The invention relates to an anti-scouring and high-persistence 
pesticide microsphere and a preparation method thereof, wherein the 
wax layer and the micro / nano 
composite structure on the 
plant leaf surface can be effectively utilized, and the retention and the rain wash resistance of pesticides on the 
plant leaf surface are improved through a novel reasonable scientific means so as to provide theimportant significance in the improvement of the 
utilization rate of pesticides and the improvement of the current serious 
pesticide loss situation. According to the invention, a series of 
pesticide microspheres with special topological morphology are fitted, and the topological complementary effect of the pesticide microspheres and the 
crop leaf surface micro-nano structure is utilized to enhancethe retention behavior of the pesticide on the 
plant leaf surface; the results of a series of characterization experiments on the morphology, the slow release property, the universality, the persistence and the 
erosion resistance of the pesticide microspheres prove that the pesticide microspheres can wrap pesticides, such that the persistence and the 
erosion resistance of pesticides on plant leafsurfaces can be remarkably enhanced by utilizing the complementary structure of the microspheres and the 
crop leaf surfaces; and the preparation method can be used for various insecticides, bactericides, foliar fertilizers and 
plant growth regulators, and has high universality.