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7 results about "Nephelometry" patented technology

Sample analyzer, protein analysis method, and protein analysis reagent

The invention relates to a sample analyzer, a protein analysis method and a protein analysis reagent. Preparing a first test solution by adopting a to-be-detected sample and the colorimetric method reagent, and detecting the first test solution by adopting a colorimetric method to obtain a colorimetric method detection result of the protein in the to-be-detected sample. Whether turbidimetric detection is carried out or not is judged on the basis of the colorimetric detection result, if not, the concentration of protein in the to-be-detected sample is determined on the basis of the colorimetric detection result, and if yes, a second test solution is prepared from the to-be-detected sample and a turbidimetric reagent, and the second test solution is detected through turbidimetry; and determining the concentration of the protein in the to-be-detected sample on the basis of the turbidimetric detection result and an optional colorimetric detection result. According to the present invention, the protein in the sample can be detected by integrating the colorimetric method and the turbidimetric method, and the linear detection range of the one-time protein detection is improved.
Owner:SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD

Latex enhanced immunoturbidimetry detection reagent for glycosylated hemoglobin and use method of latex enhanced immunoturbidimetry detection reagent

The invention discloses a latex enhanced immunoturbidimetry detection reagent for glycosylated hemoglobin and a use method of the latex enhanced immunoturbidimetry detection reagent, and relates to the technical field of medical examination. The latex enhanced immunoturbidimetry detection reagent for glycosylated hemoglobin comprises a reagent R1 and a reagent R2, wherein the reagent R1 comprises first nano microspheres; and the reagent R2 comprises a second nano microsphere coated with a monoclonal antibody of HbA1c. According to the reagent R2, the nano microspheres are coated with the monoclonal antibody of HbA1c, the stability risk caused by the fact that balance needs to be established for immunoreaction of multiple antibodies and antigens is avoided through the monoclonal antibody, the problem that a glycosylated hemoglobin immunoturbidimetry detection reagent is insufficient in stability can be solved, the nano microspheres are arranged on the reagent R2, and therefore the stability of the glycosylated hemoglobin immunoturbidimetry detection reagent is improved, and the stability of the glycosylated hemoglobin immunoturbidimetry detection reagent is improved. By utilizing the characteristic that the volume of an antigen-antibody conjugate can be increased after the nano-microspheres are combined with the HbA1c monoclonal antibody, the turbidimetric degree of latex is effectively amplified, and the detection sensitivity can be improved.
Owner:ZYBIO INC

Method for measuring an analyte based on nephelometry, sample analyzer and storage medium

ActiveCN112014335BColor/spectral properties measurementsAnalyteTurbidimetry
The embodiment of the present application discloses a method for measuring an analyte based on a turbidimetry method, which comprises the following steps: acquiring at least one prediction time period within a maximum measurement duration and a calibration curve corresponding to the at least one prediction time period; obtaining an estimated concentration value of the analyte according to a reaction degree of the analyte in the at least one prediction time period and the calibration curve corresponding to the at least one prediction time period; determining a final measurement time of the analyte according to the estimated concentration value and a preset corresponding relationship between an analyte concentration value and a measurement time; and determining an actual concentration value of the analyte when the final measurement time is reached. The present application also relates to a measuring device for measuring an analyte based on a turbidimetry method, a sample analyzer for measuring an analyte based on a turbidimetry method and a computer readable storage medium.
Owner:SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD

Determination of non-biological turbidity of cereal brewed cooking wine based on absorbance difference

The invention discloses determination of non-biological turbidity of cereal brewed cooking wine based on absorbance difference, belongs to the technical field of detection, and the cereal brewed cooking wine as important flavoring wine is widely applied in the fields of cooking and catering. The problem of non-biological turbidity is long-standing, and the consumption experience is influenced. The traditional nephelometry and light transmittance method can be used for determining the turbidity of a wine sample, but have certain limitation, and the research establishes a novel simple, convenient and scientific method which takes absorbance difference as a basis and takes EBC turbidity as a reference to evaluate the turbidity of the grain brewed cooking wine, so that the method is expected to be better suitable for determining the turbidity of the grain brewed cooking wine.
Owner:HUZHOU LAOHENGHE BREWING +1

Immuno-nephelometry particle, reagent, test kit and method for detecting target substance

Provided are a particle for immunoturbidimetry, a reagent, a test kit, and a method for detecting a target substance, each of which can detect a trace component in a low concentration region and improve storage stability. The particle for immunoturbidimetry is a particle for immunoturbidimetry including a first resin and titanium oxide, wherein the particle for immunoturbidimetry includes a first layer containing the first resin and a second layer containing the titanium oxide, wherein the second layer is arranged on the outside of the first layer, and wherein the density of the titanium oxide is 3.40 g / cm 3 Hereinafter, and wherein the content of the titanium oxide in the particle for immunoturbidimetry is 10 mass% or more and 80 mass% or less.
Owner:CANON KK

Antibacterial peptide segment intercepted from idgf4 protein of stegomyia and application thereof in preparation of antibacterial medicine

The application discloses an antibacterial peptide segment intercepted from a Stomoxys calcitrans IDGF4 protein and application of the antibacterial peptide segment in preparation of antibacterial drugs. The application screens short peptide fragments in different positions of the Stomoxys calcitrans IDGF4 protein, obtains three candidate peptides through chemical synthesis, and systematically evaluates antibacterial performances of the three candidate peptides. The antibacterial experiment results show that the short peptide with the amino acid sequence shown in SEQ ID No. 2 can effectively inhibit growth of salmonella and staphylococcus aureus at a concentration of 1 mg / mL, the antibacterial effect is confirmed in an antibacterial circle experiment, an enzyme label turbidimetry method and growth curve monitoring, and the short peptide shows stable and significant antibacterial activity, indicating that the peptide segment can be used as a new antibacterial molecule. The application provides a new candidate sequence for development of efficient and low drug resistance risk antibacterial peptides, and has application potential in preparation of clinical antibacterial drugs.
Owner:THE INST OF BIOTECHNOLOGY OF THE CHINESE ACAD OF AGRI SCI