The invention relates to a magnesia-method desulfurization and drying all-in-one machine. The magnesia-method desulfurization and drying all-in-one machine comprises a flue gas dry-method dust remover, a spray drying tower, a cyclone dust collector, a sulfuric acid removing tower, a magnesia pulping tank, a high-pressure spray pump, a magnesia material slurry pump, a circulating conveying pump, aplate-and-frame filter, a high-pressure induced draft fan, a magnesium sulfate storage tank, an aeration draught fan and a control system, wherein the flue gas dry-method dust remover is mutually communicated with an external air source and the spray drying tower; the spray drying tower is mutually communicated with the magnesium sulfate storage tank through the high-pressure spray pump and is mutually communicated with the cyclone dust collector; the cyclone dust collector is mutually communicated with the sulfuric acid removing tower; the sulfuric acid removing tower is mutually communicatedwith the high-pressure induced draft fan, the circulating conveying pump, the aeration draught fan and the magnesia material slurry pump respectively. By adopting the magnesia-method desulfurizationand drying all-in-one machine, on one hand, the flexibility and convenience of equipment utilization can be effectively improved, and installation, construction and operation and maintenance cost of equipment are reduced; on the other hand, the requirements of purifying the tail gas, pre-heating and recycling and preparing a high-purity magnesium sulfate monohydrate product are effectively met atthe same time.