The invention discloses an antifouling cloth preparation method for garment production. The antifouling cloth preparation method includecomprises the following steps: S1, synthesizing tetradecanoyl chloride; S2, synthesizing 2,5-di(tetradecanoate)terephthalic acid; S3, adding terephthalic acid, the 2,5-di(tetradecanoate)terephthalic acid, ethylene glycol and a tetrabutyl titanate catalyst into a stainless steel reaction kettle for esterification to obtain an oligomer 7; S4, after esterification and pre-polymerization in the step S3, increasing the temperature again, and gradually performing vacuumizing for pre-condensation to obtain a polyester high polymer 8; S5, adding the polyester high polymer 8, a dispersant, a defoaming agent and a softener into a screw extruder for melt extrusion, performing melt filtration, liquid phase tackifying, extrusion from spin holes to form strips, side blow cooling, wire oiling and winding forming to obtain polyester high-strength yarns, and spinning the polyester high-strength yarns into antifouling cloth. The antifouling cloth preparation method has the advantages that the method is scientific and reasonable, the obtained antifouling cloth has high waterproofing and antifouling performance and is resistant to cleaning, and the service life of the cloth is prolonged.