The invention discloses wrinkle removing cream and a preparation method thereof. The wrinkle removing cream comprises the following components in parts by weight: 0.3-1 part of a ginseng root extract,0.2-1.5 parts of a grape seed extract, 0.1-2 parts of a burdock seed extract, 0.2-2 parts of an elm root extract, 0.5-5 parts of a goat milk extract, 1-5 parts of a humectant, 0.1-0.2 parts of a thickening agent, 1-2 parts of an emulsifier, 2-12 parts of an emollient, and 70-90 parts of water. According to the invention, the ginseng root extract, the grape seed extract, the burdock seed extract,the elm root extract, the goat milk extract and other materials are compounded, and the wrinkle removing cream is high in skin permeation speed, smooth and non-greasy feeling is left on the skin, theperoxidation effect of lipidosome can be delayed, cell membranes can be protected, synthesis of type I collagen can be promoted, cell proliferation and wound healing can be promoted, wrinkles can be relieved, and therefore a good wrinkle removing effect is achieved on the skin.