The invention discloses a preparation method of special grape fertilizer capable of increasing the fruiting rate. The preparation method comprises the steps as follows: clay, sodium dodecyl benzene sulfonate and an ethanol solution are stirred, filtration and drying are performed, and pretreated clay is obtained; betaine hydrochloride and water are added to the pretreated clay, sodium hydroxide is added, an obtained material is uniformly stirred and heated, the vacuum degree is adjusted, concentration is performed, fructose and corncobs are added, even mixing, homogenization and spray drying are performed, and pretreated corncobs are obtained; pig manure, edible fungus dregs, papermaking sludge, brewer's grains and biological bacteria are mixed and fermented, the pretreated corncobs, mica powder, expanded perlite, zeolite powder, silica fume, zinc fulvate, manganese fulvate, myricetin, luteolin and compound sodium nitrophenolate are added, an obtained material is uniformly mixed, granulation is performed, and the special grape fertilizer capable of increasing the fruiting rate is obtained.