36 results about "Near infrared irradiation" patented technology

The invention discloses a photosensitizer having dual photodynamic therapy effects and a preparation method thereof, wherein the photosensitizer having the dual photodynamic therapy effects has the structural formula described in the specification. With cheap and easy-to-obtain 2-phenylpyridine, iridium trichloride and ethyl benzoate terpyridine as raw materials, and through mild reaction conditions, a target product-iridium complex is simply and efficiently synthesized. Research results indicate that the iridium complex has two-photon excited fluorescence emission in a near infrared region and can be used as a photosensitizer for photodynamic therapy. Confocal development is used for tracking the photodynamic therapy process, the photosensitizer iridium complex can be obviously observed to migrate from cell nucleuses to mitochondria under illumination, and secondary damage of the cells is caused. Animal experiments also prove that the iridium complex has quite good inhibitory effects on tumor growth under a near infrared irradiation condition and has low toxicity to animal bodies in dark environments.

The invention discloses a temperature-sensitive polymer @ graphene oxide capsule drug carrier. According to the capsule drug carrier, silica spheres serve as a template, hollow cross-linked polymer capsules are prepared through reversible addition-fragmentation chain transfer free radical polymerization, and meanwhile, graphene oxide covers the outer surfaces of the capsules. The invention also discloses a preparation method and an application of the temperature-sensitive polymer @ graphene oxide capsule drug carrier. The temperature-sensitive polymer @ graphene oxide capsule drug carrier provided by the invention has photo-thermal, temperature-sensitive and biodegradable properties, and controllable drug sustained release can be achieved by changing the temperature of the carrier through near-infrared irradiation; and the capsule drug carrier not only can show sensitive response to human physiological temperature but also can respond to bio-molecular glutathione in organism, so that the capsule drug carrier, which is decomposed into a small-lamella polymer chain, can be discharged out of a body easily; therefore, the toxic accumulation of the capsule drug carrier in the organism is reduced.

Compositions and methods for administration of local anesthetics that are delivered by a single injection and enable repeated on-demand or high influx analgesia over extended periods have been developed. Pharmaceutical compositions including an effective amount of one or more sodium channel blockers including site 1 sodium channel blockers, optionally one or more alpha-2-adrenergic agonists, which are optionally encapsulated in liposomes, particles or microbubbles, and one or more triggerable elements are provided. The triggerable elements allow delivery of the encapsulated anesthetic drugs when an appropriate triggering stimuli are applied. Exemplary triggering agents or stimuli include near-infrared irradiation, UV- and visible light, ultrasound and magnetic field. In one embodiment, ultrasound is used to trigger a burst of microbubbles to enhance penetration of local anesthetic.

The invention discloses an electrochromic film for effectively modulating sunlight transmittance. The electrochromic film contains Cs x WO 3 A nano-lattice embedded amorphous tungsten oxide composite film, wherein x is 0.06-0.2, the grid point diameter is 80-300nm, the distance between adjacent grid points is 200-600nm, and the grid point height is 30-80nm. The thin film solves the problems that the commercial electrochromic thin film has a narrow adjustable wavelength range of sunlight and cannot independently adjust near-infrared radiant heat. The preparation method first uses laser interference combined with photosensitive sol-gel method to prepare Cs x WO 3 The nano lattice is then filled with an amorphous tungsten oxide matrix in the gaps of the lattice by a sol-gel method to form a composite film. The preparation method has the characteristics of controllable process and large-area film formation, and is very suitable for industrialized mass production.