Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

49results about How to "Positive and obvious technical effect" patented technology

Laparoscope lens antifogging method and device

PendingCN108992030APlay anti-fog effectSolve the problem of heatingSurgeryEndoscopesAbdominal cavityWater vapor
The invention relates to a laparoscope lens antifogging method, includes a process of heating a laparoscope lens body, repeatedly rubs an outer surface of the laparoscope lens body with a thermochromic rubber pad, heats the laparoscope lens body through utilizing heat generated through friction, on the basis of the heat transfer principle, further heats the lens of a laparoscope and achieves the antifogging effect of the laparoscope lens. The invention further provides a laparoscope lens antifogging device, the laparoscope lens antifogging device comprises the laparoscope, wherein the laparoscope comprises the lens, a body and a handle, the lens is arranged at a front end of the body, the body and the handle are connected, an outer side of the body is provided with a rubber pad, the rubberpad is distributed with thermochromic additive, one side of the rubber pad is provided with an arc-shaped groove, and the arc-shaped groove is matched with the outer side of the body. The laparoscopelens antifogging method and device are advantaged in that the frictional heat generation principle is utilized, the laparoscope lens is heated to the temperature to prevent water vapor in the abdominal cavity from condensing due to coldness before the lens, and thereby the antifogging effect of the lens is achieved, and the laparoscope lens antifogging method and device are simple, fast, economical and practical.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Application of protein DEPDC1 (Dishevelled and EGL-10, Pleckstrin Domain-Containing protein 1) as marker for diagnosing triple negative breast cancer

The invention provides application of protein DEPDC1 (Dishevelled and EGL-10, Pleckstrin Domain-Containing protein 1) as a marker for diagnosing the triple negative breast cancer, and also provides application of miR-26b for preparing a medicine for treating the triple negative breast cancer. The invention also provides application of miR-26b for preparing a medicine for inhibiting DEPDC1 mRNA (Ribonucleic Acid) expression. The invention finds that DEPDC1 expression is obviously higher than a paired para-carcinoma tissue in a triple negative breast cancer tissue. In the triple negative breastcancer cell, overexpression DEPDC1 can accelerate cell growth and tumor formation through FOXM1 (Forkhead box protein M1) expression up-regulation. On the contrary, after the DEPDC1 is knocked down,an inverse function is displayed. In addition, in the triple negative breast cancer, miR-26b serves as a tumor inhibiting factor to directly inhibit DEPDC1 expression and weaken the acceleration function of the DEPDC1 for cell growth and clone formation. The invention points out a new important mechanism for the occurrence, the development, the regulation and the control of the triple negative breast cancer.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Method for tumor marker quantitative determination through metal-wrappage -antibody composite nano particle based on raman enhancement

The invention discloses a method for tumor marker quantitative determination through a metal-wrappage -antibody composite nano particle based on raman enhancement. The method comprises the following steps of: dispersing a metal nano particle included in an inorganic substance or an organic substance or a polymer or a precious metal into a buffer solution and adding an antibody to realize reaction,enabling the antibody to wrap the metal nano particle, thereby obtaining the metal-wrappage -antibody composite nano particle, and dispersing the metal-wrappage -antibody composite nano particle in the buffer solution after washing; and repeatedly preparing various metal-wrappage -antibody composite nano particle solution containing different antibodies and having different concentrations, and uniformly mixing the solution; mixing purified liquid containing a tumor marker with the nano particle mixed solution, after reaction, obtaining a new metal-wrappage -antibody-antigen composite nano particle formed after specific binding of the antibody and the antigen, then, performing transmission spectrum detection, and obtaining concentration of various tumor markers. The method provided by theinvention has the advantages of being simple to operate and highly sensitive and having wide detection intervals and strong specificity. The method can simultaneously perform quantitative analysis forvarious tumor markers, and has great significance in early diagnosis of tumor.
Owner:上海镭立激光科技有限公司

Desilting system suitable for riverway

The invention provides a desilting system suitable for a riverway. The desilting system comprises at least two weir bodies, floating filter strips and ecological floating islands are arranged on the lower course of the weir bodies, the floating filter strips are installed on the lower portions of the ecological floating islands, aquatic plants are arranged in the ecological floating islands, a desilting basin is arranged on the lower course of the filter strips, the bottom of the desilting basin is lower than the bottom surface of a river bed, and an ecology landscape weir is arranged on the lower course of the desilting basin. The multi-stage stepped weir bodies can reduce the flow speed of the bottom layer of the riverway, and sedimentation of silt, particulate matter and other large suspended solids in water is facilitated. The floating filter strips can intercept and adsorb suspended solids in river water. The desilting basin plays a role of a secondary sedimentation tank, the suspended solids in the water are further precipitated. The ecology landscape weir is the end point of the whole desilting system, inflow water overflows to the lower course from the upper ends of the weir bodies, it is ensured that the final outflow water is clear, and the desilting system has a landscape efficacy.
Owner:SHANGHAI TAIHE WATER ENVIRONMENTAL TECH DEV CO LTD

Tumor microenvironment response type gene nano-micelle as well as preparation method and application thereof

The invention provides a tumor microenvironment response type gene nano-micelle. The tumor microenvironment response type gene nano-micelle comprises polyethyleneimine-phenylboronic acid and polyethyleneimine-maleic anhydride-target radical, wherein the mass ratio of the polyethyleneimine-phenylboronic acid to the polyethyleneimine-maleic anhydride-target radical ranges from (1 to 1) to (1 to 2).The invention further provides a preparation method of the tumor microenvironment response type gene nano-micelle. The invention further provides application of the tumor microenvironment response type gene nano-micelle to preparation of a medicine for treating cancers and application of the tumor microenvironment response type gene nano-micelle serving as a medicine carrier. The nano-micelle provided by the invention can efficiently load and transmit RNA (Ribonucleic Acid) and a medicine with a microenvironment response type gene enters a tumor cell target to play a role; the tumor microenvironment response type gene nano-micelle is especially suitable for loading the RNA for carrying out gene therapy on malignant tumor. The preparation method is simple and convenient and is suitable forlarge-scale production.
Owner:SHANGHAI INST OF ONCOLOGY

Method for repairing copper and zinc compound contaminated soil in urban relocation land by using woody plants

The invention provides a method for repairing copper and zinc compound contaminated soil in urban relocation land by using woody plants. One or two or more of poplar, camphor trees, Magnolia grandiflora, Magnolia denudata, ligustrum lucidum Ait, Broussonetia papyrifera, Lagerstroemia indica, Prunus Cerasifera, pomegranate trees, hackberry, mulberry trees, plane trees, Zelkova schneideriana, papayatrees, Cerasus yedoensis, Chinese juniper, cedar and elm are adopted, and are planted in the copper and zinc compound contaminated soil. The invention also provides a fertilizer. Pruned branches andleaves or natural fallen leaves of the trees planted in the copper and zinc compound contaminated soil are collected, air-dried and burned, ash obtained after the burning is dissolved in water, the obtained solution is filtered, and the filtered solution is used as the liquid fertilizer after being diluted. The plants are planted in the copper and zinc combined contaminated soil to purify the soil. The pruned branches and leaves or natural fallen leaves of the planted and survived trees are burned and then dissolved in the water, and the obtained solution is used for supplementing inorganic nutrients in the growth and development process of the plants as the liquid fertilizer, so the method is environmentally friendly and economical.
Owner:SHANGHAI ACADEMY OF LANDSCAPE ARCHITECTURE SCI & PLANNING

Effluent pretreatment system for rain and sewage mixed-flow type pump station

The invention provides an effluent pretreatment system for a rain and sewage mixed-flow type pump station. The effluent pretreatment system comprises an aeration system and a biofilm formation system,wherein the biofilm formation system is arranged at the upper part of the aeration system; the aeration system comprises at least one aeration device; any one aeration device comprises a main pipe and two or more branch pipes; the branch pipes are perpendicular to the main pipe; any one main pipe is connected with an air blower; each main pipe and each branch pipe are respectively provided with two or more aeration holes; the separation distance of the aeration holes is 60 to 120 cm; main pipes and bank lines are arranged in parallel; the biofilm formation system is composed of two or more steel pipes; the bottom parts of the steel pipes are fixedly connected with river bottom; a steel wire rope is arranged between the steel pipes; steel wire ropes are perpendicular to the bank lines; a suspension film is arranged on each steel wire rope; the lower end of each suspension film is fixed through a gabion; and floating balls are arranged on suspension films. The effluent pretreatment system provided by the invention solves the technical problems of high pollution inlet load of a river and large lockage flow rate due to outfall of the rain and sewage mixed-flow type pump station.
Owner:SHANGHAI TAIHE WATER ENVIRONMENTAL TECH DEV CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products