The invention relates to a novel self-release fresh-keeping medicine package with a fruit, vegetable and flower fresh-keeping function. The fresh-keeping medicine package comprises a fresh-keeping agent and an explosive bead. A liquid releasing agent is wrapped in the explosive bead. After the explosive bead is broken, the liquid releasing agent is released and is directly contacted with the fresh-keeping agent. The provided fresh-keeping medicine package is very convenient, after the explosive bead in the fresh-keeping medicine package is broken, the fresh-keeping medicine package is directlyput into a package box or a packing bag with vegetables, flowers, or fruits, effective components are released automatically, the fresh-keeping effect is obviously, and moreover, the fresh-keeping medicine package is safe and environmentally friendly, and does not generate any residue. The provided fresh-keeping medicine package has a better fresh-keeping effect, the shelf life is longer, the quality and nutritional value are higher, anti-season sale can be realized more easily, the consumer experience is improved, the sales scope is enlarged, the loss caused by rotting is reduced, the yieldand price are increased, and the value of whole flower, fruit, and vegetable industry is increased.