56 results about "Ricinus sanguineus" patented technology

The present invention is directed to protocells for specific targeting of hepatocellular and other cancer cells which comprise a nanoporous silica core with a supported lipid bilayer; at least one agent which facilitates cancer cell death (such as a traditional small molecule, a macromolecular cargo (e.g. siRNA or a protein toxin such as ricin toxin A-chain or diphtheria toxin A-chain) and / or a histone-packaged plasmid DNA disposed within the nanoporous silica core (preferably supercoiled in order to more efficiently package the DNA into protocells) which is optionally modified with a nuclear localization sequence to assist in localizing protocells within the nucleus of the cancer cell and the ability to express peptides involved in therapy (apoptosis / cell death) of the cancer cell or as a reporter, a targeting peptide which targets cancer cells in tissue to be treated such that binding of the protocell to the targeted cells is specific and enhanced and a fusogenic peptide that promotes endosomal escape of protocells and encapsulated DNA. Protocells according to the present invention may be used to treat cancer, especially including hepatocellular (liver) cancer using novel binding peptides (c-MET peptides) which selectively bind to hepatocellular tissue or to function in diagnosis of cancer, including cancer treatment and drug discovery.

Compositions and methods for treatment of toxin poisoning are disclosed.

An odor absorbing composition is provided comprising zinc salt of ricinoleic acid, a solubility promoter including sodium iminodisuccinate, water and optionally, other ingredients such as perfumes and antifungal agents or bactericides. The zinc ricinoleate can be completely solubilized in water, yet the solution will exhibit low foaming and friability. In addition, the end product may be in the form of a sprayable liquid, a thick liquid capable of clinging to a vertical surface, a gel or solid tablet, a powder, or any other form. The present invention further relates to a method for forming an odor absorbing composition comprising zinc salt of ricinoleate acid, sodium iminodisuccinate and water.

The present invention provides a protein having chain of a ricin-like toxin, a B chain of a ricin-like toxin and a novel heterologous linker amino acid sequence, linking the A and B chains. The linker sequence contains a cleavage recognition site for a specific protease such as those found in inflammatory cells and cancer cells. The invention also relates to a nucleic acid molecule encoding the protein and to expression vectors incorporating the nucleic acid molecule. Also provided is a method of inhibiting or destroying cells having a specific protease, such as cancer cells or inflammatory cells utilizing the nucleic acid molecules and proteins of the invention and pharmaceutical compositions for treating human inflammation and cancer.

The invention provides a method for producing a medium-density fiberboard through branches and trunk of ricinus communis and stalks of miscanthus. The method comprises the following steps: 1, after the branches and trunk of ricinus communis and stalks of miscanthus are mixed, cutting the mixture into pieces; 2, humidifying and preheating the pieces, and performing fiber separation through a defibrator; 3, applying urea resin, an ammonium chloride curing agent and a paraffin waterproofing agent after fiber mixing, and uniformly mixing; 4, drying the fiber mixture; 5, screening the dried fibers, and manufacturing the fiber rough board through hot pressing of a hot press; 6, cooling the rough board, cutting edges and sanding, so as to obtain the finished product medium-density fiberboard. The medium-density fiberboard manufactured through the method provided by the invention is smooth in surface, uniform in fiber texture, moderate in density, good in dimensional stability, good in machining performance, high in bonding strength, static bending strength and plane tensile strength, good in elastic modulus, strong in bolt holding force, and low in moisture absorption and water absorption performance. According to the method, the branches and trunk of ricinus communis and stalks of miscanthus are used to produce the fiberboard, that branches and trunk of ricinus communis are cut down in successive years for updating is achieved and the forest fire caused by stalks of miscanthus is eliminated, and the method is suitable for areas, where ricinus communis and miscanthus grow.

The present invention provides a breeding method for tetraploid ricinus communis. The method comprises: collecting a ricinus communis germplasm resource, performing morphologic character analysis and chromosome ploidy identification, selecting good diploid varieties, carrying out mutagenesis by using colchicine and oryzalin; performing chromosome ploidy identification on F1 generation seeds, selecting homozygous tetraploids, and performing economic character analysis and identification on the F2 generation, so as to breed good tetraploid ricinus communis.