The invention discloses a rubber seal ring which is prepared from, by weight, 50-80 parts of butadiene-acrylonitrile rubber, 20-30 parts of butadiene styrene rubber, 10-12 parts of epoxy butyl oleate, 3-5 parts of n-butyl methacrylate, 5-8 parts of n-butyl methacrylate, 3-4 parts of zinc stearate, 2-3 parts of flint clay powder, 5-8 parts of talcum powder, 3-5 parts of bamboo charcoal fibers, 2-3 parts of hollow microbeads, 10-12 parts of chlorinated paraffin, 3-4 parts of aluminium hydroxide, 5-8 parts of paraffinic oil, 1-3 parts of accelerant CBS, 0.5-0.8 part of a vulcanizing agent, 1-2 parts of an anti-aging agent RD and 1-2 parts of a titanate coupling agent TMC-TTS. The rubber seal ring has excellent wear resistance and high temperature resistance and meanwhile has acid and alkaline corrosion resistance, stripping is easy to conduct, after curing is conducted, the rubber seal ring can be cleaned, disassembling, assembling and repairing are not affected, compressibility and rebound resilience are good, and the rubber seal ring is not softened, decomposed or subjected to brittle rupture at a high temperature, can work for a long time in an acid medium, an alkali medium and the like and is durable in use.