124results about How to "Lower blood sugar concentration" patented technology

The invention discloses a composition and an application thereof in regulating intestinal flora of animals. The composition contains aloe, probiotics and prebiotics, wherein the mass ratio of the aloe to the probiotics to the prebiotics is (6 to 3 to 1)-(6 to 1 to 3). The inventor discovers that the composition disclosed by the invention can effectively promote the proliferation of useful bacteria such as bifidobacterium and lactobacilli in animal intestines, so as to effectively regulate the intestinal flora of animals; therefore, the composition can be used for preventing or treating diabetes on the basis of the effect of the intestinal flora.

The invention discloses a health care product with the function of reducing blood sugar. The health care product comprises L-arabinose, chromium-enriched yeast and any one or more of taurine, Chinese wolfberry extract, L-carnitine tartrate and bitter melon extract. The health care product has the functions of reducing the blood sugar and controlling blood fat simultaneously, has good taste, and is particularly suitable for patients with diabetes.

The invention relates to a compound Chinese eaglewood tea and a manufacturing process thereof. The compound Chinese eaglewood tea is prepared by aquilaria sinensis leaf and stevia rebaudian leaf according to the mixture ratio of 1:9 to 9:1, and the manufacturing process comprises washing, tedding, drying green, piling, rolling, sterilizing, drying and other steps. The invention has the advantages that the stevia rebaudian leaf contains a large quantity of glycosides with high sweetness and low calorie and can neutralize the bitter taste of the aquilaria sinensis leaf without increasing the calorie and the sugar burdens of people who drink the compound Chinese eaglewood tea. Furthermore, the invention adopts the piling process for treating the aquilaria sinensis leaf during the manufacturing process, thereby reducing the bitter taste of the aquilaria sinensis leaf. The compound Chinese eaglewood tea manufactured by the invention has comfortable taste and is easy to be accepted by the people who drink the compound Chinese eaglewood tea.

The invention discloses flour having low glycemic index and a making method thereof. The flour is made from, by weight, wheat flour 35%-45%, soybean flour 35%-45%, buckwheat powder 1%-1.5%, oat powder1%-1.5%, isolated soy protein powder 4%-4.5%, dietary fibers 4%-4.5%, vitamins 0.5%-1.5% and mineral substance 0.5%-1.5%. The flour is based on the low-GI-value (a GI value is below 55) coarse cereal powder, uses the added protein, dietary fibers, vitamins, mineral substance and the like as nutritional materials, has good eating taste and is a high-fiber-content and low-fat healthy food. The flour can delay postprandial blood sugar rise to some degree and is suitable for high-glucose people, patients with diabetes and populations needing low-glycemic-index foods.

A health-care food for preventing and treating atherosclerosis, hypercholesterolemia, hyperlipemia, hypertension, coronary heart disease, angina pectoris, tumor, etc, and balancing the functions of organs is prepared from 10 Chinese-medicinal materials including anemarrhena rhizome, ginger, wolfberry fruit, yam, etc.

The invention discloses low-glycemic-index hollow royal noodles and a preparation method thereof and belongs to the field of food. The low-glycemic-index hollow royal noodles are prepared from, by weight, 25-35 parts of wheat flour, 25-35 parts of soybean powder, 25-35 parts of purified water, 1-1.5 parts of buckwheat flour, 1-1.5 parts of oat powder, 4-4.5 parts of isolated soybean protein meal, 4-4.5 parts of dietary fibers, 0.5-1.5 parts of konjac refined flour and 0.5-1.5 parts of mineral salt. According to the noodles and the preparation method, coarse cereal powder low in GI value which is smaller than 55 serves as a basis, protein, the dietary fibers, the mineral salt and other nutrient auxiliary materials are added, and the noodles are high-fiber and low-fat food and suitable for hyperglycemia people, diabetes patients and crowds requiring low-glycemic-index food.

The invention discloses a high-protein, low-sugar and high-lipid ketogenic meal replacement cake and a manufacturing method thereof. The formula comprises the following by mass parts: 16-35 parts of almond powder, 0-8 parts of flaxseed powder, 16-25 parts of protein powder, 10-25 parts of edible oil, 8-16 parts of dietary fiber, and 6-15 parts of erythritol. The formula of the invention is not only suitable for obese people and hyperglycemic people, but can also regulate the gastrointestinal health of the human body, and can increase the muscle mass of the body and improve the health of the user. Grease, erythritol and cream are mixed firstly, and then eggs and dietary fiber are added, and finally the mixed solid powdery material is added. The method can completely dissolve the dietary fiber, so that the produced cakes have delicate texture without obvious rough feelings.

The present invention relates to a preparation method of a high-quality fermented camel milk with function of auxiliarily lowering blood sugar. The method uses a combination of Lactobacillus plantarum Gr x 16 and other strains as leavening agents to prepare a fermented camel milk with function of auxiliarily lowering blood sugar. Especially the Lactobacillus plantarum Gr x 16, Lactobacillus casei gr x 12, Lactobacillus delbrueckii subsp. bulgaricus gr x 33 and Lactobacillus fermentum gr x 07 are mixed at a ratio of 1 : 1 : 1: 1 (v/v) into leavening agents. The fermentation prepared fermented camel milk is not only good in taste, is relative weak in post-acidification, at the same time has a blood sugar lowering effect on diabetic rats, and also can improve blood lipid levels and increase antioxidant capacity of diabetic rats.

The invention discloses functional food with the hypoglycemic effect and a preparation method thereof. The functional food with the hypoglycemic effect comprises gracilaria agar-agar, sodium alginate, an astragalus extract, a kudzuvine root extract and a mulberry leaf extract according to a certain proportion. The preparation method comprises the following steps: preparing the astragalus extract, the kudzuvine root extract and the mulberry leaf extract; uniformly mixing the gracilaria agar-agar, the sodium alginate, the astragalus extract, the kudzuvine root extract and the mulberry leaf extract in a certain ratio, sealing with capsules, and tabletting by a wet method or making into granules. The functional food disclosed by the invention is reasonable in formula, high in safety and capable of reducing blood glucose level, is used for the adjuvant therapy of diabetic patients and has the effect of improving diabetic complications.

The invention discloses lucid ganoderma-corydalis saxicola compound chewable tablets. The formula of the lucid ganoderma-corydalis saxicola compound chewable tablets comprises 10-25 parts of lucid ganoderma, 10-15 parts of fructus lycii, 2-6 parts of corydalis saxicola, 5-10 parts of fructus momordicae, 20-30 parts of hydroxypropyl methyl cellulose, 5-15 parts of maltodextrin and 1-3 parts of lubricant. A production method of the lucid ganoderma-corydalis saxicola compound chewable tablets comprises the following steps: grinding the raw materials separately and sieving with a 500-mesh sieve to obtain ultrafine powder; combining according to the formula and stirring uniformly; granulating with alcohol by a wet process; drying at 60-80 DEG C until the water content reaches 4-6% by weight; cooling to room temperature, and sieving with a 60-mesh sieve; adding the lubricant and tabletting to obtain the lucid ganoderma-corydalis saxicola compound chewable tablets. The chewable tablets disclosed by the invention have the healthcare effects of clearing heat and removing toxin, protecting and nourishing liver, adjusting immunity, reducing blood sugar and blood fat, resisting oxidation and aging, replenishing vital essence to improve eyesight, promoting longevity and the like.

The invention relates to a health-care noodle which is characterized by comprising 425g-550g of wheat flour, 60g-130g of fresh herba portulacae, 3g-8g of salt and 100g-200g of water. The health-care noodle is prepared by the following steps of washing 100g of fresh root-removed herba portulacae clean, and squeezing juice from the fresh root-removed herba portulacae; adding 150g of water; adding the salt and the wheat flour, and stirring; making noodles by using a noodle maker; drying in the sun or in an oven; and subpackaging and storing. The health-care noodle has the advantage that the health-care noodle contains a large quantity of vitamins, protein, calcium, phosphorus, ferrum, and the like.

The invention provides xylitol probiotics goat milk tablets and a preparation method thereof. The xylitol probiotics goat milk tablets comprise the following components by weight percent: 86-95% of goat milk powder, 2-6% of xylitol, 0.2-0.5% of mannitol, 2-5% of cane sugar, 0.1-1% of freeze-dried probiotics powder, 0.5-1.0% of synanthrin and 0.2-0.5% of microcrystalline cellulose, wherein the freeze-dried probiotics powder is a mixture of probiotics and a composite freeze-dried protective agent, and 1g of probiotics is mixed with 1mL of composite freeze-dried protective agent. The probiotics and the xylitol are fed into the goat milk tablets, so that the goat milk tablets not only are capable of effectively improving the intestinal tract nutrition and flora balance, but also are capable of preventing dental caries and reducing the incidence of upper respiratory infection and bronchopneumonia; the mannitol is fed into the goat milk tablets, so that the survival rate of the probiotics can be increased, and the goat milk tablets have unique nice and cool taste. The goat milk contains epidermal growth factor (EGF), thus having the functions of repairing mucous epithelium cells of intestines and stomach, trachea, skin and the like while promoting the growth of epithelial cells; the xylitol probiotics goat milk tablets are rich in nutrition, convenient to carry and well favored by the public.

A Chinese medicine for preventing and treating atherosolerosis, hypercholesterinemia, hyperlipemia, hypertension, coronary heart disease, angina pectoris, etc is prepared from haw, lophatherum, cassia seed and alismatis rhizome.

The invention belongs to the field of biomedical engineering, and particularly relates to a prussian blue microneedle electrode for blood glucose monitoring, a preparation method thereof, a blood glucose monitoring patch and a preparation method thereof. The prussian blue microneedle electrode provided by the invention comprises a gold microneedle electrode, wherein the gold microneedle electrodecomprises a gold microneedle electrode substrate and a plurality of gold microneedles, wherein the bottoms of the gold microneedles are fixed on the gold microneedle electrode substrate; a prussian blue layer compounded on the surface of the gold microneedle; and a chitosan immobilized glucose oxidase layer compounded on the surface of the prussian blue layer. According to the invention, the problem of tedious work caused by blood drawing test required for diabetes blood glucose monitoring at present is solved; the glucose concentration in the tissue fluid can be rapidly and accurately testedfor a long time only by penetrating the microneedle electrode provided by the invention through the cuticle of the skin, and the microneedle electrode is small in size and convenient to carry, and hasthe potential of serving as a good safe, portable and painless blood glucose electrochemical sensor.

The invention relates to the pharmaceutical technical field. The extraction method of apigenin comprises the steps of 1) enzymatically hydrolyzing celery which is taken as a substrate for 10 hours at 30-35 DEG C through a mixing solution of apigenin which is 33-37% and glucosidase which is 43-47% in mass percentage concentration; and 2) ultrasonically extracting enzymatic hydrolysate obtained from the step 1) through an ethanol solution of 70%, condensing an extracting solution, extracting respectively through petroleum ether and ethyl acetate, evaporating the extracting solution, dissolving through ethanol of 70%, and separating and extracting through a high performance liquid chromatograph. The pharmaceutical composition for treating diabetes consists of apigenin and glucobay at mass ratio of 1: (2-5). The extraction method, which extracts apigenin through a multi-enzymatic process, greatly improves extraction yield. The pharmaceutical composition disclosed by the invention not only can effectively control blood sugar but also can avoid circumstances of low blood sugar and rapid weight loss of a patient due to simple use of a diabetes medicine.

The invention discloses an inulin low-fat yogurt pudding and a preparation method thereof, and belongs to the technical field of food processing. The inulin low-fat yogurt pudding is prepared from the following components by weight percent: 30-40% of yogurt base, 2-10% of inulin, 0.05-0.5% of a thickener, 0.001-5% of a sweetening agent and the balance of water, wherein the inulin is a soluble dietary fiber, can selectively promote growth of colon probiotics, and has the functions of reducing blood sugar concentration, maintaining lipid metabolism balance, improving the bioavailability of mineral elements, enhancing the immunity of the organism, and the like. The inulin low-fat yogurt pudding disclosed by the invention contains the inulin dietary fiber, is low in fat content, and smooth in mouthfeel, has the functions of improving the intestinal microenvironment, controlling blood fat and blood sugar levels, reducing the energy, promoting absorption of a mineral substance and synthesis of vitamins, and is especially suitable for middle aged and elderly people with diseases such as constipation, obesity, hypertension, hyperlipidemia and diabetes mellitus.

The invention discloses indole compounds having insulin-sensitizing activity, process for preparation and use, wherein the compounds and salts have the structural formula of (I), wherein R1 is hydrogen atom, substituted C1-C6 alkyl, substituted aryl alkyl, substituted aromatic heterocyclic alkyl, R2 is alkyl acyl, substituted cycloalkyl acyl, substituted aryl acyl, R3 is hydrogen atom or substituted C1-6 alkyl, R4 is hydrogen atom or substituted C1-6 alkyl, n=0, 1 or 2.

A food for lossing weight of human body is prepared from grains flour 50-80%, edible fibres 10-40 %, plant protein powder 5-10 %, L-carnitine, 0.1-0.8 %, composite vitamine 0.1-0.8%, and mineral elements 1-2% through proportionally mixing and dual-screw extruding out. Its advantages are high effect and high safety.

The invention provides a stem cell preparation for treating diabetes mellitus. The stem cell preparation comprises: stem cells separated and extracted from human blood or tissues and organs and/or islet-like cells induced and differentiated from the stem cells and a cell preservation solution containing 0.5% of heparin calcium, wherein the cell content is 1*10<5> to 5*10<7>/ml. The invention also discloses a preparation method of the stem cell preparation. The method comprises the following steps: (1) separation and purification of the stem cell; (2) in vitro culture of the stem cells or in vitro induction and differentiation of the stem cells to form islet-like cells; (3) diluting the cell obtained in the step (2) by using the cell preservation solution to prepare a stem cell preparation; (4) quality detection of the stem cell preparation. The stem preparation is transplanted into the body and can be differentiated into insulin-secreting cells to secret insulin, and the blood sugar concentration of a person with diabetes is effectively reduced. Thus, a new way is provided for overcoming treatment of the diabetes dependent on the insulin and curing the diabetes once and for all.

The invention discloses a method for constructing and differentiating a pancreatic stem cell line from human insulin. The pancreatic stem cell line is a pancreatic stem cell amplified from human insulin mass and has a multi-lineage differentiation potential. The induced pancreatic stem cell line can be differentiated to form nerve-like cells, fat-like cells, bone-like cells and functional insulin-like cell mass. The functional insulin-like cell mass is transplanted to a body of a nude mouse model suffered from diabetes, so that the blood sugar concentration of the nude mouse model can be reduced and normal blood sugar level can be maintained within one month.

The invention relates to dispersible tablets containing diabetosan and glibenclamide. The dissolving rate of glibenclamide is improved by making colloidal powder or solid dispersion powder of glibenclamide before making tablets. The dispersible tablets can disintegrate quickly, and the dissolving rates of diabetosan and glibenclamide of the dispersible tablets are significantly faster than that of common preparation.

The invention discloses metformin hydrochloride cream and a preparation method of the metformin hydrochloride cream. The metformin hydrochloride cream is prepared from the following components: metformin hydrochloride as the active ingredient, an oil-phase solid ingredient, a consistency regulator, a humectant, an emulsifying agent, a skin penetration enhancer, a pH regulator, a preservative, a stabilizer, an aromatic and water, specifically, the metformin hydrochloride cream is prepared from the following components in percentage by mass: 0.1%-10% of metformin hydrochloride, 1%-15% of the oil-phase solid ingredient, 5%-20% of the consistency regulator, 3%-10% of the humectant, 0.5%-5% of the emulsifying agent, the skin penetration enhancer, the pH regulator, the preservative, the stabilizer and the aromatic with the corresponding mass percentages, the balance of water. The invention provides the metformin hydrochloride cream having good skin penetration effect of the active ingredients and high stability, through optimization of the skin penetration enhancer for the cream, the skin penetration efficiency of metformin hydrochloride is improved, and the side effects caused by the medicine are greatly reduced while the blood sugar concentration in the body of a patient is effectively reduced.

The invention relates to a traditional Chinese medicine composition containing dendrobium huoshanense and having a hypoglycemic effect, and a preparation method thereof. The traditional Chinese medicine composition is composed of Chinese medicinal plant dendrobium huoshanense, ginseng, boxthorn fruit and fructus momordicae, which are compounded together at set weight part ratio. The preparation method comprises the following steps: selecting the Chinese medicinal plant dendrobium huoshanense, ginseng, boxthorn fruit and fructus momordicae according to the set weight part ratio, and mixing and adding resolvent ethanol to prepare a mixed solution; obtaining an extract with an officinal value in the mixed solution through a backflow extraction method; filtering out medicine slag; processing the extract to obtain the traditional Chinese medicine composition provided by the invention; and adding auxiliary medicinal materials to prepare Chinese herbal preparation having the hypoglycemic effect.