetic field

The invention relates to the technical field of electromagnetic field treatment, in particular to a method for exciting enzymatic activity in seeds through an electromagnetic field. Comprising the following steps of 1, seed screening, 2, seed cleaning and disinfection, 3, seed loading, 4, frequency selection, 5, magnetic field treatment, 6, dynamic monitoring, 7, standing treatment and 8, aftertreatment. According to the method, the enzyme activity in the seeds is excited through an electromagnetic field, the enzyme activity is directionally regulated and controlled through a physical means, traditional chemical mutagenesis and hormone treatment are replaced, electromagnetic parameters are set by adopting characteristics according to different target enzymes of amylase and antioxidant enzyme, targeted accurate activation of the enzyme activity is achieved, and the enzyme activity is accurately activated. According to the method, the energy metabolism efficiency and the anti-oxidation defense capacity are remarkably optimized, the method is easy and convenient to operate and wide in applicability, seed treatment of various crops is supported, production convenience is taken into account while the enzyme activity is guaranteed, and an efficient, safe and controllable new seed treatment technology is provided for green agriculture.
Owner:XINJIANG ZHONGHUI AGRI SCI & TECH CO LTD

Compositions and compounds containing beta-hydroxybutyrate and one or more amino acids

Compositions and methods for administering ketone bodies to a subject include a beta-hydroxybutyrate ester of an alcohol, such as a sugar or sugar alcohol. The compositions and methods cause one or more of: weight loss, weight maintenance, reduced blood glucose level, maintenance of blood glucose level, increased muscle and physical performance, enhanced metabolic and cellular repair, improved detoxification and gut health, targeted bioavailability, sustained release and controlled absorption, increased metabolic efficiency, enhanced cellular uptake, minimized side effects, multifunctional therapeutics, improved focus, improved energy, improved cognitive function, improved mental acuity, treatment of traumatic brain injury, treatment of diabetes, treatment of neurological disorder, treatment of cancer, treatment of inflammatory condition, appetite suppression, anti-aging effects, anti-glycation effects, treatment of epilepsy, treatment of depression, improved performance, improved muscle mass, improved motor function, increased strength, increased metabolism, increased fat loss, increased fat oxidation, improved body composition, and improved mood.
Owner:AXCESS GLOBAL SCIENCES LLC