The invention discloses composite screw type air compressor oil which comprises, by mass, 10-15 parts of raw material synthesis base oil A, 8-12 parts of synthesis base oil B, 20-25 parts of PAG polyether, 20-30 parts of poly-alpha-olefins, 0.1-1.4 parts of alkylated diphenylamine, 0.8-2 parts of 2,6-di-tert-butyl mixed phenols, 0.05-0.3 part of methyl benzene triazole derivative, 0.05-0.3 part of benzene triazole fatty acid amine salt, 10-12 parts of tributyl phosphate, 1.2-2.2 parts of dialkyl dithiophosphate, 0.005-0.05 part of methylsiloxane mixture or liquid ester copolymer, 3-7 parts of dialkyl group naphthalene metal organic sulfonate and 17-19 parts of fat sulphide isobutene. The composite screw type air compressor oil has the advantages of good antioxidation stability, demulsibility and anti-corrosion and anti-rust property, extremely good defoaming performance, excellent viscosity-temperature property and the like. Compared with mineral compressor oil, the energy is saved, oil consumption is lowered, environment pollution is reduced, the service life is prolonged, the performance index reaches the standard of 46# compressor oil, and the compressor oil is used for air compression system mechanical equipment.