The invention discloses a quinoa and erythropalum scandens meal replacement porridge and a preparation method thereof. The meal replacement porridge comprises the following raw materials by weight: 60-80 parts of quinoa, 25-45 parts of corn starch, 150-200 parts of erythropalum scandens, 20-30 parts of dendrobium nobile, 10-15 parts of gynura divaricata, 15-25 parts of angelica sinensis leaves, 300-500 parts of water, 1-2 parts of vitamin C, 4-6 parts of 4-O-alpha-D-glucopyranosyl-D-glucose, 0.3-0.5 part of polyglycerol polyricinoleate and 0.7-1.2 parts of sodium alginate. The meal replacement porridge is prepared through the steps of raw material weighing, blanching, color protection, pulping, enzymolysis, colloid mill grinding, blending, homogenizing, drying, quinoa pretreatment, compounding, sterilization, packaging and the like. The quinoa and erythropalum scandens meal replacement porridge prepared by the invention has the characteristics of special flavor, high calcium, high protein and the like, can be quickly brewed and eaten by adding a proper amount of water, has an excellent uric acid reducing effect after short-term use, and can be vigorously popularized and applied.