The invention discloses a preparation method of a high-polymer material for water blocking. The high-polymer material comprises the following raw materials in parts by weight: 260 parts of acrylic acid, 281 parts of 50% sodium hydroxide solution, 26 parts of acrylamide, 392 parts of deionized water, 7.5 parts of ethoxylated pentaerythritol tetraacrylate, 1.5 parts of propylene diamine and 0.8 part of initiator. The preparation method comprises the following steps: adding the acrylic acid, the deionized water and the 50% sodium hydroxide solution into a reactor, and neutralizing; then adding the acrylamide, the ethoxylated pentaerythritol tetraacrylate and the propylene diamine; introducing nitrogen gas to remove oxygen for 10 minutes, and stirring; adding the initiator, and initiating polymerization reaction at 5-8 DEG C to obtain a colloid; and granulating, drying, crushing, and screening. According to the invention, the preparation method is simple in production process and stable in technical performance; the high-polymer material has a high water absorption rate and achieves a high swelling rate when encountering water; and the high-polymer material has a good water blocking effect and favorable heat stability and degradation resistance, is not influenced by a high-temperature environment, and can be uniformly and firmly combined with a substrate.