The invention discloses a water-saving and energy-saving ammonia desulphurization ultra-clean discharge system and process capable of preventing ammonia from escaping from aerosol. The system comprises a slurry disturbance system, a cooling concentration crystallization system, a sulfur oxide absorption system, an ammonia capture system, a washing purification system and a crystal particle enlarging system, circulating spray liquid of the desulfurizing tower from bottom to top adopts solutions with different components, and the concentration gradient is decreased progressively so that the desulfurizing efficiency is effectively improved, escape of aerosol and ammonia is avoided, and the phenomena of trailing and falling of ammonia-process desulfurized flue gas are eliminated. Different technologies such as multi-stage cyclone coupling, packing, a demister, an efficient cyclone water film dust collector and a wire mesh demister are combined, optimization of the distribution condition offlue gas in the tower is achieved, the retention reaction time of the flue gas is prolonged, further coagulation of fine particles and trapping of slurry droplets are promoted, the flue gas is washedthrough low-temperature washing liquid of the external cooling tower, cooperative removal of the fine particles is achieved, and ultra-clean emission is achieved.