The invention provides a production method of wire rods for high-strength prestressed concrete steel rods. The production method includes: step 1, converter smelting, the carbon content of molten steel at the end of the converter is 0.06-0.15 wt%, the phosphorus content is 0.011-0.020 wt%, and the tapping temperature is 1630-1650°C; step 2, ladle furnace refining, refining is The bit temperature is 1504-1581°C, the refining off-position temperature is 1557-1605°C; Step 3, billet continuous casting, the superheat is set to 20-32°C, and the casting speed is set to 2-2.2m/min; Step 4, For high wire rolling, the billet heating time is more than 2 hours; the temperature setting of the heating section is: the temperature of the upper heating section is 1050-1200°C, the temperature of the lower heating section is 980-1180°C, and the heating section time is not less than 1 hour; the temperature of the upper soaking section is 1000 ~1200°C, soaking lower section temperature is 980~1180°C, soaking section time is not less than 1 hour; rolling start temperature is 960~1000°C; wire rod spinning temperature is 900~950°C. The wire rod for the high-strength prestressed concrete steel bar prepared by the method provided by the invention has stable and uniform quality and no crack defect.