The invention is applicable to the technical field of nutritious foods. The invention provides a special clinical nutrition formula food for lung cancer and a preparation method thereof. The formula comprises protein, polyunsaturated fat, vitamin A, vitamin C, vitamin E, vitamin D, reduced glutamine, dietary fibers, calcium, iron, copper, magnesium, zinc, selenium, chitosan oligosaccharide, glutamine, soy isoflavone, curcumin and pachymic acid. The formula raw materials are sterilized and are then subpackaged into a bottle to prepare the edible nutritional food. Aiming at the bad situations ofunreasonable diet structure, non-uniform nutrition and the like of lung cancer patients, the nutritional structure of lung cancer patients is improved and the body health condition is improved in anauxiliary manner mainly through diet regulation and control, supplementation of various vitamins and minerals and matching of medicinal and edible food and new resource food.