This invention provides a mixed
refrigerant, its preparation method, and its uses. The mixed
refrigerant comprises a first component, a second component, and a third component; the first component is trans-1,2-difluoroethylene (HFO-1132(E)), the second component is monofluoroethane (HFC-161), and the third component is
trifluoromethyl ether (HFE-143a). Compared with the existing R290
refrigerant, the mixed refrigerant has reduced
combustion and explosion hazards; the mixed refrigerant has low GWP (Gross Potential) and is
environmentally friendly, with a GWP ≤ 150, meeting
environmental protection requirements; the thermophysical properties,
refrigeration, and / or
heating cycle performance of the mixed refrigerant are similar to or better than those of R290; the mixed refrigerant can directly replace R290 refrigerant.