The invention relates to a medical
biological tissue structure and a preparation method and a special device of the medical
biological tissue structure, and belongs to the technical field of
biology,
medical treatment and
medical instruments. The medical
biological tissue structure comprises a hollow
pipe, a functional layer and a synthetic
macromolecule protective film, wherein the hollow
pipe is made of
biological materials containing cells or being free of the cells, and the functional layer is attached to the hollow
pipe and contains or does not contain the cells. The medical biological tissue structure, the preparation method and the special device are based on the attachment cross-linking and
solidity principle, under control of a computer, the hollow pipe is firstly extruded out through a special spraying
nozzle, then the
biological materials are sprayed and attached to the hollow pipe to form the functional layer and accumulated layer by layer to form a composite molding body, and finally a synthetic
macromolecule solution is sprayed to the outer surface of the composite molding body to form the protective film. According to the set molding steps, a three-dimensional structure body which contains synthetic
macromolecule materials, the cells and the natural
biological materials is finally manufactured, has the space complex shape and is of the gap structure is finally manufactured. The medical biological tissue structure can be molded at the normal temperature, the process is simple, the
cell survival rate is high, distribution is even and controllable, and the good
mechanical property and the good
biological property are achieved.