30results about How to "Improve shelf life stability" patented technology

A two-part self-curing endodontic sealing system comprises a thiourea derivative, such as acetyl thiourea, and a hydroperoxide, such as cumene hydroperoxide. The thiourea derivative is used as a reducing agent and the hydroperoxide is used as an oxidizing agent.

The present invention relates to metal-containing compositions with refractive indices of at least 1.5 comprising a metal-containing precursor unit (MU), a prepolymer unit (PU), and a catalyst or an initiator capable of inducing a combining reaction of ethylenically unsaturated functional groups of the metal-containing precursor unit and reactive functional groups of the prepolymer unit. In another embodiment, the composition comprises MU and a catalyst or initiator capable of inducing a combining reaction of the metal-containing precursor units. Both MU and PU contain additional functional groups, which may be selected to impart compatibility with each other and to produce optically clear films. The metal-containing compositions can be used to produce films or articles having a transmittance of at least 90% and index of refraction in the range of 1.5 to 1.8 in the 400-700 nm range of light and 1.5 to 2.4 in the 150-400 nm range of light.

A polyol pre-mix composition includes a blowing agent having a halogenated hydroolefin, a polyol, a catalyst composition, and an antioxidant. The antioxidant may be, for example, a benzene diol or a benzene triol or other polyhydroxy-substituted aromatic compound, which is optionally substituted with one or more substituents such as alkyl groups. A two-part system for producing a thermosetting foam blend includes (a) a polyisocyanate and, optionally, one or more isocyanate compatible raw materials; and (b) the polyol pre-mix composition. A method for producing a thermosetting foam blend includes combining: (a) a polyisocyanate; and (b) the polyol pre-mix composition.

The present invention relates to a process for forming metal-containing films by applying a photosensitive metal-containing composition on a substrate, drying the photosensitive metal-containing composition, exposing the photosensitive metal-containing composition to a source of actinic radiation and applying a post-treatment to the metal-containing composition. The process also includes exposing the photosensitive metal-containing composition to a source of actinic radiation through a mask or mold and developing the unexposed portion of the composition. Another embodiment of the invention is a metal-containing film, three-dimensional object or article formed by the process. The invention is useful in producing a directly patterned metal-containing film and a microdevice.

The invention relates to a preservation-resisting energy bar which is prepared from the following raw materials in parts by weight: 1000-5000 parts of protein powder, 1500-3500 parts of syrupy, 500-1500 parts of a water-retaining agent, 200-1000 parts of lipid, 500-1000 parts of carbohydrate, 500-2000 parts of a cocoa butter or cocoa butter substitute product and 50-150 parts of pure water. The energy bar made by using the formula and the method provided by the invention is fine and smooth in taste, fragrant and sweet in flavor, convenient to carry over and unlikely to deteriorate and is particularly applicable to special purposes such as long-term wild sports and military training as certain moisture and soft taste are still maintained after being preserved for a long time.

A liquid developer includes a toner particle mainly composed of a resin material, and a nonvolatile insulating liquid, the resin material including an ethylene copolymer, and the insulating liquid including fatty acid triglyceride.

A two-part self-curing endodontic sealing system comprises a thiourea derivative, such as acetyl thiourea, and a hydroperoxide, such a cumene hydroperoxide. The thiourea derivative is used as a reducing agent and the hydroperoxide is used as an oxidizing agent.

Compositions and methods are disclosed which greatly improve the shelf-life of pesticidal agents and especially insecticides. The tendency of the composition to segregate from the solid components is minimized, which improves uniformity throughout the product.

Adhesive compositions effective for bonding runner to metal and containing no more than about 1000 ppm of lead especially adapted to bond vulcanized elastomers to rigid substrates, like metal are disclosed. The adhesives are useful in combination with primer coats, and as one-coat adhesives and provide durable, rubber tearing primary adhesive bonds after exposure to harsh conditions. The adhesives exhibit excellent bond versatility, sweep resistance, and in-can storage stability. In one embodiment, the adhesive compositions of the present invention consist essentially of less than 1000 ppm of lead, at least one diluent as water or organic solvent, a halogen-containing film former, optionally a nitroso compound, brominated dichlorobutadiene, and/or adhesion promoter, and an acid scavenger comprising zinc phosphate.

Disclosed herein are methods for the preparation of a free-flowing, storage-stable fatty acid metal salt product by forming a reactive admixture comprising (a) an unsaturated fatty acid glyceride feedstock; and (b) from about 1 mol to about 3 mol of at least one monovalent metal hydroxide or at least one divalent metal hydroxide; and heating the admixture to a temperature at which said fatty acid glycerides saponify to form fatty acid metals salts; wherein said monovalent metal is potassium; and wherein said divalent metal is selected from the group consisting of calcium, copper, magnesium and zinc. The fatty acid glycerides may be saponified in an atmosphere in which the partial pressure of oxygen has been reduced by an amount effective to provide an improvement in storage stability until a free-flowing, storage-stage product is obtained, or prior to saponification, the fatty acid glycerides may blended with a stabilizing oil that promotes storage stability, or both. Storage stable metal salts of unsaturated fatty acids prepared by the inventive methods are also disclosed.

The present invention discloses a before-running nutrition energy bar and a preparation method thereof, wherein the before-running nutrition energy bar comprises 10-30 parts of maltose syrup, 10-30 parts of high fructose syrup, 15-30 parts of puffed millet, 10-20 parts of puffed corn, 10-15 parts of soybean protein, 4-8 parts of sunflower seeds, 0.8-5 parts of banana powder, 1-8 parts of grease, 0.05-0.5 part of edible salt, 0.01-0.2 part of a ginseng extract, 0.1-1 part of a lily extract, 0.3-5 parts of a common yam rhizome extract, 0.5-2 part of chia seed, 0.25-5 parts of oat-beta-dextran, 0.1-0.5 part ofphospholipid, 0.02-2 parts of natto powder, 5-10 parts of edible coating, and 0.01-0.75 part of edible essence, and material preparation, mixing, molding, cutting and coating production are performed to produce the before-running nutrition energy bar. The before-running nutrition energy bar of the present invention uses the formula of the food having medicine food homology, has the complete nutrition, has effects of before-game tension relieving, yin nourishing, lung moisturizing, yang strengthening and qi supplementing, has characteristics of convenient use and good taste, and is suitable for before-running exercise people requiring energy supplementing and people requiring rapid energy supplementing.

The invention discloses a preparation method of a grease microcapsule. The method comprises the following steps of adding a wall material, an emulsifier and an antioxidant into water, uniformly mixing, shearing and emulsifying to obtain a pre-emulsified liquid, and the wall material being a starch sodium-octenylsuccinate methacrylic acid-N, N-dimethylaminoethyl ester-chitosan copolymer; adding a grease core material into the pre-emulsified liquid, and sequentially shearing, emulsifying and homogenizing to obtain emulsified liquid; sterilizing the emulsified liquid; and carrying out spray drying on the sterilized emulsion, and sieving an obtained powder product to obtain the grease microcapsule. According to the method, the emulsified liquid is subjected to high-temperature sterilization before spray drying, so that the microcapsule is prevented from deteriorating under the action of microorganisms; and the copolymer of starch sodium-octenylsuccinate-N and N-dimethylaminoethyl methacrylate-chitosan is used as the wall material of the microcapsule, so that the high temperature resistance of the wall material is effectively improved, the demulsification phenomenon of the emulsion in the high-temperature sterilization process is prevented, and the embedding rate of the microcapsule is increased.

The invention relates to the technical field of microbial preparations, and provides a three-layer embedding method for improving the stability of lactic acid bacteria, which comprises the following steps: S1, carrying out high-density culture on lactic acid bacteria in a fermentation tank; S2, centrifugally separating bacterial sludge from the fermentation liquor, wherein the water content of the bacterial sludge is 5-50%; S3, uniformly mixing the bacterial sludge and a first-layer embedding protective agent according to a mass ratio of 1: (1-3), wherein the first-layer embedding protective agent is a first-layer embedding protective agent containing 5-50% of skimmed milk powder; S4, uniformly mixing the bacterial sludge and a second-layer embedding protective agent with the mixture in S3 according to the mass ratio of 1: (1-3); S5, mixing the bacterial sludge and a third-layer embedding protective agent with the mixture obtained in S4 according to the mass ratio of 1: (1-3), and then uniformly emulsifying to obtain an emulsion in S5; S6, performing cryogenic granulation on the emulsion in the step S5 by using a liquid nitrogen dripping freezing technology, so that thalli instantly enter a dormant state to obtain cryogenic granules in the step S6; and S7, drying the cryogenic granules obtained in the step S6 until the water content is 3-8%. Through the technical scheme, the problem of poor stability in the prior art is solved.

The present invention is directed to a medicinal composition for treating skin inflammations, fungal/bacterial skin infections and related wounds, and also other skin wounds including those caused by burns. The cream also causes skin rejuvenation through an epithelisation process. The cream comprises:

• a) a biopolymer in the form of Chitosan, b) active Pharmaceutical Ingredients (APIs), in the form of fusidic acid that has been generated in situ from sodium fusidate Hydrocortisone acetate & clotrimazole, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants and d) water. The invention also discloses a process to make medicinal cream containing Fusidic acid formed in situ from Sodium Fusidate by converting it into Fusidic acid under oxygen-free environment. The cream has greater shelf-life and the finer particle size of the API than the conventional creams containing Fusidic acid.

The present invention provides low viscosity energy-activated room temperature polymer compositions, equipment, systems and methods for handling, activating and dispensing the thermodynamically unstable, high solids, activatable liquid compositions.

This invention relates to a reactive silicone composition for forming a hotmelt material, comprising: (A) an organopolysiloxane resin represented by the specific average unit formula; (B) an organopolysiloxane resin free of alkenyl group and represented by the specific average unit formula; (C) a diorganopolysiloxane represented by the specific average formula; (D) an organohydrogenpolysiloxane having two silicon-bonded hydrogen atoms in a molecule; (E) an organohydrogenpolysiloxane having at least three silicon-bonded hydrogen atoms in a molecule; and (F) a hydrosilylation catalyst. The reactive silicone composition can be reacted to form a hotmelt material having excellent shelf life stability, instant adhesion performance by hotmelt process.

The application provides a method for improving the stability of a low-concentration atropine ophthalmic preparation, characterized by controlling the content of the total impurity ≤0.25% and/or a single impurity content of ≤0.05%, as well as a method for preparing the ophthalmic preparation, an atropine ophthalmic preparation prepared therefrom and use thereof in the manufacture of a medicament for preventing and/or treating vision defects.

A point-of-sale custom color system for tinting base paints and stains includes an array of water-only fluid colorants, including at least white, green, blue and red water-only colorants, which can be used to tint water-borne paints and stains. When tinting solvent-borne base paints or stains, at least one siccative is added to the solvent-borne base paint or stains at the point-of sale and a synergist containing one or more surfactants and optional dispersing agents or optional cosolvents is also added to or is a part of the solvent-borne base paint or stains. Collectively, the siccative and synergist enable effective tinting using the water-only colorants and suitable drying characteristics of the solvent-borne paint or stain.

The present invention relates to an aqueous hydrogel composition for topical application to skin or a wound, comprising doxycycline with carboxy-methyl-cellulose, glycerol, citric acid, and at least one pH stabilizer, wherein the composition includes a suspension or dispersion of particles of doxycycline chelated with calcium, said particles have an average diameter less than or equal to about 100 microns, wherein the doxycycline chelated with calcium is present in an amount ranging from greater than about 0.1 weight % to about 3 weight %, wherein the composition includes less than 0.5 weight % 4-epidoxycycline. The present invention also describes methods for making a composition for topical applications as well as methods of treating skin or a wound with an aqueous hydrogel composition comprising doxycycline with carboxy-methyl-cellulose, glycerol, citric acid, and at least one pH stabilizer.

The present invention relates to a liquid formulation of a long-acting human growth hormone conjugate and a preparation method thereof.

The invention provides a nutritional food and a preparation method and an application thereof. The nutritional food of the present invention is a composition made by dietary fibers as a carrier, and supplemented by lipoic acid (LA) or dihydrolipoic acid (DHLA), 1,3-diglyceride (DAG), protein, sterol, vegetable oil and water respectively through an embedding technology. The nutritional food can beused as a health food, in particular to a solid powdery health-care food and has good nutritional health-care value. The nutritional food of the present invention has low cost, unique taste, easy carrying and consumption, can meet the daily nutritional needs of a human body, and help increase of satiety, inhibit energy conversion, plays the effects of reducing weight, alleviating body fat and lowering blood pressure in long-term consumption, has a positive effect on improvement of physical health status and good storage ability, and improves stability in shelf life.

The invention, which is applicable to the technical field of medical detection, provides an ischemia modified albumin detection kit, which comprises an R1 reagent and an R2 reagent. The R1 reagent comprises the following components: 0.02 to 0.1 mol/L of phosphate buffers, 5 to 10mmol/L of a cobalt chloride solution, 0.02 to 0.08g/L of preservatives, and 0.5 to 1.5g/L of stabilizers. The R2 reagentincludes the following components: 0.05 to 0.15 mol/L of phosphate buffers, 6 to 15 mmol/L of dithiothreitol, 0.3 to 0.7 g/L of surfactants, and 0.02 to 0.08 g/L of preservatives. The kit can be applied to detection of the content of ischemia-modified albumin in the human serum; the detection result has high repeatability and high precision; and the highest detection range can reach 200.4 U/mL. The kit has the great linical application value.