41results about How to "Has a sustained release effect" patented technology

The invention discloses a thermal-oxidizing-aging resisting polypropylene composite. The thermal-oxidizing-aging resisting polypropylene composite comprises the following components in percentage by weight: 30%-85% of polypropylene, 0-10% of flexibilizer, 2%-10% of compatilizer, 10%-40% of filling agent, 0.1%-0.5% of nucleating agent, 1%-10% of load type functional agent and 0.2%-1.0% of processing agent. Due to the nucleating agent, the polypropylene spherocrystal is refined, the crystallization is uniform and regular and the degree of crystallinity is increased, so that the lattice defect of a substrate is avoided effectively, and the oxygen is prevented from dispersing to the inner part from the surface of the composite freely; due to the compatilizer, the interface bonding force of the polypropylene and the filling agent is improved, so that two phase interfaces are combined tightly, the and the oxygen is prevented from dispersing to the inner part from the surface of the composite freely, and the thermal-oxidizing-aging resistance is improved; and the load type functional agent solves the problem of dispersibility and solvent resistance of an antioxidant and a light stabilizer. The thermal-oxidizing-aging resisting polypropylene composite has a simple preparation method, is high in thermal-oxidizing-aging resisting efficiency and is widely applied to the field of household appliances such as electric cookers, microwave ovens, washing machines, dish-washing machines and the like.

The invention provides a preparation method of bionic coating carrying bioactive factors, which is characterized in that: under a catalyzing system of carbodiimide and N-hydroxy-succinamide, Arg-Gly-Asp (RGD) polypeptide chain containing a disulfide bond is grafted onto polyelectrolyte and then is prepared into RGD grafted polyanion electrolyte solution and RGD grafted bioactive-factor-loaded polycation electrolyte solution, the polyanion electrolyte solution is combined with the polycation electrolyte solution carrying the bioactive factors to establish an organic composite coating carrying the bioactive factors on the surface of planting body through a static self-assembling technology. The composite coating solves the bottleneck problem of bioactive factors used surrounding the planting body, can promote the early growth of osteogenesis surrounding the planting body so as to realize the early osseointegration, and facilitates the long-term stability of the planting body. The method is simple to operate, has moderate preparation conditions, is convenient to control and can realize the continuous production.

The invention relates to a polycarboxylate water reducer for ultra-compact concrete for nuclear power and a preparation method of the polycarboxylate water reducer. Every 100 parts of the water reducer comprises components in parts by weight as follows: 50-55 parts of a dispersing ether type polycarboxylate water reducer, 20-25 parts of a slump retaining ether type polycarboxylate water reducer, 3-5 parts of a retarder, 0.01-0.05 parts of a defoaming agent, 1-3 parts of a water retaining agent, 1-2 parts of a shrinkage reducing agent, 0.1-0.3 parts of a preservative and the balance of water. The components are uniformly mixed in parts by weight during preparation. Compared with the prior art, the water reducer has the advantages as follows: concrete workability and liquidity are improved, a temperature peak value and a shrinkage value of the concrete are reduced, the internal porosity of the concrete is reduced, the self-compacting performance and the durability of the concrete are improved and the like; besides, the preparation method is simple, raw material sources are wide, the cost is low, and the water reducer is environment-friendly and has the good application prospect.

The invention discloses a natural multi-functional foliage fertilizer. The foliage fertilizer comprises the following raw materials in percentage by weight: 10-30% of Pistacia chinensis extraction solution, 5-10% of amino acid nutrient solution, 1-3% of trace elements, 2-4% of attapulgite, 1-3% of diatomaceous earth, and the balance of water. The invention also provides a preparation method of the foliage fertilizer, the method comprises the steps of taking leaves, buds, twigs and fruit peels of Pistacia chinensis, drying and crushing to fine powder; adding fine powder into the extraction solution at a ratio of fine powder to extraction solution being 1g/(5-40) ml and soaking; after soaking, heating, stirring and extracting, filtering the primary extraction solution and collecting the filtrate; centrifuging the filtrate, collecting the supernatant as the Pistacia chinensis extract solution; taking the raw materials in percentage by weight, mixing the raw material, heating and stirring until the raw materials are fully dissolved. The natural multi-functional foliage fertilizer has the advantages that the foliage fertilizer is natural, green, environmentally friendly and efficient, the yield-increasing effect is obvious, no residues of pesticides and fertilizers occur, the natural multi-functional foliage fertilizer can prevent pests and diseases of plants and is especially applicable to organic agriculture.

The invention is aimed at the synthesis of essence microcapsules. In this method, polyvinyl alcohol is used as the leather material, and rose essence is used as the core material, and the essence microcapsules are synthesized by interfacial polymerization, and the reaction is carried out at a certain temperature and pH, after emulsification-polyvinyl alcohol dissolution-polymerization-drying , the product does not need to be purified to obtain the final product essence micro-sachet. The synthesis method of the essence micro-sachet involved in the invention is simple, the obtained essence micro-sachet does not need further purification treatment, and the synthesis process is simple and easy, and the production cost is low.

The invention discloses aluminum oxide-containing polyaniline zinc powder flake epoxy heavy anti-corrosion coating and a preparation method thereof. The coating comprises a component A and a component B, wherein the component A comprises the following components in parts by mass: 35-85 parts of epoxy resin, 0.5-25 parts of polyaniline zinc powder flake, 0.1-10 parts of aluminum oxide, 0.1-5 parts of pigment, 1-15 parts of packing, 0.01-2 parts of anti-sag agent, 0.01-0.5 part of dispersant, 0.01-2 parts of flatting agent, 0.01-0.5 part of deforming agent and 5-40 parts of mixed solvent; and the component B comprises the following components in parts by mass: 40-90 parts of amine curing agent and 10-60 parts of solvent; and the coating is prepared by mixing and stirring the component A and the component B for 1-5 minutes according to a mass ratio being 1: (0.1-1):1. The corrosion resistance, seawater erosion and abrasion resistance, ageing resistance and anti-penetrating property of the coating system are obviously improved; and the coating can be applied to heavy anti-corrosion engineering in fields of petrochemical equipment, pipelines, offshore oil platforms, berthing facilities, ships and the like.

The invention relates to a spandex with long-acting insect-resistant performance and a preparation method of the spandex. The preparation method comprises the steps of feeding a solvent and polyether into a prepolymerization tank, then accurately feeding diisocyanate according to the set NCO/ OH proportion, and carrying out prepolymerization reaction; after the reaction, transferring the product of the prepolymerization reaction into a chain extension tank, and evenly stirring; slowly controlling the dropping of chain extension amine and chain terminator solution at the low temperature to finally form polyurethane-urea solution; feeding an insect-resistant auxiliary agent, an antioxidant, an uvioresistant auxiliary agent, a dyeing auxiliary agent, a delustering agent, a lubricating agent and the like, fully and evenly stirring, and carrying out vacuum defoamation; carrying out dry spinning to obtain the spandex fiber. The spandex prepared by the invention is capable of guaranteeing the performance indexes of the similar conventional products, but also has the long-acting insect-resistant performance.

The invention discloses an ice-condensation-resistant asphalt mixture. The composite material comprises the following components in parts by weight: 150 to 250 parts of aggregate, 50 to 80 parts of mineral powder, 10 to 20 parts of calcium sulfate, 60 to 100 parts of an asphalt matrix, 20 to 30 parts of magnesium chloride, 8 to 15 parts of ethylene glycol, 2 to 6 parts of a silane coupling agent,2 to 6 parts of terpene resin, 3 to 8 parts of zeolite, 6 to 13 parts of diatomite, 1 to 3 parts of polypropylene fiber, 1 to 3 parts of dimethyl silicon oil, 2 to 6 parts of maleic anhydride and 1 to3 parts of a corrosion inhibitor. The ice-condensation-resistant asphalt mixture provided by the invention has the following advantages: the aggregate and the mineral powder have good adhesion to asphalt; high-temperature stability is good; meanwhile, ice condensation resistance is good, so the freezing point of pavements in winter can be effectively reduced; the effect of slow release is achieved, so the ice condensation resistance has certain long-lasting durability; in addition, the ice-condensation-resistant asphalt mixture has high-temperature performance, low-temperature performance, water stability and pavement performance.

The invention relates to a long-acting doxycycline hydrochloride injection for animals and a preparation method thereof. The long-acting doxycycline hydrochloride injection for the animals mainly comprises a main drug doxycycline hydrochloride, compound solvents glycerol methylal, alpha-pyrrolidone and propylene glycol, a sustained-release agent polyvinylpyrrolidone K30-K17 and a pH value regulator ethanol amine or benzyl alcohol. The preparation method comprises the following concrete steps of putting glycerol methylal, alpha-pyrrolidone and a part of propylene glycol into a burdening tank, heating to 40-60 DEG C, stirring while adding polyvinylpyrrolidone, adding doxycycline hydrochloride during stirring, carrying out water cooling to 30-40 DEG C after fully and uniformly stirring, regulating the pH value to 3.0-5.0 by using ethanol amine or benzyl alcohol, replenishing to full dose by using propylene glycol, uniformly stirring, filtering, introducing nitrogen, pouring and sealing in a brown glass bottle, sterilizing by using flowing steam at the temperature of 100 DEG C, carrying out lamp inspection, printing and packing to obtain the long-acting doxycycline hydrochloride injection. The content of the injection is 1-40.0%; the injection has sustained-release and long-acting effects and is given once two days; and therefore, the labour and the cost are saved, the increased stress due to pig catching and injection giving is reduced and the recovery of sick pigs is benefited.

The invention relates to a magnolia biondii pamp volatile oil nanoliposome freeze-dried powder. The magnolia biondii pamp volatile oil nanoliposome freeze-dried powder is prepared by the following steps of: A, preparing a magnolia biondii pamp volatile oil nanoliposome from magnolia biondii pamp volatile oil by a high-pressure homogenization method; and B, preparing the magnolia biondii pamp volatile oil nanoliposome freeze-dried powder from the magnolia biondii pamp volatile oil nanoliposome obtained in the step A by a freeze-drying method, wherein a selected liposome freeze-drying protective agent in the step B is 10 to 15 percent mannitol. The invention further provides a temperature-sensitive magnolia biondii pamp nanogel and a preparation method thereof. In the invention, the magnolia biondii pamp volatile oil nanoliposome is prepared into the freeze-dried powder by the freeze-drying technique creatively so as to improve the stability of a medicament and facilitate large-scale preparation and long-term preservation of the liposome.

The invention relates to the technical field of farmland soil heavy metal pollution remediation and improvement, in particular to a dual-effect alkali- modified charcoal-based vermiculite compound fertilizer for repairing heavy metal pollution of soil and regulating fertility and a preparation method of the dual-effect alkali modified charcoal-based vermiculite compound fertilizer. The compound fertilizer is prepared from the following raw materials in parts by weight: 4 parts of inorganic loading and reduction modification combined biochar and 1 part of urea, the inorganic loading and reduction modification combined biochar is prepared from inorganic loading modified biochar and a KOH solution according to the mass ratio of 1: 1, and the concentration of the KOH solution is 1 mol/L; and the inorganic loaded modified charcoal is prepared from the following raw materials in parts by weight: 5-10 parts of corn straw, 1 part of triple superphosphate and 1 part of vermiculite. A verification result shows that the biochar-based vermiculite compound fertilizer has relatively good adsorption and passivation performance on heavy metals in soil, and has a relatively good fertility effect.

The invention belongs to the technical field of a biomedical material, and in particular relates to an application of dexamethasone sodium phosphate/layered double hydroxides in the aspect of treating asthma and a preparation method of the dexamethasone sodium phosphate/layered double hydroxides. For shortcomings of dexamethasone sodium phosphate, as a conventional glucocorticoid medicine, which is high in toxicity and poor in targeting, the dexamethasone sodium phosphate is loaded by layered double hydroxides, so as to improve a curative effect of the dexamethasone sodium phosphate and reduce toxic and side effects of the dexamethasone sodium phosphate. The prepared dexamethasone sodium phosphate/layered double hydroxides is relatively high in drug loading capacity and has a certain sustained-release effect; and the dexamethasone sodium phosphate/layered double hydroxides can inhibit egg albumin induced airway inflammation in asthmatic rats, and is expected to be applied to treatment of asthma diseases.

The invention discloses a film-coated compound fertilizer for accelerating the growth of a plant root system. The film-coated compound fertilizer is characterized by being prepared from the following raw materials in parts by weight: 54-59 parts of medicine residues, 10-14 parts of bentonite, 9-12 parts of medical stone powder, 8-11 parts of calcium carbonate powder, 4-6 parts of magnesium sulfate, 13-15 parts of triacetin, 67-74 parts of wormcast, 56-60 parts of cattle manure, 10-13 parts of grass carbon, 10-12 parts of perlite powder, 1-2 parts of ammonium molybdate, 1-2 parts of zinc borate, 8-10 parts of soil improvement agents and a proper amount of water. The film-coated compound fertilizer disclosed by the invention is prepared by steps of fermenting the medicine residues, wormcast and cattle manure and then mixing with an inorganic fertilizer, is capable of strengthening nutrition to develop the plant root system; due to adoption of a film coating process, the fertilizer has slow-release effect and is stable in chemical property; in addition, the fiterlizer is free of toxic and harmful substances, safe, environmental-friendly, simple in production process, low in cost and suitable for large-area popularization.

The invention discloses a method for synthesizing a high-efficiency adsorbent by using low-grade magnesite through a one-pot method, and belongs to the field of adsorption materials. Based on the factors that low-grade magnesite contains many impurity components, is high in chemical activity, is a necessary element for plant growth and the like, acid-soluble metal impurities and acid-insoluble slag in the low-grade magnesite are combined with biomass charcoal to prepare the slag and biomass charcoal double-carrier composite metal oxide adsorbent. The magnesium element and excellent phosphorus directional adsorption performance of various impurities are utilized, the biomass charcoal is used as a necessary element for plant growth and is used for adsorbing phosphorus-containing wastewater, the adsorbed adsorbent can be used as a fertilizer, and reuse of phosphorus in the wastewater in the field of fertilizers can be realized. The method is simple to operate and suitable for industrial production.

The invention finds that the plasticity of a material can be enhanced and the problem of poor forming property of a pellet with a high drug-loading rate is solved when a highly-hydrophilic material generally serving as a disintegrating agent in a medicament is used for preparing a sustained-release pellet with high drug-loading rate. In the invention, an applicable highly-hydrophilic material is screened by breaking free from convention, reasonable using amount is researched, the contradiction between sustained release and disintegration of a medicament is avoided, a high-quality pellet is prepared, and a preparation has a sustained release function simultaneously. The invention provides a formula of a para-aminosalicylic acid sustained-release pellet with high drug-loading rate and a preparation process thereof, and provides an enteric-coated oral preparation prepared from the sustained-release pellet.

The invention discloses a lipid carrier with a sustained-release function for polyphenols medicines with low water solubility, a method for preparing the lipid carrier and application thereof. The lipid carrier is a medicine carrier. The medicine carrier is (lamellar-phase and reversed-hexagonal-phase) lyotropic liquid crystal for loading dihydromyricetin, and soybean lecithin, isoamyl acetate, PEG 400 (polyethylene glycol 400) and water are mixed with one another to form the lyotropic liquid crystal. The isoamyl acetate and the PEG 400 are used as mixed oil phase. A mass ratio of the lecithinto the oil phase to the water is 60:5-35:5-35, a mass ratio of the oil-phase isoamyl acetate to the PEG 400 is 2.9-6.2:1, and the concentration of the dihydromyricetin in the liquid crystal is 0.7-9mg/g. The lipid carrier, the method and the application have the advantages that good sustained-release effects can be realized by the medicine carrier for the dihydromyricetin which is a medicine with low water solubility, and the medicine carrier is high in accumulative release rate.