33results about How to "Short synthesis path" patented technology

The invention discloses a nitrogen-containing organic phosphorous acid corrosion inhibitor and a synthesis method thereof. The structural formula of the nitrogen-containing organic phosphorous acid corrosion inhibitor is shown by the formula I and the formula II; and the synthesis method of this type of compound comprises the following steps that aldehyde/ketone, melamine, hypophosphorous acid and hypophosphite are subjected to Mancini reaction to produce corresponding nitrogen-containing organic phosphonic acid, nitrogen-containing organic phosphonic acid is used as the acid corrosion inhibitor of carbon steel, galvanized steel and stainless steel, the dosage is 20-500 mg/L, the pH value of a corrosive medium is 0-7, the using temperature is 10-280DEG C, and metal materials can be protected effectively. The synthesis method of the nitrogen-containing organic phosphorous acid corrosion inhibitor has the following advantages that raw materials are easy to get, the price is low, the reaction condition is mild, the synthetic path is short, and the affect on environmental ecology is small.

The invention relates to the technical field of genetic engineering, and discloses a saffron crocus sourced CCD2 mutant, a coding sequence and application thereof, as well as a recombinant yeast strain for producing crocetin. The CCD2 mutant is provided with one or two or above of V120F, Y190K/A, R192V/F, E211A, E212A, T290V, K320A and S323F/A/T locus mutations. A rate-limiting enzyme CCD2 in thesynthesis route of the crocetin is transformed, the crocetin is directly synthesized from beta-carotene by widening the substrate spectrum of the CCD2, and the existing synthesis route of the crocetinis simplified and reconstructed, so that the problem that the total yield of multiple reactions is generally low is solved; and meanwhile, the efficiency of the CCD2 catalyzing an original substratezeaxanthin to synthesize the crocetin is improved, and the yeast strain of the high-yield crocetin is further obtained.

The invention belongs to the field of organic synthesis and provides a preparation method for bromhexine hydrochloride. According to the invention, 2-aminobenzoic ester compounds are taken as raw materials and take part in bromination reaction, reduction reaction, condensation reaction and salt forming reaction, so as to acquire bromhexine hydrochloride. The preparation method has the advantages of short synthesis route, low cost, stable intermediate, no pollution to environment, high purity, high yield, reaching officinal standard and suitability for industrial expanded production.

The invention provides a borane compound used for antibacterial treatment. The borane compound is a dodecaborane substituted amide or a dodecaborane-oxazole. The preparation method comprises: (1) taking a mono-aminated dodecaborane as a raw material and performing an acylation reaction with an acyl chloride compound under the effect of sodium hydride to obtain a dodecaborane substituted amide; and (2) performing oxidative coupling on the dodecaborane substituted amide obtained in the step (1) under the effect of (diacetoxyiodo)benzene to obtain a dodecaborane-oxazole. The invention also provides an application of the borane compound in preparing antibacterial agents. The borane compound has extremely high antibacterial activity on certain Gram negative bacteria, and has a huge prospect.

The invention relates to the technical field of dye adsorbents, in particular to a straw-based amphoteric dye adsorbent as well as a preparation method and an application thereof. The preparation method comprises the following steps: by taking straw as a polymer skeleton, firstly reacting with haloacetic acid in an ethanol-water mixed system, grafting carboxyl on a cellulose molecular chain of the straw to prepare carboxymethyl straw cellulose, then carrying out graft copolymerization on the carboxymethyl straw cellulose and dialkylaminoethyl methacrylate, and grafting tertiary amino on a cellulose molecular chain of the straw, and forming the straw-based amphoteric adsorbent with both anions and cations. The method is simple to operate, mild in reaction condition and short in synthesis path, the used main raw material is waste straw, and the cost is low, so that the obtained product has good environmental friendliness, can be used as an adsorbent for treating anionic dyes and cationic dyes, has the characteristics of strong adsorption capacity, high decolorization rate, good selectivity, short adsorption time, wide application range and the like, is beneficial to industrial practical application, and has important significance in the field of environmental protection.

The invention discloses a method for preparing 4-(6-aminopyridin-3-yl) piperazine-1-carboxylate tert-butyl ester. The method for preparing 4-(6-aminopyridin-3-yl) piperazine-1-carboxylate tert-butyl ester comprises the following steps: 2-aminopyridin, piperazine-1-formate tert-butyl ester and NSP-SA-NHS photo catalyst is added to the solvent, and the light reaction is carried out under the condition of the presence of an oxidizing agent to generate 4-(6-aminopyridin-3-yl) piperazine-1-carboxylate tert-butyl ester. According to the method, 4-(6-aminopyridin-3-yl) piperazine-1-carboxylate tert-butyl ester is synthesized by one step. On the one hand, the synthetic route of 4-(6-aminopyridin-3-yl) piperazine-1-carboxylate tert-butyl ester is effectively shortened, the generation of by-productsis effectively reduced and the yield of the target product is improved. On the other hand, only photo catalyst and oxidizing agent are used, so that the preparation method is safe and environment-friendly and low in cost.

The invention provides a novel method for catalytically synthesizing acetanilide and relates to the technical field of preparation of the acetanilide. The novel method for catalytically synthesizing the acetanilide comprises the following step: enabling aniline and glacial acetic acid to react under the action of a catalyst, wherein the catalyst is a mixture of aluminum borate and manganese dioxide and the weight ratio of the aluminum borate to the manganese dioxide is (2 to 4) to 1. By adopting the novel method for catalytically synthesizing the acetanilide, the blank of a preparation methodfor catalytically synthesizing the acetanilide is filled; the preparation efficiency of the acetanilide is effectively improved, so that the yield of the acetanilide is improved; the novel method hasrelatively great industrial popularization value.

The invention discloses a preparation method of 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline. The preparation method of the 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline comprises the following steps that aniline, piperazine-1-tert-butyl formate and acridine salt photocatalysts are added into a solvent; illumination reaction is performed under the condition of oxidizing agent existence;the 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline is generated. The preparation method of the 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline has the advantages that the 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline is synthesized in one step; on one hand, the synthesis path of the 4-(tert-butyl 1-piperazinecarboxylate-4-yl)aniline is effectively shortened; the generation of by-products is effectively reduced; the target product yield is improved; on the other hand, only photocatalysts and oxidizing agents are used, so that the preparation method is safe and achieves an environment-friendly effect; the cost is low.

The invention discloses front silver paste for a solar cell with low contact resistance and high photoelectric conversion efficiency and a preparation method of the front silver paste, and relates to the technical field of front silver paste for a solar cell and a preparation method of the front silver paste. The invention aims to solve the problems of low tension level of a prepared solar cell and low photoelectric conversion efficiency of the solar cell due to the fact that a binder and a thixotropic agent in an organic carrier used for preparing the conductive paste of the crystalline silicon solar cell in the prior art are more in decomposed residual ash content after the cell is sintered and a solvent is easy to separate out. In the front silver paste for the solar cell with low contact resistance and high photoelectric conversion efficiency, a binding agent is poly (5-hydroxy-2-ethyl pentenoate), a thixotropic agent is pentaerythritol tetra (9-amino-10-hydroxy octadecanoic acid) ester, and a dispersing agent is poly (5-(N, N-dimethylamino)-1, 4-pentanediol monotriethylamine ether. The front silver paste for the solar cell, which is low in contact resistance and high in photoelectric conversion efficiency, can be obtained.

The invention discloses cinnamate derivatives and application of the cinnamate derivatives as tyrosinase inhibitors and gels, and the structural general formula of the cinnamate derivatives is shown in the specification, in the formula, X and Y independently represent any one of O, S and NH, wherein R1 and R2 independently represent any one of H, OH, methoxy, allyl and acetyl; R3 and R4 respectively and independently represent any one of H, OH, methoxy, tert-butyl dimethyl siloxy and carbethoxy, and R3 and R4 are not tert-butyl dimethyl silyl at the same time; and n is an integer from 2 to 5.The cinnamate derivatives disclosed by the invention have obvious inhibitory activity on the activity of mushroom tyrosinase diphenolic enzyme and the content of tyrosinase and melanin in melanoma cells of B16F10 mice, and can be used for preparing the tyrosinase inhibitors. Meanwhile, the cinnamate derivatives can form stable gels in olive oil and can be used as micromolecular gels for cosmeticsand the like.

The invention provides a method for preparation of fluorescent silica nanoparticles. The method includes: a), mixing indocyanine type fluorescent dye with an organic silicon source compound to obtain a precursor solution; b), allowing the precursor solution to react under constant temperature to obtain the fluorescent silica nanoparticles. The water-soluble fluorescent silica nanopartricles are prepared with the one-step method which is performed completely in water phase, so that the method is safe in operation, rapid and convenient, low in toxicity and safe and easy in obtaining raw materials; the water-soluble fluorescent silica nanoparticles are quite good in monodispersity, high in fluorescent property and quantum yield, good in stability, good in water solubility, capable of serving as fluorescence indicators widely applied to biological detection and analysis and hopeful to be used for optical related industrial production such as laser and organic light emitting diodes.

The invention discloses a homogeneous phase ionic liquid catalyzed high-purity diethyl carbonate synthesizing technology, and relates to a catalyzed synthesizing technology. The technology is a catalytic distillation technology for preparing high-purity diethyl carbonate ionic liquid for a lithium battery through ethylene carbonate and alcohol ester exchange by repeatedly using a homogeneous phasecatalyst. In a reaction, a crude product of the initial reaction is a small amount of ethylene carbonate, ethyl alcohol, ethylene glycol, diethyl carbonate and ionic liquid, and a large amount of theethyl alcohol, the ethylene carbonate and the ionic liquid can be recovered and recycled for reproducing diethyl carbonate after the reaction is completed, finally the high-purity diethyl carbonate is obtained; in a reaction process, ethylene glycol is further generated, and the ethylene glycol is bulk chemicals, and can be used as a product for directly separating. In addition, the used catalystcan be repeatedly used, green, pollution-free, and high in catalytic activity. The production technology for diethyl carbonate one-step synthesis is short in synthetic route, simple in technologicalprocess, high in product selectivity and yield, and capable of more effectively producing the diethyl carbonate relative to an existing technology.

The invention provides a high-entropy rare earth co-doped nano low-heat-transfer powder material and a preparation method thereof.The preparation method comprises the following steps that 1, a rare earth source, a boron source and an intermediate are put into a high-pressure reaction kettle, hydrogen is introduced, the temperature is increased to 320-340 DEG C, full stirring is performed for activation, an obtained product is subjected to extraction layering, and precipitation is subjected to suction filtration, water washing and drying to obtain a rare earth-boron co-doped nano low-heat-transfer powder material; then carrying out wet grinding, carrying out spray granulation on the obtained slurry, and carrying out dry grinding on the obtained spherical powder to obtain a precursor; (2) putting the precursor into a rotary furnace for calcining, introducing a hydrogen-nitrogen mixed gas into the rotary furnace, heating to 900-1200 DEG C, preserving heat for 30-450 minutes, and cooling to obtain a primary product; and (3) removing impurities from the head product to obtain the high-entropy rare earth co-doped nano low-heat-transfer powder material. The powder of the high-entropy rare earth co-doped nano low-heat-transfer powder material is dispersed, fluffy and small in particle size, required temperature is low, and energy consumption is low.

The invention provides a method for synthesizing diallyl alcohol compound as 4-(3-methyl phenyl)-1, 6-heptadiene-4-alcohol, which uses allyl zine bromide and mtoluie chloride or mtoluie ethyl formate as raw materials to be reacted at room temperature, extracts via ether, dries and evoprates out solvent and separates via column chromatography to obtain the product. The invention has short synthesis route, high efficiency, high reaction yield (at least 92%), which can eliminate solvent and catalyst and use cheap and non-toxic metal zinc, thereby effectively avoiding the pollution of organic solvent and catalyst to protect environment. The invention has mild reaction conditions (room temperature), short reaction time, simple operation, reduced energy consumption, reduced synthesis cost and significant benefit for industrial production.

The invention discloses a malononitrile phorone fluorine-ion fluorescence probe and a preparation method and application thereof, and belongs to the technical field of analysis and detection. The chemical structural formula of the probe is shown in the description. The malononitrile phorone fluorine-ion fluorescence probe has the advantages of having a good optical property, being capable of highly selectively identifying fluorine ions, having large Stokes displacement and the long fluorescence emission wave length, being high in sensitivity and good in selectivity and the like; the probe is simple in synthesis route, high in yield, easy to separate, high in purity and capable of being used for identifying and detecting the content of fluorine ions in water environment, under the effect between fluorine and the probe, a macroscopic color change is generated, and whether or not the fluorine ions exist in the water environment is conveniently identified by naked eyes; the monitoring speed is relatively high, and interference of other ion elements in the water cannot cause influence. The raw materials are simple and easy to obtain, and the malononitrile phorone fluorine-ion fluorescence probe is low in cost and capable of easily achieving industrialized production, and has good application prospects in environment monitoring and a living body system.