The invention discloses a neutral environment-friendly putty powder which has the air purification property and is free of coating brushing and smooth in appearance. The putty powder is prepared from,by weight, 7-23 parts of ultra-high-strength gypsum, 16-40 parts of calcium carbonate powder, 15-35 parts of calcium carbonate, 6-19 parts of non-calcined kieselguhr, 0.2-1 part of hydroxypropyl methyl cellulose, 2-8 parts of redispersible latex powder, 0.1-0.5 part of starch ether, 1-6 parts of sodium bentonite, 5-15 parts of sepiolite, 2-8 parts of attapulgite and 0.1-1 part of mixed crystal titanium dioxide. Accordingly, the putty powder has the properties of good safety, environmental protection, water resistance, respiratory hygroscopicity, formaldehyde and harmful gas elimination and the like, and has good capacity of improving the quality of the living environment; meanwhile, the surface of the putty powder is smooth, firm and white, other coating or wallpaper can be omitted, and the effects of protecting the environment and reducing the cost can be achieved.